T33701 |
NM-3
|
181427-78-1
|
98%
|
|
NM-3 is an orally available anti-angiogenic inhibitor with anti-tumour activity.NM-3 is used as a radiation modulator in vitro and in vivo.NM-3 inhibits vascular...
|
T41163 |
ZNL 02-096
|
2414418-49-6
|
98%
|
|
ZNL 02-096 is a rapid and selective degrader of Wee1 (IC50=3.58 nM).ZNL 02-096 selectively degrades Wee1 at submolar concentrations without damaging PLK1, a seco...
|
T11717 |
JHU395
|
2079938-92-2
|
98%
|
|
JHU395 is an orally-bioavailable prodrug of a lipophilic glutamine antagonist (GA), 6-diazo-5-oxo-L-norleucine (DON). It demonstrates delivery of DON to malignan...
|
T60564 |
PI3K/Akt/mTOR-IN-2
|
2757804-89-8
|
98%
|
|
PI3K/Akt/mTOR-IN-2 is a potent PI3K/AKT/mTOR inhibitor.PI3K/Akt/mTOR-IN-2 has anticancer effects and is selective for MDA-MB-231 cells with an IC50 of 2.29 μM.PI...
|
T31020 |
CP 461
|
227619-96-7
|
98%
|
|
CP 461, a specific PDE2A inhibitor, is a novel pro-apoptotic compound that inhibits cyclic GMP phosphodiesterase but not cyclooxygenase-1 or -2. CP 461 inhibits ...
|
T26585 |
AK301
|
314022-97-4
|
98%
|
|
AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM). Colon cance...
|
T72068 |
SFI003
|
2361332-90-1
|
98%
|
|
SFI003 is a novel SRSF3 inhibitor that exerts anticancer activity against colorectal cancer by modulating the SRSF3 / DHCR24 / ROS axis and driving apoptosis in ...
|
TN1393 |
(-)-Anonaine
|
1862-41-5
|
98%
|
|
(-)-Anonaine can be extracted from several species of Magnoliaceae and Annelidae and has antimalarial, antibacterial, antifungal, antioxidant, anticancer, antide...
|
T77520 |
AOH1996
|
2089314-64-5
|
98%
|
|
AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC...
|
T28866 |
Stemazole
|
317337-07-8
|
98%
|
|
Stemazole is a novel small molecule human stem/progenitor cell proliferation activator that promotes the survival of human embryonic stem cells and maintains ste...
|
T28498L |
Rac-CCT-250863 HCl
|
T28498L
|
98%
|
|
rac-CCT-250863 HCl is a selective and reversible inhibitor of NEK 2. rac-CCT-250863 HCl induces cell cycle arrest and has good anti-proliferative activity agains...
|
T39030 |
HBDDE
|
154675-18-0
|
98%
|
|
HBDDE is a selective model inhibitor of the isoenzymes PKCα and PKCγ with IC 50 s of 43 μM and 50 μM, respectively.HBDDE has a higher affinity for PKCα/PKCγ than...
|
T67699L |
(R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride
|
T67699L
|
98%
|
|
(R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride possesses anti-apoptotic, ...
|
T27417L |
Glutathione arsenoxide hydrochloride
|
T27417L
|
98%
|
|
Glutathione arsenoxide hydrochloride is a potentially active anti-cancer molecule and inhibitor of tumour metabolism. glutathione arsenoxide hydrochloride target...
|
T6810 |
CPI-360
|
1802175-06-9
|
98%
|
|
CPI-360 is a small molecule EZH2 inhibitor (IC50: 0.002 μM, EC50: 0.080 μM) that shows antitumor activity in an EZH200-dependent tumor xenograft model.
|
T35528 |
TD52
|
1798328-24-1
|
98%
|
|
TD52 is an orally active inhibitor of cancerous inhibitor of PP2A (CIP2A). TD52 is an Erlotinib derivative and indirectly reduced CIP2A by disturbing Elk1 bindin...
|
T8199 |
(±)-α-Bisabolol
|
515-69-5
|
98%
|
|
(±)-α-Bisabolol isa sesquiterpenol extracted from essential oils of chamomile, candida and other plants. It isa natural antiseptic with soothing, antiirritating,...
|
T14378 |
AZD5582
|
1258392-53-8
|
98%
|
|
AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.
|
TQ0215 |
Salinomycin sodium salt
|
55721-31-8
|
98%
|
|
Salinomycin sodium salt, an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.
|
TN3910 |
Ecdysone
|
3604-87-3
|
98%
|
|
Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death. A nctional Bombyx Ecdysone receptor binds to EcRE-D a...
|