T35528 |
TD52
|
1798328-24-1
|
99.5%
|
|
TD52 is an orally active inhibitor of cancerous inhibitor of PP2A (CIP2A). TD52 is an Erlotinib derivative and indirectly reduced CIP2A by disturbing Elk1 bindin...
|
T8199 |
(±)-α-Bisabolol
|
515-69-5
|
99.44%
|
|
(±)-α-Bisabolol isa sesquiterpenol extracted from essential oils of chamomile, candida and other plants. It isa natural antiseptic with soothing, antiirritating,...
|
T14378 |
AZD5582
|
1258392-53-8
|
98.83%
|
|
AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.
|
TQ0215 |
Salinomycin sodium salt
|
55721-31-8
|
98%
|
|
Salinomycin sodium salt, an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.
|
TN3910 |
Ecdysone
|
3604-87-3
|
100%
|
|
Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death. A nctional Bombyx Ecdysone receptor binds to EcRE-D a...
|
T1947 |
BS-181
|
1092443-52-1
|
|
|
BS-181 is a highly selective CDK7 inhibitor (IC50: 21 nM); >40-fold selective for CDK7 than CDK1/2/4/5/6/9.
|
T3340 |
SCR7
|
1533426-72-0
|
|
|
SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).
|
T3081L |
EPZ004777 hydrochloride
|
1380316-03-9
|
|
|
EPZ004777 hydrochloride is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
|
T4114 |
Diffractaic Acid
|
436-32-8
|
|
|
Diffractaic Acid can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.
|
T4134L |
OTS514
|
1338540-63-8
|
|
|
OTS514 is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell l...
|
T6724 |
Voreloxin
|
175414-77-4
|
98%
|
|
Voreloxin is a potent Topoisomerase II inhibitor with broad-spectrum anti-tumor activity. Phase 2.
|
TN1694 |
Gliotoxin
|
67-99-2
|
98%
|
|
Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signalin...
|
T77713 |
BTM-3566
|
2228857-70-1
|
98%
|
|
BTM-3566 activates the ISR through the mitochondrial protease OMA1.BTM-3566 induces apoptosis in cancer cells. BTM-3566 overactivates the mitochondrial ISR to st...
|
T3S0541 |
Curzerene
|
17910-09-7
|
98%
|
|
Curzerene, a sesquiterpene compound derived from the rhizome of Curculigo orchioides Gaertn, possesses potent anti-cancer properties. It is known to induce apopt...
|
TN5280 |
(-)-Zeylenol
|
78804-17-8
|
98%
|
|
(-)-Zeylenol is a natural product derived from the stems of the Uvaria grandiflora, showing anti-inflammatory, antifeedant and antitumor biological activity, act...
|
TN2091 |
Polygalacin D
|
66663-91-0
|
98%
|
|
Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS...
|
T64533 |
Ceramide (Egg, Chicken)
|
477243-06-4
|
98%
|
|
Ceramide (Egg, Chicken) plays a major role in the anabolic and catabolic pathways of sphingolipid. Ceramide (Egg, Chicken) stimulates many cell differentiation, ...
|
TN6097 |
Girinimbine
|
23095-44-5
|
98%
|
|
Girinimbine is a carbazole alkaloid isolated from the plants M. koenigii, M. koenigii and Murraya koenigii.Girinimbine has a wide range of biological effects, in...
|
T19886 |
Cirsilineol
|
41365-32-6
|
98%
|
|
Cirsilineol is isolated from the herb of Artemisia vestita Wall and shows immunosuppressive, anti-proliferative, and anti-tumor properties. Cirsilineol selective...
|
TN3616 |
Cedrelone
|
1254-85-9
|
98%
|
|
Cedrelone is a citrulline analog and a phenazine biosynthesis-like domain protein (PBLD) activator.Cedrelone induces apoptosis in cancer cells.Cedrelone is a ver...
|