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Tafasitamab
(Synonyms: XmAb5574, Tafasitamab-cxix, MOR00208) Copy Product Info
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Synonyms: XmAb5574, Tafasitamab-cxix, MOR00208
Catalog No. T77135 Copy Product Info
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Tafasitamab (XmAb5574) is an FC-modified humanized monoclonal antibody targeting the human B-cell surface antigen CD19 for the study of diffuse large B-cell lymphoma.
Cas No. 1422527-84-1
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $239 | In Stock | In Stock | |
| 5 mg | $787 | In Stock | In Stock | |
| 10 mg | $1,230 | - | In Stock | |
| 25 mg | $2,380 | - | In Stock | |
| 50 mg | $3,230 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.5% (SDS-PAGE); 99.3% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
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| Description | Tafasitamab (XmAb5574) is an FC-modified humanized monoclonal antibody targeting the human B-cell surface antigen CD19 for the study of diffuse large B-cell lymphoma. |
| In vitro | In an E/T ratio-dependent manner, tafasitamab (XmAb5574) induced cytotoxicity to Mino and Jeko (MCL) cell lines. It also increased antibody-dependent cellular phagocytosis (ADCP) and antiproliferative activity. Additionally, tafasitamab (XmAb5574) can enhance the anti-proliferative activity induced by caspase-mediated apoptosis[1][2]. |
| In vivo | In a xenograft tumor model of disseminated BL mice, tafasitamab (2.5 μg/kg, once on day 1) inhibited lymphoma growth[1]. |
| Endotoxin | <1.0 EU/mg |
| Synonyms | XmAb5574, Tafasitamab-cxix, MOR00208 |
| Reactivity | Human |
| Verified Activity | Immobilized Human CD19 Protein (His) (TMPY-01949) at 8 μg/mL (100 μL/well) can bind Tafasitamab. The EC50 is 9.53 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD19 |
| Molecular Weight | 147.41 kDa |
| Cas No. | 1422527-84-1 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Tafasitamab chemical structure | Tafasitamab in vivo | Tafasitamab in vitro | Tafasitamab molecular weight
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