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Benufutamab (Synonyms: Hx-DR5-05, Hx-DR5-01, GEN1029, GEN 1029)
Catalog No. T76925 Copy Product Info
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Benufutamab (GEN1029) is an agonistic antibody targeting death receptor 5 (DR5) with anti-tumor activity, used in the study of solid tumors.
Benufutamab
Copy Product Info🥰Excellent
Catalog No. T76925
Synonyms Hx-DR5-05, Hx-DR5-01, GEN1029, GEN 1029
Benufutamab (GEN1029) is an agonistic antibody targeting death receptor 5 (DR5) with anti-tumor activity, used in the study of solid tumors.
Benufutamab
Cas No. 2109730-69-8
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $328 | In Stock | In Stock | |
| 5 mg | $993 | In Stock | In Stock | |
| 10 mg | $1,590 | - | In Stock | |
| 25 mg | $2,360 | - | In Stock | |
| 50 mg | $3,180 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.62% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Benufutamab (GEN1029) is an agonistic antibody targeting death receptor 5 (DR5) with anti-tumor activity, used in the study of solid tumors. |
| In vitro | Benufutamab (20 μg/mL, 24h) induced cytotoxicity in primary multiple myeloma (MM) cells with a median cell killing rate of 36%. [1] |
| In vivo | The antitumor activity of Benufutamab (0.5 mg/ kg-10 mg/kg, intravenously administered once a week) was confirmed in models of colorectal, pancreatic, gastric, NSCLC, and melanoma cell lines, showing significant antitumor activity. |
| Synonyms | Hx-DR5-05, Hx-DR5-01, GEN1029, GEN 1029 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFRSF10B/TRAILR2/CD262 |
| Molecular Weight | 145.1 kDa |
| Cas No. | 2109730-69-8 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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