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Benufutamab
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Catalog No. T76925Cas No. 2109730-69-8
Alias Hx-DR5-05, Hx-DR5-01, GEN1029, GEN 1029
Benufutamab (GEN1029) is an agonistic antibody targeting death receptor 5 (DR5) with anti-tumor activity, used in the study of solid tumors.
Benufutamab
Benufutamab
😃Good
Catalog No. T76925Alias Hx-DR5-05, Hx-DR5-01, GEN1029, GEN 1029Cas No. 2109730-69-8
Benufutamab (GEN1029) is an agonistic antibody targeting death receptor 5 (DR5) with anti-tumor activity, used in the study of solid tumors.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $328 | In Stock | In Stock | |
| 5 mg | $993 | In Stock | In Stock | |
| 10 mg | $1,590 | - | In Stock | |
| 25 mg | $2,360 | - | In Stock | |
| 50 mg | $3,180 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.62% (SEC-HPLC)
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| Description | Benufutamab (GEN1029) is an agonistic antibody targeting death receptor 5 (DR5) with anti-tumor activity, used in the study of solid tumors. |
| In vitro | Benufutamab (20 μg/mL, 24h) induced cytotoxicity in primary multiple myeloma (MM) cells with a median cell killing rate of 36%. [1] |
| In vivo | The antitumor activity of Benufutamab (0.5 mg/ kg-10 mg/kg, intravenously administered once a week) was confirmed in models of colorectal, pancreatic, gastric, NSCLC, and melanoma cell lines, showing significant antitumor activity. |
| Synonyms | Hx-DR5-05, Hx-DR5-01, GEN1029, GEN 1029 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFRSF10B/TRAILR2/CD262 |
| Molecular Weight | 145.1 kDa |
| Cas No. | 2109730-69-8 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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