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Flurochloridone
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Catalog No. T20543Cas No. 61213-25-0
Alias R-40244, R40244, R 40244, EPA Pesticide Chemical Code 128401
Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.
Flurochloridone
😃Good
Purity: 99.86%
Catalog No. T20543Alias R-40244, R40244, R 40244, EPA Pesticide Chemical Code 128401Cas No. 61213-25-0
Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $35 | In Stock | In Stock | |
| 25 mg | $64 | In Stock | In Stock | |
| 50 mg | $98 | In Stock | In Stock | |
| 100 mg | $158 | In Stock | In Stock | |
| 200 mg | $237 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.86%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses. |
| In vitro | Flurochloridone induced apoptosis in TM4 cells, accompanied by reactive oxygen species (ROS) accumulation, intracellular calcium increase, opening of mitochondrial permeability transition pore, depolarization of the mitochondrial membrane potential (MMP) and decrease of adenosine triphosphate (ATP) level. Pretreatment with ROS scavenger N-acetyl-L-cysteine (NAC), could significantly alleviate Flurochloridone-induced TM4 cells apoptosis and MMP depolarization[2]. |
| Synonyms | R-40244, R40244, R 40244, EPA Pesticide Chemical Code 128401 |
| Molecular Weight | 312.12 |
| Formula | C12H10Cl2F3NO |
| Cas No. | 61213-25-0 |
| Smiles | FC(F)(F)c1cccc(c1)N1CC(CCl)C(Cl)C1=O |
| Relative Density. | 1.3924 g/cm3 (Estimated) |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (192.23 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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