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Flurochloridone

Name: Flurochloridone
Brand: TargetMol
SKU: T20543
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20543Cas No. 61213-25-0

Alias R-40244, R40244, R 40244, EPA Pesticide Chemical Code 128401

Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.

Flurochloridone

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Purity: 99.86%

Catalog No. T20543Alias R-40244, R40244, R 40244, EPA Pesticide Chemical Code 128401Cas No. 61213-25-0

Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$35	In Stock	In Stock
25 mg	$64	In Stock	In Stock
50 mg	$98	In Stock	In Stock
100 mg	$158	In Stock	In Stock
200 mg	$237	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.86%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.
In vitro	Flurochloridone induced apoptosis in TM4 cells, accompanied by reactive oxygen species (ROS) accumulation, intracellular calcium increase, opening of mitochondrial permeability transition pore, depolarization of the mitochondrial membrane potential (MMP) and decrease of adenosine triphosphate (ATP) level. Pretreatment with ROS scavenger N-acetyl-L-cysteine (NAC), could significantly alleviate Flurochloridone-induced TM4 cells apoptosis and MMP depolarization[2].
Synonyms	R-40244, R40244, R 40244, EPA Pesticide Chemical Code 128401

Chemical Properties

Molecular Weight	312.12
Formula	C₁₂H₁₀Cl₂F₃NO
Cas No.	61213-25-0
Smiles	FC(F)(F)c1cccc(c1)N1CC(CCl)C(Cl)C1=O
Relative Density.	1.3924 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (192.23 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2039 mL	16.0195 mL	32.0390 mL	160.1948 mL
5 mM	0.6408 mL	3.2039 mL	6.4078 mL	32.0390 mL
10 mM	0.3204 mL	1.6019 mL	3.2039 mL	16.0195 mL
20 mM	0.1602 mL	0.8010 mL	1.6019 mL	8.0097 mL
50 mM	0.0641 mL	0.3204 mL	0.6408 mL	3.2039 mL
100 mM	0.0320 mL	0.1602 mL	0.3204 mL	1.6019 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc