nsf

Glycosyltransferase-IN-1 is a glycosyltransferase inhibitor with bacteriostatic activity, inhibiting MSSA, MRSA, Bacillus subtilis, and Enterobacteriaceae.

Histone acetyltransferase p300 Inhibitor 4c is a 2-aminothiazole derivative. Histone acetyltransferase p300 Inhibitor 4c inhibited hCA I, hCA II, AChE and BChE with Ki values of 0.008 ± 0.001, 0.124 ± 0.017, 0.129 ± 0.030 and 0.083 ± 0.041 µM. 0.017, 0.129 ± 0.030 and 0.083 ± 0.041 μM.

TAT-NSF700 Fusion Peptide, a potent inhibitor of N-ethyl-maleimide-sensitive factor (NSF), possesses the ability to penetrate cell membranes and directly interact with intracellular organelles [1].

TAT-NSF700scr comprises the complete TAT domain and a glycine linker, succeeded by the NSF amino acids arranged randomly. It serves as a control peptide, ineffective in inhibiting SNARE-mediated exocytosis [1] [2].

TAT-NSF700 Fusion Peptide acetate is a membrane-permeable inhibitor of N-ethyl-maleimide-sensitive factor (NSF), a fusion peptide with potential anti-inflammatory activity.TAT-NSF700 Fusion Peptide acetate interacts with intracellular organelles and can be used to investigate Myocardial ischemia and reperfusion injury.

TAT-NSF222 Fusion Peptide is a bifunctional polypeptide comprising a TAT domain for cellular uptake via macropinocytosis and an NSF domain that inhibits N-ethylmaleimide-sensitive factor (NSF), serving as an exocytosis inhibitor [1].

Transferrin is the principal iron-binding protein in animal serum and is analogous in its iron-binding site and properties to lactoferrin1. Human transferrin is a single-chain glycoprotein of molecular weight near 80,000. The molecule is arranged in two l

Lactoferricin H, Lactotransferrin (37-61), human, is a bioactive peptide with antimicrobial properties, derived from amino acid residues 37-61 of human lactotransferrin.

Alpha-1,3-Galactosyltransferase (GTB) (alpha 1,3GT) is responsible for catalyzing the synthesis of the α-galactose (α-Gal) epitope, known as a xenoantigen. This enzyme facilitates the transfer of galactose from UDP-Gal to either type 1 or type 2 αFuc1→2βGal-R (H)-terminating acceptors [1].

Purinephosphoribosyltransferase-IN-1 (Compound (S,R)-48) is a potent inhibitor of Plasmodium falciparum (Pf), Plasmodium vivax (Pv), and Trypanosoma brucei (Tbr) 6-oxopurine phosphate ribosyltransferase (PRT), with Ki values of 50 nM, 20 nM, and 2 nM, respectively.

Catechol O-methyltransferase (COMT) is a key enzyme in the regulation of melatonin synthesis, which is involved in the regulation of plant growth and development, and can be inhibited by structurally specific heparin oligosaccharides.

Diacylglycerol Acyltransferase Inhibitor-1, a diacylglycerol acyltransferase (DGAT1) inhibitor, effectively suppresses the activity of DGAT1.

Alanine aminotransferase (ALT), a pyridoxal-dependent enzyme, catalyzes the reversible interconversion of L-alanine and 2-oxoglutarate into pyruvate and L-glutamate [1].

N-acetylglucosamine-1-P uridyltransferase (AGX1) (GlcNAc1pUT) is a bifunctional enzyme that catalyzes the synthesis of UDP-GlcNAc by coupling GlcNAc-1-P and UTP through an uridyltransfer reaction, exhibiting both acetyltransferase and uridyltransferase activities, and is exclusive to prokaryotes [1].

Alpha-1,4-Galactosyltransferase (LgtC) (A4GALT), a glycosphingolipid-specific glycosyltransferase, catalyzes the transfer of a galactose molecule to the alpha-1,4 position on lactosylceramide, resulting in the formation of globotriaosylceramide. This enzyme plays a crucial role in the synthesis of P1 blood group antigens [1] [2].

Transfectam, a cationic lipid, forms complexes with DNA, facilitating efficient gene transfer into a range of eukaryotic cells [1].

Gamma-Glutamyl Transferase-IN-2 (compound 4dq), a β-carboline 1-hydrazide inhibitor, exhibits antifungal and antibacterial properties by targeting glutamyltransferase, inducing reactive oxygen species accumulation, compromising cell membranes, and disrupting histone acetylation processes [1].

Phosphate acetyltransferase, a transferase enzyme utilized in biochemical research, catalyzes the reversible acetylation of CoA from acetyl-P, yielding acetyl-CoA and inorganic phosphate. This process is integral to acetate assimilation dissimilation reactions [1].

Transferrin fragment acetate is the principal ironbinding protein in animal serum and is analogous in its iron-binding site and properties to lactoferrin1.

Transfluthrin is a volatile pyrethroid insecticide that targets insect voltage-gated sodium channels (VGSC).

Purine phosphoribosyltransferase-IN-2 is a potent inhibitor of Plasmodium falciparum (Pf), Plasmodium vivax (Pv), and Trypanosoma brucei (Tbr) 6-oxopurine phosphoribosyltransferase (PRT) with Ki values of 30, 20, and 2 nM, respectively.

Diacylglycerolacyltransferaseinhibitor-2 (Example 8) acts as an inhibitor for diacylglycerol acyltransferase 2 (DGAT2), exhibiting an IC50 value of 3.7 nM.

Beta-1,4-Galactosyltransferase (LgtB) (B4GALT1(LgtB)), a key enzyme in biochemical research, catalyzes the transfer of UDP-galactose to N-acetylglucosamine, resulting in the synthesis of galactose beta-1,4-N-acetylglucosamine [1].

Alpha-1,3 4-Fucosyltransferase (α1,3 4FucT) (Hp3 4FT) is found in Helicobacter pylori and catalyzes the transfer of fucose from donor GDP-beta-l-fucose to the GlcNAc [1].