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Anti-Transferrin Antibody (3L945)
😃Good
Catalog No. TMAY-01470
Alias transferrin, F3, Cf-3, Cf3
Anti-Transferrin Antibody (3L945) is a Mouse antibody targeting Transferrin. Anti-Transferrin Antibody (3L945) can be used in ELISA(Cap).
Anti-Transferrin Antibody (3L945)
Anti-Transferrin Antibody (3L945)
😃Good
Catalog No. TMAY-01470Alias transferrin, F3, Cf-3, Cf3
Anti-Transferrin Antibody (3L945) is a Mouse antibody targeting Transferrin. Anti-Transferrin Antibody (3L945) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Transferrin Antibody (3L945) is a Mouse antibody targeting Transferrin. Anti-Transferrin Antibody (3L945) can be used in ELISA(Cap). |
| Alias | transferrin, F3, Cf-3, Cf3 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 3L945 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Transferrin / TF (rh Transferrin / TF; TMPY-01279; NP_001054.1; Met1-Pro698). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of Transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte / pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. Transferrins are iron binding transport proteins that bind Fe3+ion in association with the binding of an anion, usually bicarbonate. This transferrin binds only one Fe3+ion per protein molecule. Transports iron ions from the hemolymph into the eggs during the vitellogenic stage. Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. When a transferrin loaded with iron encounters with a transferring receptor on cell surface, transferring binds to it and, as a consequence, is transported into the cell in a visicle by receptor-mediated endocytosis. The PH is reduced by hydrogen iron pumps. The lower pH causes transferrin to release its iron ions. The receptor is then transported through the endocytic cycle back to the cell surface, ready for another round of iron uptake. Each transferrin molecule has the ability to carry two iron ions in the ferric form. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human Transferrin / TF Protein (TMPY-01279) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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