pen

PEN (human) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.

Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide. Activates phospholipase C (PLC)-mediated signaling cascade in mouse hypothalamus.

PEN (rat) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.

PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83.

PEN(mouse) acetate (proSAAS(221-242) Acetate) (1236955-25-1 Free base) is a polypeptide derivative.

PEN-866 is a potential agent for controlling early stage tumor growth for non-small cell lung cancer (NSCLC). PEN-866 is a novel esterase-cleavable conjugate of an HSP90i and a topoisomerase I inhibitor, SN-38

PEN-221 is a Somatostatin receptor 2 (SSTR2)-targeting cytotoxic conjugate with an IC50 of 10 nM. PEN-221 is a conjugate consisting of microtubule-targeting agent DM1 linked to the C-terminal side chain of Tyr3-octreotate.

DM-CHOC-PEN is a DNA alkylation agent that may be used to treat brain cancer.

AS 183 is an inhibitor of cholesterol acyltransferase (ACAT).

PEN (rat) TFA, a predominant hypothalamic neuropeptide originating from the proprotein ProSAAS, serves as an endogenous ligand for GPR83 [1].

N3-Pen-Dde is a click chemistry reagent containing an azido group.

N3-Pen-Dtpp is a click chemistry reagent containing an azide group.

Pen-N3 is a PDZ peptide that inhibits Wnt/b-catenin signaling by recognizing disordered proteins.

G-Pen-GRGDSPCA TFA is an αvβ3 inhibitory RGD peptide. It inhibits neointimal hyperplasia and luminal narrowing following vascular injury and regulates the migration and proliferation of smooth muscle cells. This compound can be utilized in studies related to mechanisms of vascular injury repair.

[R-(Z)]-4-Amino-3-chloro-2-pentenedioic acid inhibits Micrococcus luteus.

Enkephalin, pen(2,5)- is a bioactive chemical.

[DPen2, Pen5] Enkephalin, a selective δ-opioid receptor analog of [Leu5]-Enkephalin, exhibits specificity towards δ-opioid receptors.

[Deamino-Pen1,Val4,D-Arg8]-vasopressin (AVP-A) is an antagonist of arginine-vasopressin (AVP) that effectively reduces plasma aldosterone concentration in rats and is used to study the growth and steroidogenic capacity of the rat adrenal zona glomerulosa [1].

Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, Artamine chelates with heavy metals and increases their urinary excretion.

Pentiapine (CGS 10746) is a novel inhibitor of dopamine release.

Gadopentetic acid (gadolinium complex) (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies.

Penbutolol sulfate ((-)-Terbuclomine) binds to both β2-adrenergic and β1-adrenergic receptors, making it a non-selective β-blocker.

Pipendoxifene hydrochloride is a selective modulator of estrogen receptor.

Propentofylline (Hextol) is a methylxanthine derivative with neuroprotective, antiproliferative, and anti-inflammatory activity and enhanced synaptic adenosine signaling, which may be useful in the study of Alzheimer's disease, vascular dementia, cognitive impairment, dementia, and chronic pain.