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Results for "

antibiotic

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    2745
    TargetMol | Inhibitors_Agonists
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    83
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    1249
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    TargetMol | Inhibitors_Agonists
Cyclosporin A
Cyclosporine A, Cyclosporine, Ciclosporin
T094559865-13-3
Cyclosporin A is a natural product and an active fungal metabolite, classified as a cyclic polypeptide immunosuppressant. It binds to cyclophilin and inhibits the activity of calcineurin (IC₅₀ = 7 nM) as well as CD11a/CD18 adhesion molecules. It is commonly used to induce uremia models.
  • $36
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Hygromycin B
Hygrovetine
T102231282-04-9
Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis in both prokaryotic and eukaryotic cells by interfering with translocation and causing mistranslation by the 70S ribosome. It is commonly used for the selection of cells transfected with the hph or hyg resistance gene.
  • $35
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TargetMol | Inhibitor Hot
Dexamethasone
Prednisolone F, NSC 34521, MK 125, Hexadecadrol
T107650-02-2
Dexamethasone is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory, immunosuppressive, and apoptosis-inducing activities. It inhibits the production of inflammatory miRNA-155 exosomes in macrophages, significantly reduces inflammatory cytokine expression in neutrophils and monocytes, suppresses LPS-induced macrophage inflammation, and induces autophagy. It is commonly used to induce animal models of depression, muscle atrophy, and hypertension, and holds potential in COVID-19 research.
  • $29
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TargetMol | Inhibitor Hot
Streptozotocin
U 9889, STZ, Streptozocin, NSC-85998
T150718883-66-4
Streptozotocin (Streptozocin, NSC-85998) is an antibiotic that enters pancreatic β-cells via the glucose transporter (GLUT2) and induces DNA methylation, leading to β-cell apoptosis. It is toxic to insulin-producing cells and commonly used to establish diabetic animal models. This product is unstable in solution and is recommended to be prepared freshly before use.
  • $30
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TargetMol | Inhibitor Hot
Doxycycline
Vibramycin, Doxytetracycline, Doxycyclinum, Doxiciclina
T1687564-25-0
Doxycycline is an orally active tetracycline antibiotic with broad-spectrum inhibitory effects on matrix metalloproteinases (MMPs), possessing both antibacterial and antitumor activities, and is commonly used in inducible gene expression ON-OFF systems.
  • $30
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TargetMol | Inhibitor Hot
Doxycycline (hyclate)
WC2031, Doxycycline hydrochloride hemiethanolate hemihydrate, Doxycycline hyclate
T1687L24390-14-5
Doxycycline (hyclate) is an orally active tetracycline antibiotic with broad-spectrum inhibitory activity against matrix metalloproteinases (MMPs), possessing both antibacterial and antitumor properties, and is commonly used in inducible gene expression ON-OFF systems.
  • $41
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TargetMol | Inhibitor Hot
Bleomycin Sulfate
NSC125066, Blenoxane
T61169041-93-4
Bleomycin sulfate is a glycopeptide antibiotic with antitumor activity. It is commonly used as a DNA-damaging agent and DNA synthesis inhibitor. It functions by inducing DNA strand breaks without affecting RNA strands. Bleomycin sulfate is widely used in cancer research and for establishing pulmonary fibrosis animal models.
  • $37
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TargetMol | Inhibitor Hot
Vancomycin
T86411404-90-6
Vancomycin is a glycopeptide antibiotic that exerts its antibacterial activity by inhibiting the second stage of cell wall synthesis in susceptible bacteria. It also alters cell membrane permeability and selectively inhibits RNA synthesis. Vancomycin is commonly used to treat severe infections resistant to other antibiotics and is frequently employed in experimental studies to induce kidney injury models.
  • $30
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TargetMol | Inhibitor Hot
Nitrofurazone
Nitrofural, NFZ, Furacilin
T089759-87-0
Nitrofurazone (Nitrofural; Furacilin) is an orally active nitroaromatic broad-spectrum antibiotic with activity against both Gram-positive and Gram-negative bacteria. It is commonly used for establishing breast cancer models.
  • $30
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Tetracycline
Tetracyclinum, Tetracyclin, Deschlorobiomycin
T0912L60-54-8
Tetracycline is an orally active broad-spectrum antibiotic that exhibits inhibitory activity against various Gram-positive and Gram-negative bacteria, as well as Chlamydia, Mycoplasma, and Rickettsia. It is commonly used in anti-infection research and can also be used to induce tumor regression based on BCR-ABL gene silencing.
  • $33
In Stock
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Tacrolimus
Fujimycin, FR900506, FK506
T2144104987-11-3
Tacrolimus (FK506, Fujimycin) is a macrolide immunosuppressant that binds to FKBP12 to form a high-affinity complex (Ki = 0.2 nM), which inhibits calcineurin phosphatase activity, thereby suppressing T lymphocyte signal transduction and the transcription and release of IL-2. It exerts potent immunosuppressive effects and can be used to induce immunosuppression models.
  • $38
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Doxycycline hydrochloride
Vibramycin, Hyclate, Doxylin
T114010592-13-9
Doxycycline hydrochloride (Hyclate) is an orally active tetracycline antibiotic with broad-spectrum matrix metalloproteinase (MMP) inhibitory activity, possessing both antibacterial and anti-cancer cell proliferation effects, and can be used to induce gene expression in ON-OFF systems.
  • $30
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Puromycin aminonucleoside
NSC 3056
T1668458-60-6
Puromycin aminonucleoside (NSC 3056) is an aminonucleoside antibiotic and a purine analog of puromycin. It can reversibly inhibit dipeptidyl peptidase and cytosolic alanine aminopeptidase, increase podocyte permeability by regulating ZO-1 in an oxidative stress-dependent manner, induce apoptosis, and promote the secretion of migrasomes. It is commonly used to induce nephrotic syndrome models in research.
  • $39
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Doxorubicin
Hydroxydaunorubicin, DOX, Adriamycin
T145623214-92-8
Doxorubicin (Adriamycin) is a fluorescent anthracycline antitumor antibiotic that inhibits Topoisomerase I/II, induces apoptosis and autophagy, downregulates the AMPK signaling pathway, and is commonly used in cancer chemotherapy as well as in models of nephritis and heart failure.
  • $39
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Doxorubicin hydrochloride
NSC 123127, Hydroxydaunorubicin hydrochloride, DOX hydrochloride, Adriamycin HCl
T102025316-40-9
Doxorubicin hydrochloride is an anthracycline antibiotic with cytotoxic and antitumor activity. It is an effective inhibitor of human DNA topoisomerase I and II, with IC50 values of 0.8 μM and 2.67 μM, respectively. In addition to inhibiting DNA topoisomerases, it can reduce the phosphorylation of AMPK and its downstream target, acetyl-CoA carboxylase. Doxorubicin hydrochloride also induces apoptosis and autophagy. In animal studies, it is commonly used to induce models of acute renal failure, chronic kidney injury, and heart failure.
  • $34
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TargetMol | Inhibitor Hot
Ethambutol dihydrochloride
Ethambutol 2HCl, Emb dihydrochloride, CL40881
T08101070-11-7
Ethambutol dihydrochloride is an anti-mycobacterial compound that inhibits arabinosyl transferase activity to prevent cell wall formation and can be used to induce hyperuricemia models.
  • $29
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Ethambutol
Myambutol, EMB
T706274-55-5
Ethambutol is an oral anti-tuberculosis drug that inhibits arabinosyl transferase activity, thereby interfering with the synthesis of arabinogalactan and preventing cell wall formation to exert its antibacterial effect; it can also be used for animal models of hyperuricemia and optic neuropathy.
  • $33
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Bleomycin hydrochloride
T6116L67763-87-5
Bleomycin hydrochloride is a glycopeptide antibiotic and a DNA synthesis inhibitor. Bleomycin Sulfate can cause DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has anti-tumor activity.
  • $37
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TargetMol | Inhibitor Hot
Doxycycline calcium
T7543294088-85-4
Doxycycline calcium is an orally active tetracycline antibiotic that also functions as a broad-spectrum matrix metalloproteinase (MMP) inhibitor, exhibiting antibacterial and anti-tumor cell proliferation activities, and is commonly used to induce gene expression in ON-OFF systems.
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