Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as sex, age, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No.	Product name	CAS No.	Purity
T8269	3-Methoxytyramine	554-52-9	98%
T8269	3-Methoxytyramine, an extracellular metabolite of 3-hydroxytyramine/dopamine, is a neuromodulator.
T7711	Uridine triphosphate	63-39-8	98%
T7711	Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.
T7173	[Leu5]-Enkephalin	58822-25-6	98%
T7173	[Leu5]-Enkephalin is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and µ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively)
T14063	7α,25-Dihydroxycholesterol	64907-22-8	98%
T14063	7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholes...
T5614	3-Oxopentanedioic acid	542-05-2	98%
T5614	3-oxoglutaric acid or acetonedicarboxylic acid is a simple carboxylic acid, which may be used as a building block in organic chemistry. It has been found to be a...
T8282	(S)-(−)-Perillyl alcohol	18457-55-1	98%
T8282	(S)-( )-Perillyl alcohol, a monoterpene found in lavender, inhibits the farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptosis....
TP1022	Protirelin Acetate	120876-23-5	98%
TP1022	Protirelin Acetate is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.
T8110	(+)-Longifolene	475-20-7	98%
T8110	(+)-Longifolene is a naturally occurring.
T7475	S-Adenosyl-L-methionine	29908-03-0	98%
T7475	S-Adenosyl-L-methionine is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.
T13802	Oleamide	301-02-0	98%
T13802	Oleamide is an endogenous fatty acid amide and can be used in the synthesis of de novo in the mammalian nervous system.
T9780	3,4, 5-trimethoxyphenylacetic acid	951-82-6	98%
T9780	3,4, 5-trimethoxyphenylacetic acid is a common intermediate in organic synthesis, and its main use is to convert its carboxyl groups to corresponding application...
T65281	Magnesium acetate tetrahydrate	16674-78-5	98%
T65281	Magnesium acetate tetrahydrate is the hydrated form of the anhydrous magnesium acetate salt.Magnesium acetate tetrahydrate is commonly used to synthesize other c...
T20041	2'-Deoxyadenosine	958-09-8	98%
T20041	2'-Deoxyadenosine is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.
TN6833	Octanal	124-13-0	98%
TN6833	octanal is a natural product with antioxidant and antimicrobial activities.
T10148	4-Hydroxynonenal	75899-68-2	98%
T10148	4-Hydroxynonenal (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).
T9857	Vasopressin	11000-17-2	98%
T9857	Vasopressin, a cyclic nine-peptide synthesized by hypothalamic neurons, is one of the hormones involved in peptide prohormone synthesis. Vasopressin is involved ...
T37501	Ethoxyacetic acid	627-03-2	98%
T37501	Ethoxyacetic acid is an endogenous metabolite.
T5848	Biocytin	576-19-2	98%
T5848	Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate o...
T16527	Phytic acid dodecasodium salt hydrate	123408-98-0	98%
T16527	Phytic acid dodecasodium salt hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium salt hydrate inhibits the enzymatic s...
T13481	2-Methoxyestrone	362-08-3	98%
T13481	2-Methoxyestrone is a methoxylated catechol estrogen and metabolite of estrone (pKa: 10.81).