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Tags Metabolism
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ANGPTL

ANGPTL (Angiopoietin-like proteins) is a class of secreted proteins containing ANGPTL1 to ANGPTL8, which have structural similarities to angiopoietins, and play important roles in the regulation of lipid metabolism, angiogenesis, glucose metabolism, inflammation, hematopoiesis, and cancer, among other physiological processes. It plays an important role in the regulation of lipid metabolism, angiogenesis, glucose metabolism, inflammation, hematopoiesis and cancer, and is mainly used in the study of cardiovascular diseases and metabolism.

Evinacumab
REGN1500, REGN 1500
T774921446419-85-7
Evinacumab (REGN1500) is a humanized monoclonal antibody targeting ANGPTL3. It is useful for studying cardiovascular diseases.
ANGPTL
  • 334 €
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Anti-ANGPTL4 Antibody
T9901A-067
Anti-ANGPTL4 Antibody is an IgG1κ humanised antibody inhibitor targeting ANGPTL4.
ANGPTLOthers
  • 110 €
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Solbinsiran
LY3561774
T2173762718150-11-7
Solbinsiran is an siRNA targeting the ANGPTL3 protein in the liver, used in research on dyslipidemia.
ANGPTL
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Solbinsiran sodium
LY3561774 sodium
T2174662707429-60-3
Solbinsiran sodium is an siRNA compound that targets the ANGPTL3 protein in the liver and is used for research in dyslipidemia.
ANGPTL
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Zodasiran sodium
ARO-ANG3 sodium
T2174182232918-74-8
Zodasiran sodium is an siRNA targeting the ANGPTL3 protein in the liver, and it is used in research on hyperlipidemia.
ANGPTL
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Vupanorsen
ISIS 703802, IONIS ANGPT-L3Rx
T876272097587-62-5
Vupanorsen, an N-acetyl galactosamine-conjugated antisense oligonucleotide, inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis and reduces triglycerides and atherogenic lipoproteins.
ANGPTL
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Vupanorsen sodium
ISIS 703802 sodium, IONIS ANGPT-L3Rx sodium
T876262172852-12-7
Vupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide designed to inhibit the synthesis of Angiopoietin-like 3 (ANGPTL3) protein. This compound effectively reduces levels of triglycerides and atherogenic lipoproteins.
ANGPTL
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Anti-ANGPTL8 Antibody
T9901A-1244
Anti-ANGPTL8 Antibody is a specialized monoclonal antibody target the angiopoietin-like 8 protein, restoration of lipoprotein lipase activity by disrupting the inhibitory signaling complex to promote the clearance of triglyceride-rich lipoproteins across various preclinical metabolic experimental models.
ANGPTL
  • 339 €
12 days
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Cartilostatin 1
T82776929555-05-5
Cartilostatin 1, an anti-angiogenic peptide, has potential applications in research focused on angiogenesis inhibition [1].
ANGPTL
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Zodasiran
ARO-ANG3
T2173752232918-66-8
Zodasiran is an siRNA that targets the ANGPTL3 protein in the liver and is utilized in studies of hyperlipidemia.
ANGPTL
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Pegevongitide
TP30982988012-71-9
Pegevongitide acts as an agonist of the angiopoietin-1 receptor.
ANGPTL
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DC371739
DC-371739
T887352135765-21-6
DC371739 is an orally active PCSK9 inhibitor with significant efficacy. This compound effectively reduces PCSK9 and ANGPTL3 mRNA expression, decreases PCSK9 protein expression, and promotes LDLR protein expression, demonstrating potential application value in hyperlipidemia research.
ANGPTL
  • 45 €
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