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Metabolism

Acetyl-CoA Carboxylase

Amino Acids and Derivatives

Angiotensin-converting Enzyme (ACE)

Endogenous Metabolite

Glutathione Peroxidase

(40)

Glyoxalase

(2)

HIF/HIF Prolyl-Hydroxylase

Indoleamine 2,3-Dioxygenase (IDO)

(33)

Isocitrate Dehydrogenase (IDH)

Mitochondrial Metabolism

(94)

N-Acetylglucosaminyltransferase

Procollagen C Proteinase

(1)

Prolyl Endopeptidase (PREP)

Reactive Oxygen Species

Serine/threonin kinase

(47)

Stearoyl-CoA Desaturase (SCD)

Apolipoprotein

Apolipoproteins (Apo) are a class of lipid-bound proteins that primarily transport amphiphilic lipids in blood, cerebrospinal fluid, and lymph, and play a key role in lipid metabolism, uptake, and translocation.Apolipoproteins are an important component of lipoprotein particles (HDL, LDL), and common apolipoproteins include ApoA-I (in HDL, which is associated with cardiovascular), ApoB (in LDL, associated with atherosclerosis), and ApoE (associated with lipid metabolism and neurodegenerative diseases such as Alzheimer's disease).

Filter HomeSignaling PathwaysMetabolismApolipoprotein

EZ-482

T152651016456-76-0

EZ-482 is an apolipoprotein (apoE) ligand that binds to the C-terminal domain of apoE3 and apoE4 through a unique N-terminal allosteric effect, useful in Alzheimer's disease research.

$116

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Anselamimab

T831062414866-63-8

Anselamimab is a humanized IgG1κ monoclonal antibody targeting serum amyloid A1 (SAA1). It removes amyloid deposits by specifically binding to amyloid fibrils and triggering phagocytosis by macrophages and neutrophils.Anselamimab was used as an APP(β-amyloid A4 Protein Precursor ) inhibitor in the clinical phase for the treatment of light chain (AL) amyloidosis.

$247

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APL180 TFA

TP3049

APL180 TFA (L-4F) is an apolipoprotein A-I mimetic peptide that enhances the anti-inflammatory properties of high-density lipoprotein (HDL). APL180 is applicable for cardiovascular disease research.

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APL180

TP2954388566-97-0

APL180 (L-4F) is an apolipoprotein A-I mimetic peptide that enhances the anti-inflammatory activity of high-density lipoprotein (HDL). It is applicable for cardiovascular disease research.

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APOL1-IN-2

T2030302956781-84-1

APOL1-IN-2 (Compound 467) acts as an inhibitor of apolipoprotein L1 (APOL1). It effectively reduces HEK293 cell death induced by APOL1 G2 G1, with EC50 values of 4.74 nM and 14.3 nM, respectively. Additionally, APOL1-IN-2 decreases the mortality of trypanosomes triggered by APOL1 G2 G1 G0, with EC50 values of 2.24, 6.03, and 3.72 nM, respectively.

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10-14 weeks

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APP-018

TP2982452782-06-8

APP-018 (D-4F) is an 18 D-amino acid peptide that mimics apolipoprotein A-I (apoA-I). It enhances the anti-inflammatory properties of high-density lipoprotein (HDL) and is applicable in cardiovascular disease research.

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