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TargetMol | Tags Metabolism
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Transketolase

Transketolase is a thiamine diphosphate (ThDP)-dependent enzyme that plays a crucial role in the pentose phosphate pathway and the reductive pentose phosphate cycle of photosynthesis. There are three isoforms of transketolase: TKT, TKTL1, and TKTL2. Its activity requires the participation of thiamine diphosphate and divalent cations (Mg2+, Ca2+, etc.).

Oxythiamine
T12354136-16-3
Oxythiamine (Hydroxythiamin) is an antivitamin of thiamine and a transketolase (TK) inhibitor. Oxythiamine inhibits cancer cell proliferation and induces cell cycle arrest. Oxythiamine has potential anticancer activity, inhibits non-oxidative synthesis of ribose, and induces apoptosis.
  • $29
In Stock
Size
QTY
Transketolase-IN-4
T72576419547-73-2
Transketolase-IN-4 is a transketolase inhibitor with an IC50 value of 3.9 μM.Transketolase-IN-4 inhibited Mycobacterium tuberculosis DXS with an IC50 value of 114.1 μM. Transketolase-IN-4 inhibited the SW620, LS174T, and MIA PaCa-2 tumor cell proliferation.
  • $30
In Stock
Size
QTY
Transketolase-IN-2
T725572757552-21-7
Transketolase-IN-2 is a potent inhibitor of Transketolase, demonstrating significant inhibitory effects on Digitaria sanguinalis and Amaranthus retroflexus, with over 90% inhibition at 200 mg L and approximately 80% at 100 mg L. This compound is relevant for research in weed control.
  • $1,520
6-8 weeks
Size
QTY
Oxythiamine diphosphate ammonium
T64282
Oxythiamin diphosphate ammonium [OxyThDP, OxiTDP] is a potent inhibitor of transketolase (TK).
  • $1,500
10-14 weeks
Size
QTY
TKL-IN-1
T205736
TKL-IN-1 (compound 7r) serves as an inhibitor of transketolase (Transketolase) and can be utilized as an herbicide. This compound effectively hampers the growth of Digitaria sanguinalis (Ds) and Amaranthus retroflexus (Ar).
  • Inquiry Price
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Transketolase-IN-3
T749812757552-03-5
Transketolase-IN-3, a potent inhibitor of transketolase (TK), exhibits herbicidal activity by effectively suppressing Digitaria sanguinalis (DS) and Amaranthus retroflexus (AR). This compound holds potential for herbicide research applications [1].
  • $1,520
4-6 weeks
Size
QTY
N3PT
T1215813860-66-7
N3PT is a potent and selective inhibitor of transketolase(TK) with IC50 of 22 nM for Apo-TK)
    Inquiry
    Benfooxythiamine
    T204625909542-99-0
    Benfooxythiamine is a transketolase (TKT) inhibitor that suppresses SARS-CoV-2 replication and enhances the activity of the glycolysis inhibitor 2DG. It exhibits antiviral properties.
    • Inquiry Price
    10-14 weeks
    Size
    QTY
    α-Glycerophosphate Dehydrogenase-Triosephosphate
    TRP-00343
    α-Glycerophosphate Dehydrogenase-Triosephosphate (GDH-TIM) is an enzyme mixture composed of glycerophosphate dehydrogenase (GDH) and triosephosphate isomerase (TIM). This compound is employed to measure transketolase (TK) activity in erythrocyte hemolysates, which helps in assessing vitamin B deficiency.
      Inquiry
      Transketolase-IN-5
      T209242
      Transketolase-IN-5 (compound 6ba) is an inhibitor of transketolase. It exhibits herbicidal activity against Amaranthus retroflexus, Setaria viridis, and Digitaria sanguinalis.
        Inquiry
        Transketolase-IN-6
        T209243
        Transketolase-IN-6 (Compound 6bj) serves as a lead compound for herbicides. It achieves approximately 80% root inhibition in redroot pigweed (Amaranthus retroflexus) and green foxtail (Setaria viridis). Moreover, Transketolase-IN-6 is an effective inhibitor of transketolase (TK).
          Inquiry
          Oxythiamine diphosphate
          T12354L10497-04-8
          Oxythiamine diphosphate is a competitivethiamine pyrophosphate inhibitor(Ki of 30 nM).
          • $1,520
          6-8 weeks
          Size
          QTY