complex

MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor (IC50=100 nM) that is cell-permeable and reversible. MG-132 acts as an autophagy activator and also induces apoptosis.

4'-Methylacetophenone can be used as a fragrance material. It is wildly occurred in volatile compounds in food and in some natural complex substances.

Sulbactam sodium (CP-45899-2) (Unasyn) is an irreversible β-lactamase inhibitor.

MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons. MPP+ induces autophagic cell death in SH-SY5Y cells.

(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during necrosis. Prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Binds and inhibits gasdermin D. Inhibits pyroptosis.

Sulbactam (CP45899) is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.

Enniatin complex, a mixture of cyclohexadepsipeptides predominantly derived from various Fusarium species of fungi, exhibits inhibitory effects on enzymes such as acyl-CoA: cholesterol acyl transferase. Furthermore, it has demonstrated the ability to induce apoptosis in multiple cancer cell lines. In addition to these activities, the Enniatin complex possesses ionophoric, antibiotic, and in vitro hypolipidemic properties.

Filipin complex is a 28-membered cyclopentene macrolide antifungal antibiotic produced by a mixture of S. filipinensis, S. avermitilis, and S. miharaensis that inhibits the entry of PRRSV viruses into cells.

Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).

Tyrocidine complex is a mixture of cyclic decapeptides originally isolated from B. brevis. It is active against Gram-positive and Gram-negative bacteria. It forms a complex with single- and double-stranded DNA to inhibit RNA synthesis.

Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.

Bacitracin complex is a bacitracin antibiotic complex composed of cyclic dipeptides that has been found inBacillus.1It is metal-dependent and is complexed to a divalent metal cation, such as Cu2+, Ni2+, Co2+, Zn2+, or Mn2+, for its activity.1,2Bacitracin complex is a mixture of bacitracin polypeptides in complex with copper. 1.Piacham, T., Isarankura-Na-Ayudhya, C., Nantasenamat, C., et al.Metalloantibiotic Mn(II)-bacitracin complex mimicking manganese superoxide dismutaseBiochem. Biophys. Res. Commun.341(4)925-930(2006) 2.Rodríguez-Uribe, N.A., Pérez-González, R., Domínguez-Mendoza, B.E., et al.Metallobacitracins: Affinity and structural study in aqueous solutionInorg. Chem. Commun.10461-70(2019)

Parvodicin complex is a mixture of closely related lipophilic glycopeptides originally isolated from A. parvosata. The parvodicin complex has activity against Gram-positive bacteria (MICs = 0.8-12.5 μg/ml) including methicillin-resistant strains of S. aureus (MRSA), S. hemolyticus, and E. faecalis (MICs = 0.1-25 μg/ml). Glycopeptide antibiotics act by preventing cell wall synthesis by binding and sequestering a cell wall precursor with a D-alanine-containing peptide.

Complex III-IN-2 (Compd 4d-2) is a complex III inhibitor with antifungal activity, exhibiting EC50 values of 29.31 mg L against R. solani and 29.98 mg L against Sclerotinia sclerotiorum [1].

Complex III-IN-1 (Compd 4c-2) is an inhibitor of complex III with antifungal activity, exhibiting an EC50 value of 18.53 mg L against Sclerotinia sclerotiorum [1].

α,α,β,β-d4-Serotonin-Creatinine Sulfate Complex H2O is a deuterated compound of α,α,β,β-Serotonin-Creatinine Sulfate Complex H2O.

Sulfur trioxide-Triethylamine complex is a Lewis acid-base adduct commonly used as a sulfonating agent or Lewis acid catalyst, widely used in biochemical experiments and drug synthesis research.

Nuclear pore complex protein Nup98 (315-360) is the 315-360 fragment part of the nuclear pore complex (NPC) protein.

Quinupristin-Dalfopristin Complex is a mixture of two streptogramin antibiotics. Quinupristin-dalfopristin complex is a mixture of two streptogramin antibiotics, dalfopristin, and quinupristin. Streptogramin antibiotics are divided into types A and B, whi

Deferasirox iron complex is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

o-Cresolphthalein Complexone is a metal complexing indicator and an acid-base indicator.

Thymolphthalein complexone is a reagent used in biochemical reactions.

Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces apoptosis.

RMC-6236 is an orally effective and novel triple complex RAS (ON) MULTI inhibitor, which is a potent non covalent inhibitor of multiple RAS variants in GTP binding state. RMC-6236 has anti-tumor activity and can be used in research related to RAS driven tumors. With rich experience in compound synthesis, we can provide fast customized synthesis services for this product according to your research needs.