cat — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15198	Edasalonexent	CAT-1004	NF-κB
	Edasalonexent is an orally bioavailable inhibitor of NF-κB.		NF-κB
T76704	Tralokinumab	CAT-354,LP 0162	IL Receptor
	Tralokinumab is a fully human IgG4 monoclonal antibody with a high affinity for IL-13 alone. Tralokinumab's potential anti-inflammatory activity prevents IL-13 receptor interaction and subsequent downstream signaling and...		IL Receptor
T1052	Proglumide		cholecystokinin
	Proglumide (Binoside) is a cholecystokinin antagonist, which blocks both the CCKA and CCKB subtypes. Proglumide is a drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is...		cholecystokinin
TQ0038	Brensocatib	AZD7986,INS 1007	Proteasome
	Brensocatib (AZD7986) is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively).		Proteasome
T3023	Catharanthine sulfate		AChR
	Catharanthine inhibits nicotinic receptor-mediated diaphragm contractions.		AChR
T77747	Adecatumumab	MT 201	Others
	Adecatumumab (MT201) is a whole-person IgG1 monoclonal antibody to human EpCAM. Adecatumumab has potential anticancer activity and can be used to study breast cancer.		Others
T10503	ACAT-IN-1 cis isomer		Acyltransferase
	ACAT-IN-1 cis isomer is a potent ACAT inhibitor (IC50: 100 nM) for the study of immune system-related diseases.		Acyltransferase
TP1730L	β-catenin peptide acetate(265669-37-2 free base)		Others
	β-catenin peptide(βCATp) acetate is a naturally occurring self-peptide presented by Kb that very efficiently mediates positive selection of the OT-I thymocytes.		Others
T2782L	Catharanthine Tartrate(2468-21-5(free base))		Calcium Channel
	Catharanthine Tartrate is a natural product isolated from Madagascar periwinkle, Catharanthine Tartrate inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activity		Calcium Channel
TN7047	6-O-Methylcatalpol		Others
	6-O-Methylcatalpol is a natural product that is isolated from the roots of S. ningpoensis.		Others
T23109	3,5-Dinitrocatechol		Transferase
	OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex.		Transferase
T39598	4-Chlorocatechol		Others
	4-Chlorocatechol, a significant degradation product of 4-chloro-2-aminophenol (4C2AP), serves as a substrate for both catechol 1,2-dioxygenases and chlorocatechol dioxygenase [1] [2].		Others
T35868	BCAT-IN-2
	BCAT-IN-2 is a potent, selective and orally active inhibitor of mitochondrial branched-chain aminotransferase (BCATm), with a pIC50 of 7.3. BCAT-IN-2 shows selectivity for BCATm over BCATc (pIC50=6.6). BCAT-IN-2 can be u...
T1239	Indacaterol maleate	QAB149	Adrenergic Receptor
	Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.		Adrenergic Receptor
T9065	4-Isopropylcatechol		Others
	4-Isopropylcatechol is a potent depigmenting agent and is of use in the topical therapy of selected patients with hypermelanosis.		Others
T2320	Indacaterol		Adrenergic Receptor
	Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.		Adrenergic Receptor
T67884	β-catenin modulator IIa-661		Wnt/beta-catenin
	β-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.		Wnt/beta-catenin
T8255	(±)-Catechin	(±)-Catechin hydrate	ROS , COX
	(±)-Catechin ((±)-Catechin hydrate) hydrate is a natural product,has antioxidant activity and is effective in reducing oxidative stress.		ROS , COX
T4779	4-Methylcatechol	p-Methylcatechol,Homocatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene	Others , Endogenous Metabolite
	4-Methylcatechol (3,4-Dihydroxytoluene) is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 2,3-dioxygenase. 4-Methylcatechol (3,4-Dihydroxytoluene) is known to induce t...		Others , Endogenous Metabolite
T2856	(-)-Epicatechin	L-Epicatechin,Epicatechin,(-)-Epicatechol	Ferroptosis , COX , Endogenous Metabolite
	(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.		Ferroptosis , COX , Endogenous Metabolite