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Anti-FZD7 Antibody

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Catalog No. T9901A-1327

Anti-FZD7 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human Frizzled-7 receptor with exceptional binding affinity and selectivity, effectively facilitating the measurable blockade of Wnt ligand interaction across various preclinical experimental models to evaluate the inhibition of canonical beta-catenin signaling and tumor-initiating cell frequency during strictly monitored laboratory observation periods in advanced oncology research environments.

Anti-FZD7 Antibody

Anti-FZD7 Antibody

Copy Product Info
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Catalog No. T9901A-1327
Anti-FZD7 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human Frizzled-7 receptor with exceptional binding affinity and selectivity, effectively facilitating the measurable blockade of Wnt ligand interaction across various preclinical experimental models to evaluate the inhibition of canonical beta-catenin signaling and tumor-initiating cell frequency during strictly monitored laboratory observation periods in advanced oncology research environments.
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Product Introduction

Bioactivity
Description
Anti-FZD7 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human Frizzled-7 receptor with exceptional binding affinity and selectivity, effectively facilitating the measurable blockade of Wnt ligand interaction across various preclinical experimental models to evaluate the inhibition of canonical beta-catenin signaling and tumor-initiating cell frequency during strictly monitored laboratory observation periods in advanced oncology research environments.
In vitro
In CRISPR screen validation and Wnt signaling assays, Anti-FZD7 Antibody blocked Wnt-FZD5 signaling and inhibited the growth of RNF43-mutant pancreatic tumor cells [1].
In vivo
In RNF43-mutant pancreatic cancer xenograft models, systemic administration of Anti-FZD7 Antibody significantly reduced tumor burden and inhibited Wnt signaling in vivo [1].
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetFZD7
Chemical Properties
Antibody Information
IsotypeIgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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