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Cat No. | Product Name | Synonyms | Targets |
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T12316 | Oral antiplatelet agent 1 | Others | |
Oral antiplatelet agent 1 is a potent antiplatelet agent with an IC50 of 2.94 μM in vitro. | |||
T20764 | Dienestrol diacetate | NSC 81279,NSC81279,Cycladiene,Retalon-oral,Oestrasid C,NSC-81279 | |
Dienestrol diacetate, a derivative of the synthetic non-steroid phenolic compound, DIENESTROL, exhibits estrogenic activities. | |||
T19858 | Brodimoprim | DHFR , Antibacterial | |
Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR). Brodimoprim is also a long-acting broad-spectrum antibacterial agent characterized by a good pharmacokinetic profile. | |||
T9680 | Irloxacin | Antibacterial | |
Irloxacin is a new quinolone derivative, and shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. | |||
T10423 | AWZ1066S | Parasite | |
AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay). | |||
T22341 | GSK-114 | Others | |
GSK-114, a selective inhibitor of TNNI3 Interacting Kinase (TNNI3K) with IC50 of 25 nM, shows significant bias for TNNI3K over B-Raf with IC50 of 1000 nM, exceptional broad spectrum kinase selectivity and adequate oral e... | |||
T8850 | Sbp-7455 | Autophagy | |
SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice. | |||
T7436 | Cilofexor | FXR , Autophagy | |
Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist. | |||
T31976 | Glymidine sodium | Others | |
Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secretion. | |||
T5477 | ELQ-300 | Parasite | |
ELQ-300 is bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1) | |||
T9452 | PW0787 | GPR | |
PW0787 is a potent, selective, orally active, and brain-penetrant GPR52 agonist (EC50=135 nM). | |||
T20525 | Chloramphenicol palmitate | Antibacterial , Antibiotic | |
Chloramphenicol palmitate is a broad-spectrum antibiotic with activity against gram-positive and gram-negative bacteria. Chloramphenicol palmitate can be used in studies about acting as a bacterial selection agent in tra... | |||
T11689 | ITI-214 | ITI214 | PDE |
ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = ... | |||
T9706 | BTK inhibitor 17 | BTK | |
BTK inhibitor 17 is a potent irreversible BTK inhibitor (IC50 = 2.1 nM). BTK inhibitor 17 can be used in rheumatoid arthritis studies. | |||
T9121 | AG-636 | Dehydrogenase , DNA/RNA Synthesis | |
AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects. | |||
T41277 | PACMA 31 | Others | |
PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 μM. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability. | |||
T16777 | ROC-325 | Apoptosis , Autophagy | |
ROC-325 is an effective and orally active inhibitor of autophagy with anticancer activity. ROC-325 induces renal cell carcinoma apoptosis and exhibits favorable selectivity. | |||
T2282 | RPI-1 | Others , Phospholipase , c-Met/HGFR , c-RET | |
RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor. | |||
T5315 | TCA1 | TCA-1,TCA 1 | Antibacterial , Antibiotic |
TCA1 (TCA 1) is a small molecule with activity against drug-resistant and persistent tuberculosis. | |||
T16845 | Sarolaner | PF-6450567 | Others , Parasite |
Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata). | |||
T14358 | Avoralstat | BCX4161 | Others |
Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema. | |||
T5513 | RO-3 | P2X Receptor | |
RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor | |||
T11723L | JNJ-39758979 | Histamine Receptor | |
JNJ-39758979 is a selective and high-affinity histamine H4 receptor antagonist (Kis: 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively). JNJ-39758979 functionally antagonizes histamine... | |||
T7388 | GSK805 | ROR | |
GSK805 is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor's putative ligand binding domain without exerting significant effects on DNA bindi... | |||
T9021 | Ro0711401 | Ro-0711401,Ro 0711401 | GluR |
Ro0711401 is an agonist of mGlu1 receptor. | |||
T2086 | ELN-441958 | ELN 441958 | Bradykinin Receptor |
ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM. ELN-441958(ELN 441958) is highly selective for B1 over B2 receptors. | |||
T2007 | RQ-00203078 | TRP/TRPV Channel | |
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist. | |||
T9020 | GSK620 | Epigenetic Reader Domain | |
GSK620 is a pan-BD2 inhibitor, which shows an anti-inflammatory phenotype in human whole blood with excellent broad selectivity, developability, and in vivo oral pharmacokinetics.GSK620 is highly selective for the BET-BD... | |||
T1770 | GNE-9605 | LRRK2 | |
GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM). | |||
T4534 | BMS-309403 | FABP | |
BMS-309403 is an effective, selective and cell-permeable inhibitor of fatty acid binding protein 4 (FABP4) with a Ki of less than 2 nM. | |||
T9470 | HPK1-IN-7 | MAPK | |
HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and GLK (140 nM). | |||
T3072 | XL019 | Apoptosis , FLT , JAK , PDGFR | |
XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1. | |||
T7537 | Norgestimate | Progesterone Receptor | |
Norgestimate is an acetylated progestinused in combination with ethinyl estradiol as an oral contraceptive. | |||
T6400 | AZD3514 | Androgen Receptor | |
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1. | |||
T7879 | TASP0415914 | Akt , PI3K | |
TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T | |||
T10539 | BIBO3304 TFA | Neuropeptide Y Receptor | |
BIBO3304 TFA is an effective, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist (IC50:0.38 and 0.72 nM for the human and the rat Y1 receptor). | |||
T21981 | Phthalazinone pyrazole | Aurora Kinase | |
Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity. | |||
T4584 | BMS-813160 | BMS 813160 | CCR |
BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular. | |||
T1385 | Amlodipine | UK-48340 | Calcium Channel |
Amlodipine (UK-48340) is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. | |||
T4697 | ABBV-744 | ABBV744 | Epigenetic Reader Domain , HIV Protease |
ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS. | |||
T6207 | SC144 | Apoptosis , Interleukin | |
SC144 is an orally active small-molecule gp130 inhibitor. | |||
T6700 | Tenatoprazole | TU-199 | Proton pump |
Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM). | |||
T9499 | Icenticaftor | QBW251 | CFTR |
Icenticaftor (QBW251) is an orally active potentiator of CFTR channel. | |||
T3119 | JNJ-63533054 | JNJ 63533054 | GPR |
JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM. | |||
T14315 | AR-9281 | APAU | Epoxide Hydrolase |
AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes | |||
T22398 | Phenidone | 1-phenyl-3-pyrazolidinone | Lipoxygenase , COX |
Phenidone (1-phenyl-3-pyrazolidinone) is a dual inhibitor of cyclooxygenases and lipoxygenases that ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes[1]. The lipoxyg... | |||
T0231 | Amlodipine Besylate | Amlodipine benzenesulfonate | Calcium Channel |
Amlodipine Besylate(Amlodipine benzenesulfonate) is a long-lasting calcium channel blocker. | |||
T22708 | Darglitazone | CP-86325 | PPAR |
Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid metabolism. | |||
T5414 | Glumetinib | SCC244 | c-Met/HGFR |
Glumetinib (SCC244) (SCC 244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM). | |||
T15430 | GSK2256294A | GSK 2256294 | Others , Epoxide Hydrolase |
GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0912L | Tetracycline | Deschlorobiomycin,Tetracyclinum,Tetracyclin | Others , ribosome , Antibacterial , Antibiotic |
Tetracycline (Tetracyclin) is a naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis. | |||
T2786 | Oxysophocarpine | Prostaglandin Receptor | |
Oxysophocarpine is extracted from Sophra flavescens Ait. | |||
T7938 | Quinidine | Parasite | |
Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria. | |||
T41372 | (22S,23S)-Homobrassinolide | SSHB | Others |
(22S,23S)-Homobrassinolide (SSHB) induces plant growth in various plant bioassay systems. | |||
T0301 | Ethisterone | 17α-Ethynyltestosterone,Pregneninolone | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Ethisterone (17α-Ethynyltestosterone) is a progestogen hormone. | |||
T7964 | Isomalt | Palatinitol,Palatinit | Others , Dehydrogenase |
Isomalt (Palatinitol) is a mixture of 1,6-mannitol glucopyranoside and 1,6-sorbitol glucopyranoside | |||
T0247 | Acarbose | BAY g 5421 | Glucosidase |
Acarbose (BAY g 5421) is an inhibitor of α-Glucosidases with antihyperglycemic activity. | |||
T8117 | Metenolone acetate | Methenolone acetate | Others , Androgen Receptor |
Metenolone acetate (Methenolone acetate) is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure. | |||
T8516 | Levomenol | (-)-α-BISABOLOL | Others |
Levomenol ((-)-α-BISABOLOL) is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities. | |||
T5S2360 | Corydaline | Corydalin,(+)-Corydaline | P450 , Virus Protease , Opioid Receptor , AChE |
1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr... | |||
T12039 | Miglustat | N-Butyldeoxynojirimycin,OGT918,NB-DNJ | Others |
Miglustat (NB-DNJ) is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). | |||
T0687 | Simvastatin | MK-0733,MK 733 | Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy |
Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovasc... | |||
T0700 | Ursodeoxycholic acid | UDCA,Ursodiol | Potassium Channel , Endogenous Metabolite |
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption. | |||
T8125 | Quinidine sulfate dihydrate | Chinidin Sodium,β-quinine Sodium,Pitayine Sodium,Quinidine sulfate | P450 |
Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor | |||
T2S1797 | Santalol | Antioxidant , Antifungal | |
1. Santalol has good antibacterial, anti-oxidation and anti-tumor activities. 2. α-Santalol is a potent antimitotic agent induced by interference with microtubule assembly. 3. α-Santalol shows a significant antifungal ef... | |||
T29078 | Ursodeoxycholic acid sodium | UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium | FXR , Endogenous Metabolite , GPCR19 |
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it... | |||
TN1148 | Isopsoralenoside | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Antibacterial | |
Isopsoralenoside shows estrogen-like, osteoblastic proliferation accelerating, antitumor, and antibacterial effects. | |||
T2942 | Psoralen | Ficusin,Furocoumarin,psoralene | Apoptosis , Influenza Virus , HIV Protease , DNA/RNA Synthesis |
Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division. | |||
TN1343 | 8-Geranyloxypsoralen | Anti-infection , P450 , BACE | |
8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues. 8-Geranyloxypsoralen possesses nematicidal act... | |||
TN1008 | Psoralenoside | CaMK , Calcium Channel , Histamine Receptor | |
Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity. | |||
T3399 | Psoralidin | Others , Estrogen/progestogen Receptor , Reactive Oxygen Species , Lipoxygenase , Gamma-secretase , Akt , COX , Antibacterial | |
Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive properties. | |||
TN3267 | 8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen | Others | |
8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen is a natural product for research related to life sciences. The catalog number is TN3267 and the CAS number is 144398-34-5. | |||
TN3281 | 8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen | Others | |
8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen is a natural product of Psoralea, Fabaceae. The catalog number is TN3281 and the CAS number is 425680-98-4. 8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen can be used as a referen... | |||
TN6298 | 8-[(6,7-Dihydroxy-3,7-dimethyloct-2-en-1-yl)oxy]psoralen | ||
8-[(6,7-Dihydroxy-3,7-dimethyloct-2-en-1-yl)oxy]psoralen is a natural product for research related to life sciences. The catalog number is TN6298 and the CAS number is 889112-17-8. | |||
TN2425 | 5,8-Dihydroxypsoralen | Others | |
5,8-Dihydroxypsoralen is a natural product from Pueraria lobata (Willd.) Ohwi | |||
T40859 | 5-Hydroxy-8-methoxypsoralen | 5-Hydroxyxanthotoxin,5-Hydroxy-8-methoxypsoralen | |
5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite derived from Xanthotoxin, which acts as a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). It is employed as an agent for the t... | |||
T40636 | 8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen | ||
8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin compound present in Heracleum pyrenaicum Lam. | |||
TN6968 | 4",5"-dehydroisopsoralidin | ||
4",5"-dehydroisopsoralidin is a natural product. | |||
TN4630 | Nemoralisin | Others | |
Nemoralisin exhibits weak cytotoxicities (IC50>10 uM) against HepG2, AGS, MCF-7, and A-549 cancer cell lines. | |||
TN3266 | 8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen | Others | |
8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen is a natural product for research related to life sciences. The catalog number is TN3266 and the CAS number is 151121-39-0. | |||
TN4629 | Nemoralisin C | Others | |
Nemoralisin C shows antiproliferative activity against HepG2, AGS, MCF-7, and A-549 cancer cell lines. | |||
TN6711 | Toralactone | Others , Nrf2 | |
Toralactone is a natural product isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism | |||
T20198 | Potassium gluconate | Kalium-beta,Kalium Gluconate,Kaon elixir,Kaon,Potassium D-gluconate,HSDB 3165,K-Iao | Endogenous Metabolite , Antifungal |
Potassium gluconate (Potassium D-gluconate) is an oxidizing carboxylic acid with oral activity and chelating properties with bactericidal activity. | |||
T8263 | 3,4'-Dihydroxyflavone | Influenza Virus | |
3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid. 3,4'-Dihydroxyflavone (3,4'-DHF) shows antiviral activity against Influenza A virus. | |||
T2737 | Neohesperidin | Hesperetin 7-O-neohesperidoside,NSC 31048 | Antioxidant |
Neohesperidin (NSC-31048) with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model. | |||
T1424 | Ethynyl estradiol | 17α-Ethynylestradiol,Ethinyl Estradiol | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite |
Ethynyl estradiol is a semisynthetic alkylated ESTRADIOL with a 17-alpha-ethinyl substitution. It has high estrogenic potency when administered orally, and is often used as the estrogenic component in ORAL CONTRACEPTIVES... | |||
TN1990 | Norathyriol | Akt , DNA/RNA Synthesis , AMPK , PPAR | |
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability. | |||
T4709 | (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride | D-Mannosamine hydrochloride | Others , Endogenous Metabolite |
(2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride (D-Mannosamine hydrochloride) is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery via M cells ... | |||
T1687 | Doxycycline | Vibramycin,Doxiciclina,Doxytetracycline,Doxycyclinum | MMP , ribosome , Antibacterial , Antibiotic , Parasite |
Doxycycline (Doxiciclina) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline has antibacterial activity and antitumor activity. | |||
T5S2245 | Alisol C 23-acetate | Alisol C monoacetate | Others |
Alisol C 23-acetate (Alisol C monoacetate) is a natural product isolated from Alisma orientale, can significantly and strongly inhibit DTH response after oral administration,has antibacterial activity. | |||
TN2023 | 8-Oxoepiberberine | Oxyepiberberine | Others |
8-Oxoepiberberine (Oxyepiberberine) is an alkaloid metabolite in the plasma after oral administration of Zuojin formula. Zuojin formula is a traditional chinese medicine used to treat gastrointestinal disease. | |||
T1687L | Doxycycline (hyclate) | Doxycycline hydrochloride hemiethanolate hemihydrate,WC2031,Doxycycline hyclate | MMP , ribosome , Antibacterial , Antibiotic |
Doxycycline hyclate (WC2031) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline hyclate has antibacterial activity and antitumor act... | |||
T1508 | Decitabine | Dacogen,NSC 127716,Deoxycytidine,5-Aza-2'-deoxycytidine | Apoptosis , Nucleoside Antimetabolite/Analog , DNA Methyltransferase |
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis... | |||
TJS0928 | Calenduloside E | Silphioside F | Others |
Calenduloside E (Silphioside F) exhibits hypoglycemic activities by suppressing the transfer of glucose from the stomach to the small intestine and by inhibiting glucose transport at the brush border of the small intesti... | |||
T5746 | Dictamine | Dictamnine,Dectamine | Apoptosis , Anti-infection , Antibacterial , Antifungal |
Dictamine (Dectamine) shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma... | |||
TN2031 | γ-Terpinene | Moslene,p-Mentha-1,4-diene,Crithmene | Antioxidant |
γ-Terpinene (p-Mentha-1,4-diene) is a monoterpene compound with high antioxidant properties suitable for oral consumption. It displays direct radical scavenging abilities and is known to be a potent antinociceptive agent... | |||
TN7238L | Sanguinarine citrate | Sanguinarium citrate,Sanguinarin citrate,Pseudochelerythrine citrate | Antibiotic |
Sanguinarine citrate (Pseudochelerythrine chloride) is an alkaloid derived from Sanguinaria Canadensis with antimicrobial, anti-inflammatory, and analgesic activity that is used in the treatment of oral inflammatory dise... | |||
T3400 | Bakuchiol | p38 MAPK , DNA/RNA Synthesis , Autophagy | |
Bakuchiol possesses anti-tumor,and anti-helmenthic properties. It has cytotoxic activity, mainly due to its DNA polymerase1 inhibiting activity. Bakuchiol has anti-bacterial activity against oral pathogens, has great pot... | |||
T1678 | Nystatin | Stamycin,Fungicidin,Nystavescent | Apoptosis , Antibiotic , Antifungal |
Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat skin and oropharyngeal candidiasis. | |||
T5803 | D(-)-Tartaric acid | Others | |
D(-)-Tartaric acid found in many plants, particularly tamarinds and grapes,it is used to generate carbon dioxide through interaction with sodium bicarbonate following oral administration. Carbon dioxide extends the stoma... | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03589 | PsaA Protein, S. oralis, Recombinant (His & Myc) | Streptococcus oralis | E. coli |
Part of an ATP-driven transport system. | |||
TMPY-05081 | Notch 1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair... | |||
TMPY-02785 | Tetranectin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes v... | |||
TMPY-01061 | FGF-10 Protein, Human, Recombinant | Human | E. coli |
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes... | |||
TMPJ-00042 | TSLP Protein, Human, Recombinant | Human | E. coli |
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci... | |||
TMPY-05157 | TGFBR2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma... | |||
TMPY-01882 | HE4 Protein, Human, Recombinant (His) | Human | HEK293 |
WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP ... | |||
TMPY-01912 | Cadherin 17/CDH17 Protein, Human, Recombinant (His) | Human | HEK293 |
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r... | |||
TMPY-05352 | Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r... | |||
TMPY-02919 | Cadherin 17/CDH17 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r... | |||
TMPH-02336 | TAS2R10 Protein, Human, Recombinant (His & KSI) | Human | E. coli |
Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. | |||
TMPY-03225 | VSIG8 Protein, Human, Recombinant (hFc) | Human | HEK293 |
V-set and immunoglobulin domain containing 8 (VSIG8) is essential in hair cycle, oral mucosa, and the nail matrix. Moreover, VSIG8 also has an important role in proper epithelial differentiation and function in the upper... | |||
TMPY-03851 | BPIFB1 Protein, Human, Recombinant (His) | Human | HEK293 |
BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is express... | |||
TMPJ-00157 | CD82 Protein, Human, Recombinant (hFc) | Human | Human Cells |
CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemoki... | |||
TMPH-03155 | Lys-gingipain HG66 Protein, Porphyromonas gingivalis, Recombinant (His & Myc) | Porphyromonas gingivalis | E. coli |
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the fun... | |||
TMPH-03156 | Lys-gingipain Protein, Porphyromonas gingivalis, Recombinant (His & SUMO) | Porphyromonas gingivalis | E. coli |
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the fun... | |||
TMPH-03154 | Lys-gingipain 381 Protein, Porphyromonas gingivalis, Recombinant (His) | Porphyromonas gingivalis | E. coli |
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the fun... | |||
TMPY-01911 | PLA2G1B Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
phospholipase A2, also known as Phosphatidylcholine 2-acylhydrolase 1B, Group IB phospholipase A2, PLA2 and PLA2G1B, is a secreted protein that belongs to the phospholipase A2 family. Phospholipase A2 / PLA2G1B catalyzes... | |||
TMPY-01689 | PLA2G1B Protein, Human, Recombinant (His) | Human | HEK293 |
phospholipase A2, also known as Phosphatidylcholine 2-acylhydrolase 1B, Group IB phospholipase A2, PLA2 and PLA2G1B, is a secreted protein that belongs to the phospholipase A2 family. Phospholipase A2 / PLA2G1B catalyzes... | |||
TMPH-02414 | Lys-gingipain W83 Protein, Porphyromonas gingivalis, Recombinant (His) | Porphyromonas gingivalis | E. coli |
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the fun... | |||
TMPH-02174 | PYCR1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
TMPH-00331 | ALS3 Protein, Candida albicans, Recombinant (B2M & His & Myc) | Candida albicans | E. coli |
Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans... | |||
TMPH-03157 | Fimbrillin Protein, Porphyromonas gingivalis, Recombinant (His & Myc) | Porphyromonas gingivalis | E. coli |
Structural subunit of the major fimbriae. These long, filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbio... | |||
TMPJ-00860 | HTN3 Protein, Human, Recombinant | Human | E. coli |
HTN3 belongs to the histatin/statherin family. Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histat... | |||
TMPY-03971 | Statherin Protein, Human, Recombinant (mFc) | Human | HEK293 |
Statherin, also known as STATH, belongs to the histatin/statherin family. Statherin may play an important role in the maintenance of oral health. It prevents calcium phospate precipitation in saliva, so maintaining a hig... | |||
TMPJ-00160 | EMMPRIN/CD147 Protein, Human, Recombinant (His) | Human | Human Cells |
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane ... | |||
TMPJ-00764 | Catalase/CAT Protein, Human, Recombinant | Human | E. coli |
Catalase (CAT) is a member of the catalase family. It exists as a homotetramer that occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase ... | |||
TMPY-03332 | PRTFDC1 Protein, Human, Recombinant (His) | Human | E. coli |
PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG ... | |||
TMPJ-01207 | UPP1 Protein, Human, Recombinant (His) | Human | E. coli |
Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase. UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The expression levels and the enzymatic activity of UPP1 are higher in h... | |||
TMPJ-01372 | Cornulin Protein, Human, Recombinant (His) | Human | E. coli |
Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-ter... | |||
TMPY-04170 | DEFB1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
The DEFB1 gene, encoding for the constitutively expressed human beta-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been rep... | |||
TMPY-05618 | CXCL14 Protein, Human, Recombinant, Biotinylated | Human | E. coli |
CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is in... | |||
TMPY-03781 | CXCL14 Protein, Human, Recombinant | Human | E. coli |
CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is in... | |||
TMPY-06582 | CXCL14 Protein, Human, Recombinant (His) | Human | E. coli |
CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is in... | |||
TMPY-00001 | CXCL14 Protein, Mouse, Recombinant | Mouse | E. coli |
CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is in... | |||
TMPY-04695 | CCL4 Protein, Rat, Recombinant (His) | Rat | Yeast |
CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment. T... | |||
TMPY-00646 | CCL4 Protein, Human, Recombinant (His) | Human | Yeast |
CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment. T... | |||
TMPJ-01173 | TFF3 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Trefoil factors (TFF) are secretory products of mucin producing cells. They play a key role in the maintenance of the surface integrity of oral mucosa and enhance healing of the gastrointestinal mucosa by a process calle... | |||
TMPY-02391 | SUMO1 Protein, Human, Recombinant (His) | Human | E. coli |
Small ubiquitin-like modifier protein (SUMO) modification is a highly dynamic process, catalyzed by SUMO-specific activating (E1), conjugating (E2) and ligating (E3) enzymes, and reversed by a family of SUMO-specific pro... | |||
TMPY-00415 | Notch 1 Protein, Mouse, Recombinant (hFc) | Mouse | CHO |
NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair... | |||
TMPY-02663 | Notch 1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair... | |||
TMPH-00672 | Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His) | E. coli | E. coli |
Virulence factor that contributes to intimate adherence of enterohemorrhagic E.coli (EHEC) O157:H7 to host cells. Is able to cleave the secreted human mucin 7 (MUC7) and the glycoprotein 340 (DMBT1/GP340). Also cleaves h... | |||
TMPY-02140 | Tetranectin Protein, Human, Recombinant (His) | Human | HEK293 |
Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes v... | |||
TMPY-05508 | TGFBR2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma... | |||
TMPY-03199 | HE4 Protein, Canine, Recombinant (hFc) | Canine | HEK293 |
WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP ... | |||
TMPY-00440 | HE4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP ... | |||
TMPY-03082 | TGFBR2 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma... | |||
TMPY-03171 | TGFBR2 Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma... | |||
TMPY-05810 | TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated | Human | HEK293 |
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma... | |||
TMPY-06645 | Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r... | |||
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Cat No. | Product Name | ||
---|---|---|---|
L9850 | Orally Active Compound Library | 2484 compounds | |
A unique collection of 2484 of orally active compounds for high-throughput screening and high-content screening. | |||
L9610 | Cyclic Peptide Library | 58 compounds | |
58 species of cyclic peptide molecules for high-throughput and high-content screening; | |||
L2170 | Immuno-Oncology Compound Library | 454 compounds | |
A unique collection of 454 compounds acting on immune-oncology therapeutic targets can be used for high throughput and high content screening; |