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Ozoralizumab
🥰Excellent
Catalog No. T77126Cas No. 1167985-17-2
Alias TS-152, ATN-103
Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Ozoralizumab binds human serum albumin and can be used to study rheumatoid arthritis.
Ozoralizumab
Ozoralizumab
🥰Excellent
Purity: 95.6% (SEC-HPLC)
Catalog No. T77126Alias TS-152, ATN-103Cas No. 1167985-17-2
Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Ozoralizumab binds human serum albumin and can be used to study rheumatoid arthritis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $328 | In Stock | |
| 5 mg | $859 | In Stock | |
| 10 mg | $1,270 | In Stock | |
| 25 mg | $1,890 | In Stock | |
| 50 mg | $2,550 | In Stock |
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Concentration:6.19 mg/mL
Purity:95.6% (SEC-HPLC)
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Product Introduction
Bioactivity
Chemical Properties
| Description | Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Ozoralizumab binds human serum albumin and can be used to study rheumatoid arthritis. |
| In vitro | METHODS: Ozoralizumab (ATN-103) (0.1-1000pM) was used to treat L929 cells and its high TNFα neutralizing potency was determined. RESULTS: Ozoralizumab (ATN-103) has high TNFα neutralizing potency, with very similar binding and dissociation properties, and KD values for human TNFα and monkey TNFα are 20.2 pM and 16.1 pM, respectively. [1] |
| In vivo | METHODS: Tg197 mice were injected subcutaneously with 1 mg/kg dose of Ozoralizumab (ATN-103) twice weekly to evaluate the formation of ADA against each anti-TNFα antibody and the effect of long-term administration of these anti-TNFα antibodies on TNFα-mediated TNFα in Tg197 mice. Efficacy of polyarthritis. RESULTS: Ozoralizumab (ATN-103) significantly and comparably reduced arthritis scores. [1] |
| Synonyms | TS-152, ATN-103 |
| Molecular Weight | 38.44 kDa |
| Cas No. | 1167985-17-2 |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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