a-8

A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the formation and blood levels of anti-inflammatory substances such as interleukin 10 receptor and tumor necrosis factor receptor.

A-887826 is a selective, orally bioavailable, and voltage-dependent Na(v1.8) channel blocker (IC50: 11 nM). It attenuates neuropathic tactile allodynia in vivo.

A-803467 is a selective NaV1.8 channel blocker.

A-804598 is a competitive and selective P2X7 receptor antagonist (IC50: 10 nM, rat; 9 nM, mouse; 11 nM, human).

Angiotensin 1 2 + A (2 - 8) Acetate is a Vasoconstrictor.

A-836339 acts as a potent cannabinoid receptor full agonist which has a higher affinity for the peripheral CB2 receptor (Ki = 0.64 nM) over the central CB1 receptor (Ki = 270 nM). It displays analgesic, anti-inflammatory, and anti-hyperalgesic effects in

13-Hydroxylabda-8(17),14-dien-18-oic acid is a useful organic compound for research related to life sciences and the catalog number is T124116.

Junipediol A 8-glucoside is a useful organic compound for research related to life sciences. The catalog number is T125496 and the CAS number is 188894-18-0.

15-Nor-14-oxolabda-8(17),12-dien-18-oic acid is a useful organic compound for research related to life sciences and the catalog number is T126495.

(8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCδ-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.

Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin.

PA-8 is a small molecule receptor antagonist for PACAP Type I (PAC1) that is selective, effective, and orally active. PA-8 inhibits PacAP-induced CREB phosphorylation at PAC1- receptors, but does not inhibit VPAC1- or vpac2 receptors. PA-8 also inhibited PacAP-induced elevation of cAMP levels in vitro (IC50 = 2 nM) and PacAP-induced aversive response and mechanical atopic pain after intrathecal injection in vivo.

Ethyl 8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66942 and the CAS number is 131666-45-0.

Influenza A virus-IN-8 (S5), a macrocyclic peptide, exhibits no cytotoxicity and acts as a potent inhibitor of Influenza A Virus (IAV), demonstrating significant protease stability, with IC50 values of 6.7 nM for H1 and 6.6 nM for H5 variants. It has a high affinity for H1 variants, binding to a conserved region in the HA stem with a dissociation constant (Kd) of 1.0 nM [1].

E-2078, known chemically as (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8), is a stable analog of Dynorphin A (1–8) and functions as a kappa opioid receptor (KOR) agonist [1].

7(8)-Dehydroschisandrol A (Compound 4a), a lignan extracted from Schizandra chinensis Baill, exhibits mild inhibitory activity against stress-induced gastric ulcers [1].

NRMA-8 is a small-molecule nuclear receptor modulator capable of penetrating the brain. It holds potential for research into central nervous system (CNS) diseases, including Alzheimer's disease, Parkinson's disease, demyelinating diseases, and glioblastoma.

Fos-Mea-8 is a useful organic compound for research related to life sciences. The catalog number is TF0020 and the CAS number is 104702-33-2.

HEGA-8 is a useful organic compound for research related to life sciences. The catalog number is TF0025 and the CAS number is 869652-63-1.

C-HEGA-8 is a useful organic compound for research related to life sciences. The catalog number is TF0100 and the CAS number is 603111-75-7.

3beta,7beta,15beta-trihydroxy-11-oxo-lanosta-8-en-24->20 lactone is a natural product

15,16-Epoxy-12R-hydroxylabda-8(17),13(16),14-triene is a natural product for life sciences research. Its catalog number is TN2631 and its CAS number is 61597-55-5.

15,16-Epoxy-12S-hydroxylabda-8(17),13(16),14-triene is a natural product for research related to life sciences. The catalog number is TN2632 and the CAS number is 216011-55-1.

19-[(beta-D-glucopyranosyl)oxy]-19-oxo-ent-labda-8(17),13-dien-16,15-olide is a natural product for research related to life sciences. The catalog number is TN2661 and the CAS number is 919120-78-8.