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Anti-FAK Monoclonal Antibody (2A887)
(Synonyms: PTK2, pp125FAK, FRNK, FAK1, FAK, FADK) Copy Product Info
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Synonyms: PTK2, pp125FAK, FRNK, FAK1, FAK, FADK
Catalog No. TMAT-1223 Copy Product Info
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Anti-FAK Monoclonal Antibody (2A887) is a Mouse antibody targeting FAK. Anti-FAK Monoclonal Antibody (2A887) can be used in IF,FCM.
Anti-FAK Monoclonal Antibody
(2A887)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-FAK Monoclonal Antibody (2A887) is a Mouse antibody targeting FAK. Anti-FAK Monoclonal Antibody (2A887) can be used in IF,FCM. |
| Synonyms | PTK2, pp125FAK, FRNK, FAK1, FAK, FADK |
| Ig Type | IgG1 |
| Clone | 2A887 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. Tissue specificity: Expressed in all organs tested, in lymphoid cell lines, but most abundantly in brain.RD: Focal adhesion kinase 1 (FAK) is a ubiquitously expressed non-receptor protein tyrosine kinase that is concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This cellular localization is directed by a |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human FAK expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PTK2 |
| Gene ID | |
| Protein Name | Focal adhesion kinase 1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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