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Duligotuzumab (Synonyms: RG 7597, MEHD-7945A, Duligotumab)
Catalog No. T9901A-828 Copy Product Info
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Duligotuzumab is a dual-targeting human IgG1 monoclonal antibody that simultaneously binds to both epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3). Duligotuzumab exerts its antitumor effects by blocking these dual signaling pathways and by inducing antibody-dependent cellular cytotoxicity (ADCC), targeting tumors where EGFR/HER3 overexpression correlates with poor prognosis.
Duligotuzumab
Copy Product Info🥰Excellent
Catalog No. T9901A-828
Synonyms RG 7597, MEHD-7945A, Duligotumab
Duligotuzumab is a dual-targeting human IgG1 monoclonal antibody that simultaneously binds to both epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3). Duligotuzumab exerts its antitumor effects by blocking these dual signaling pathways and by inducing antibody-dependent cellular cytotoxicity (ADCC), targeting tumors where EGFR/HER3 overexpression correlates with poor prognosis.
Duligotuzumab
Cas No. 1314238-96-4
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $398 | - | In Stock | |
| 5 mg | $1,037 | - | In Stock | |
| 10 mg | $1,660 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:97.7% (SDS-PAGE); 96.3% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Duligotuzumab is a dual-targeting human IgG1 monoclonal antibody that simultaneously binds to both epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3). Duligotuzumab exerts its antitumor effects by blocking these dual signaling pathways and by inducing antibody-dependent cellular cytotoxicity (ADCC), targeting tumors where EGFR/HER3 overexpression correlates with poor prognosis. |
| Synonyms | RG 7597, MEHD-7945A, Duligotumab |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | ERBB3 & EGFR |
| Molecular Weight | 144.77 kDa |
| Cas No. | 1314238-96-4 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
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