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Anti-RTN3 Monoclonal Antibody (3A899)
(Synonyms: RTN3-A1, NSPLII, NSPL2, HAP, ASYIP) Copy Product Info
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Synonyms: RTN3-A1, NSPLII, NSPL2, HAP, ASYIP
Catalog No. TMAT-0586 Copy Product Info
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Anti-RTN3 Monoclonal Antibody (3A899) is a Mouse antibody targeting RTN3. Anti-RTN3 Monoclonal Antibody (3A899) can be used in IF.
Anti-RTN3 Monoclonal Antibody
(3A899)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-RTN3 Monoclonal Antibody (3A899) is a Mouse antibody targeting RTN3. Anti-RTN3 Monoclonal Antibody (3A899) can be used in IF. |
| Synonyms | RTN3-A1, NSPLII, NSPL2, HAP, ASYIP |
| Ig Type | IgG2a |
| Clone | 3A899 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of RTN3 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | RTN3 |
| Gene ID | |
| Protein Name | Reticulon-3 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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