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Anti-UCP2 Monoclonal Antibody (5B107)
(Synonyms: UCPH, SLC25A8, BMIQ4) Copy Product Info
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Synonyms: UCPH, SLC25A8, BMIQ4
Catalog No. TMAT-1133 Copy Product Info
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Anti-UCP2 Monoclonal Antibody (5B107) is a Mouse antibody targeting UCP2. Anti-UCP2 Monoclonal Antibody (5B107) can be used in IF,FCM.
Anti-UCP2 Monoclonal Antibody
(5B107)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-UCP2 Monoclonal Antibody (5B107) is a Mouse antibody targeting UCP2. Anti-UCP2 Monoclonal Antibody (5B107) can be used in IF,FCM. |
| Synonyms | UCPH, SLC25A8, BMIQ4 |
| Ig Type | IgG2a |
| Clone | 5B107 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human UCP2 (AA: 1-309) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | UCP2 |
| Gene ID | |
| Protein Name | Dicarboxylate carrier SLC25A8 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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