Shopping Cart
Remove All
Your shopping cart is currently empty
Abelacimab
(Synonyms: MAA868, MAA 868) Copy Product Info
🥰Excellent
Synonyms: MAA868, MAA 868
Catalog No. T76894 Copy Product Info
🥰Excellent
Abelacimab (MAA868), a fully human IgG1 monoclonal antibody that binds to and blocks the activation of FXI, is an anticoagulant used in the study of thromboembolic diseases.
Cas No. 2098724-83-3
Customer service consultation
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $228 | In Stock | In Stock | |
| 5 mg | $629 | In Stock | - | |
| 10 mg | $993 | 7-10 days | 7-10 days | |
| 25 mg | $1,470 | 7-10 days | 7-10 days | |
| 50 mg | $1,980 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
Select Batch
Purity:94.9% (SDS-PAGE); 99.1% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Abelacimab (MAA868), a fully human IgG1 monoclonal antibody that binds to and blocks the activation of FXI, is an anticoagulant used in the study of thromboembolic diseases. |
| In vitro | Abelacimab prolonged clotting time and decreased human plasma thrombin levels in a concentration-dependent manner over a concentration range of 0.0001 to 1 μM. [1] |
| In vivo | Subcutaneous injections of 3-30 mg/kg Abelacimab , days 1, 85, and 114, demonstrated potent and long-lasting anticoagulant effects in crab-eating monkeys, significantly prolonged the aPTT, and had a favorable safety profile, with no significant signs of toxicity or bleeding observed. In addition, intravenous, 0.6 mg/kg Abelacimab also demonstrated excellent anticoagulant activity in the FXI-/- C57BL/6 mouse model of ferric chloride-induced thrombosis, preventing carotid artery occlusion. [1] |
| Synonyms | MAA868, MAA 868 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | F11/Factor XI |
| Molecular Weight | 144.32 kDa |
| Cas No. | 2098724-83-3 |
| Isotype | IgG1 |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Calculator
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Preview
Related Tags: Abelacimab chemical structure | Abelacimab in vivo | Abelacimab in vitro | Abelacimab molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.