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Synonyms: TCF7L3, TCF1ALPHA, TCF10, LEF-1
Anti-LEF1 Monoclonal Antibody
(2A878)

| Description | Anti-LEF1 Monoclonal Antibody (2A878) is a Mouse antibody targeting LEF1. Anti-LEF1 Monoclonal Antibody (2A878) can be used in WB,IHC. |
| Synonyms | TCF7L3, TCF1ALPHA, TCF10, LEF-1 |
| Ig Type | IgG1 |
| Clone | 2A878 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human LEF1 (AA: 33-138) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | LEF1 |
| Gene ID | |
| Protein Name | Lymphoid enhancer-binding factor 1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 44.2 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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