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Antibacterial

Antibacterial usually refers to an antibiotic, a principal type of antimicrobial agent used mainly against bacteria; it may kill or inhibit them.

  • G-418 disulfate
    T6512108321-42-2
    G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, an inhibitor of protein synthesis with eukaryotic selectivity. G-418 disulfate blocks peptide synthesis by inhibiting peptide chain elongation.
    • $33.6
    • $42
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  • Durlobactam sodium salt
    T111251467157-21-6
    Durlobactam sodium salt (ETX2514 sodium salt) is an inhibitor of β-lactamase with IC50 values of 4 nM, 14 nM, and 190 nM for Class A KPC-2, Class C AmpC, and Class D OXA-24, respectively. Durlobactam sodium salt can be used in studies about drug-resistant Gram-negative bacteria including Acinetobacter baumannii.
    • $168
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  • Nigericin sodium salt
    T309228643-80-3
    Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which inhibits Golgi function and suppresses the growth of Gram-positive bacteria.
    • $31
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  • Avibactam sodium
    T42011192491-61-4
    Avibactam sodium (NXL-104) is a reversible β-lactamase inhibitor (IC50: 8 80 38 nM, for TEM-1 P99 KPC-2 β-lactamases).
    • $35
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    TargetMol | Inhibitor Hot
  • Doxycycline
    T1687564-25-0
    Doxycycline (Doxiciclina) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline has antibacterial activity and antitumor activity.
    • $45
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  • Abietic Acid
    T3090514-10-3
    Abietic Acid (Sylvic acid) is the primary component of resin acid isolated from rosin.
    • $83
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  • Tunicamycin
    T1322911089-65-9
    Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT). Tunicamycin has antitumor activity, as well as anti-bacterial, anti-fungal, and anti-viral activity.
    • $105
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  • Hypericin
    T6S0923548-04-9
    1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL-mediated osteoclastogenesis via affecting ERK signalling in vitro and suppresses wear particle-induced osteolysis in vivo.
    • $52
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  • Anisomycin
    T675822862-76-6
    Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
    • $46
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  • Puromycin dihydrochloride
    T221958-58-2
    Puromycin dihydrochloride (CL13900 dihydrochloride) is a cinnamamide adenosine antibiotic and an inhibitor of protein synthesis. Puromycin dihydrochloride inhibits protein synthesis by binding to RNA and has antitumor and antitrypanosomal activity.
    • $31.2
    • $39
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  • 2-Hydroxy-1-methoxyanthraquinone
    TN12096170-06-5
    2-Hydroxy-1-methoxyanthraquinone (Alizarin 1-methyl ether) is a natural product isolated from Morinda lucida Benth. (Rubiaceae) with antibacterial activity.
    • $113
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  • Doxorubicin hydrochloride
    T102025316-40-9
    Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitumor activity. Doxorubicin hydrochloride reduces the phosphorylation of AMPK and its downstream target protein acetyl coenzyme A carboxylase, and induces apoptosis and autophagy.
    • $34
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  • Dexamethasone
    T107650-02-2
    Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and an IL receptor modulator. Dexamethasone has anti-inflammatory and immunosuppressive activity and induces autophagy. Dexamethasone inhibits LPS-induced inflammatory responses in macrophages.
    • $45
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  • Bafilomycin A1
    T674088899-55-2
    Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase inhibitor (IC50=0.44 nM) that is specific and reversible. Bafilomycin A1 is an inhibitor of the late phase of autophagy, blocking the fusion of autophagosomes with lysosomes. Bafilomycin A1 also induces apoptosis.
    • $287
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  • Cefonicid sodium
    T122861270-78-8
    Cefonicid binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Cefonicid sodium (Monocid sodium) is the sodium salt form of cefonicid, a semisynthetic second-generation cephalosporin with antibacterial activity. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
    • $40
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  • Tigemonam
    T13926102507-71-1In house
    Tigemonam is a monobactam. Tigemonam has potent activity against Gram-negative aerobic bacterial pathogens.
    • $1,320
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  • Streptozocin
    T150718883-66-4
    Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used in the construction of animal models of type 1 diabetes. The product is unstable in solution and is recommended to be dispensed now.
    • $30
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  • Hypocrellin A
    T577177029-83-5
    Hypocrellin A is PKC inhibitor, has light-induced antitumor,antifungal and antiviral activities, it also exerts immunomodulatory effects on MHC-restricted presentation of antigen.
    • $47
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  • Ceftobiprole
    TQ0077209467-52-7
    Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA; MIC90: 2 μg mL).
    • $148
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  • Staurosporine
    T668062996-74-1
    Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6 15 2 3 3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces apoptosis.
    • $56
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  • Nadifloxacin
    T1466124858-35-1
    Nadifloxacin (OPC7251) has been used in trials studying the treatment of Acne Vulgaris.
    • $33
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  • (E)-Methyl 4-coumarate
    T373319367-38-5
    Methyl (E)-4-hydroxycinnamatee is found in several plants such as onion or Morinda citrifolia. It induces apoptosis in combination with Carnosic Acid and kills acute myeloid leukemia cells. It has antioxidant and antibacterial activity.
    • $42
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  • Demeclocycline hydrochloride
    T140064-73-3
    Demeclocycline hydrochloride (Declomycin) is a TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time.
    • $30
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  • Mupirocin calcium hydrate
    T8148115074-43-6
    Mupirocin calcium hydrate is an antibiotic produced by Pseudomonas fluorescens, showed a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria
    • $97
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  • Chloroxine
    T0500773-76-2
    Chloroxine (Capitrol) is a synthetic quinoline derivative with antibacterial activity. Although the mechanism of action is not fully understood, topical administration of chloroxine diminishes mitotic activity in the epidermis, thereby reducing excessive scaling associated with dandruff or seborrheic dermatitis of the scalp, including psoriasis and eczema.
    • $43
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  • Ectoine
    T403896702-03-3
    Ectoine (L-Ectoine) is an osmoprotectant in a variety of microorganisms including halophilic and heterotrophic bacteria and non-halophilic bacteria such as the Streptomyces species, as well as E.coli.
    • $45
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  • Glycitin
    T282040246-10-4
    Glycitin (Glycitein 7-O-β-glucoside), a natural isoflavone isolated from legumes, can promote the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover.
    • $60
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  • Sodium Houttuyfonate
    TN528483766-73-8
    Sodium Houttuyfonate (Houttuynin sodium bisulfite), the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.
    • $45
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  • Thiobarbituric acid
    T20550504-17-6
    Thiobarbituric acid (NSC-4733) has Antibacterial Activity.
    • $37
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  • Closantel
    T023757808-65-8
    Closantel (R-31520), a salicylanilide anthelmintic compound, shows different anthelmintic spectra and obvious toxicity in mammals.
    • $34
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  • Sulfachloropyridazine
    T218480-32-0
    Sulfachloropyridazine (Sulfachlorpyridazine) is a sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
    • $50
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  • Etoposide
    T013233419-42-0
    Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM). Etoposide has antitumor activity and induces apoptosis and autophagy.
    • $33
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  • Neomycin sulfate
    T09501405-10-3
    Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert antimicrobial activity. Neomycin sulfate is commonly used to screen prokaryotic and eukaryotic cells for Neo resistance genes.
    • $43
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    TargetMol | Citations Cited
  • Taurolidine
    T753319388-87-5
    Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity.
    • $47
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  • Oridonin
    T279028957-04-2
    Oridonin (NSC-250682) is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2.
    • $45
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  • DDAC
    T643467173-51-5
    DDAC (Quaternium 12), also known as Didecyldimethylammonium chloride, is a dialkyl-quaternary ammonium compound widely utilized in various products due to its bactericidal, virucidal, and fungicidal characteristics.
    • $39
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  • Tubercidin
    T700469-33-0
    Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities.
    • $48
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  • Methyl indole-3-carboxylate
    T5868942-24-5
    Methyl indole-3-carboxylate (Methyl 3-indolecarboxylate) is a natural product isolated from Heracleum candicans.
    • $42
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  • Hygromycin B
    T102231282-04-9
    Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis by interfering with translocation and causing mistranslation of the 70S ribosome. Hygromycin B can be used to screen prokaryotic or eukaryotic cells transfected with hph or hyg resistance genes.
    • $48
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  • Sulbenicillin disodium
    T806628002-18-8
    Sulbenicillin disodium (Sulbenicillin Sodium) is a penicillin antibiotic,is a Penicillin antibiotic with antibacterial activity
    • $50
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  • Thiamine monochloride
    T2O274159-43-8
    Thiamine monochloride (Vitamin B1) is an essential vitamin with erythropoietic, glucose-regulatory, antioxidant, and mood-regulatory properties.Thiamine monochloride inhibits lead-induced lipid peroxidation, thereby preventing lead poisoning.Thiamine monochloride plays an important role in the production of energy by the cells that ingest the food, and enhances normal Thiamine monochloride plays an important role in the energy production of ingested food cells and enhances normal neuronal activity.
    • $41
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  • Kasugamycin hydrochloride hydrate
    T8404200132-83-8
    Kasugamycin hydrochloride hydrate (Ksg (hydrochloride hydrate))(Ksg) specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs. Ksg inhibition is thought to occur by direct competition with initiator transfer RNA
    • $29
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  • Hederacoside C
    T337014216-03-6
    Hederacoside C (Hederasaponin C) is expectorant for Cold and cough relief, Bronchitis.
    • $42
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  • Aucubin
    T3416479-98-1
    Aucubin (Rhinanthin) is an iridoid glycoside with anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities.
    • $97
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  • Sulfamethoxazole
    T0885723-46-6
    Sulfamethoxazole (STX 608) is a Sulfonamide Antimicrobial. The mechanism of action of sulfamethoxazole is as a Cytochrome P450 2C9 Inhibitor. The chemical classification of sulfamethoxazole is Sulfonamides.
    • $46
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  • Phenoxyethanol
    T20293122-99-6
    Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.
    • $48
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  • Tricyclazole
    T595541814-78-2
    Tricyclazole (Tricyclazol) is a pentaketide-derived melanin biosynthesis inhibitor. Tricyclazole is a a unique fungicide for control of Pyricularia oryzae on rice.
    • $41
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  • Tetracycline
    T0912L60-54-8
    Tetracycline (Tetracyclin) is a naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.
    • $33
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  • Colistin methanesulfonate sodium salt
    T215188068-28-8
    Colistin methanesulfonate sodium salt (Colistimethate Sodium) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.
    • $41
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  • Kanamycin sulfate
    T079325389-94-0
    Kanamycin sulfate (Kanamycin monosulfate) is an aminoglycoside bacteriocidal antibiotic.
    • $41
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