5a

5a is an agonist of 5-HT4R partial. It displayed cognition-enhancing properties in animal models.

5a,9-dimethyl-3-methylidene-2H,3H,3aH,4H,5H,5aH,8H,9bH-naphtho[1,2-b]furan-2,8-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol is a useful organic compound for research related to life sciences and the catalog number is T66653.

(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane is a useful organic compound for research related to life sciences. The catalog number is T66654 and the CAS number is 119302-24-8.

Apo A-I mimetic 5A peptide is a synthetic peptide molecule designed based on the structure and function of naturally occurring apolipoprotein A-I (Apo A-I). It facilitates the efflux of cholesterol from inside cells, helping to reduce intracellular cholesterol accumulation. Additionally, Apo A-I mimetic 5A peptide exhibits anti-inflammatory properties, lowering inflammatory markers in blood and tissues. This peptide is used in cardiovascular disease research.

5a-Pregnane-3,20-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone.

KDM5A-IN-1 is an orally available, potent and selective inhibitor of the pan-histidine lysine demethylase 5 KDM5, inhibiting KDM5A, KDM5B, and KDM5C with IC50 values of 45 nM, 56 nM, and 55 nM, respectively.KDM5A-IN-1 inhibits PC9 H3K4Me3, and may be useful in cancer research.

2-5A (5'-O-Triphosphoryladenylyl-(2'→5')-adenylyl-(2'→5')-adenosine) pentasodium is a 5'-triphosphorylated (2',5') oligo-adenylate. Acting as an immune mediator, 2-5A pentasodium enhances the activity of RNase L. It degrades viral mRNA and inhibits protein synthesis by binding to RNase L and activating its ribonuclease function. This compound is useful in research related to respiratory syncytial virus (RSV) and cancer.

2-5A is a 5'-triphosphorylated (2',5') oligoadenylate. It acts as an immune messenger capable of enhancing RNase L immunity. By binding to RNase L and activating its endoribonuclease activity, 2-5A degrades viral mRNA and inhibits protein synthesis. This compound is useful in research on respiratory syncytial virus (RSV) and cancer.

TCS JNK 5a (SC202671) is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).

DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation. It is utilized in diabetes-related research [1].

1b-Benzoyl-8a-cinnamoyl-4a,5a-dihydroxydihydroagarofuran is a sesquiterpenoid isolated from the root bark of Tripterygium hypoglaucum, characterized by benzoyl and cinnamoyl groups [1].

H2S Donor 5a is a H2S donor that could mimic the slow and continuous H(2)S generation process.

7-hydroxy-2,5b,9,9,11a-pentamethyl-2,3,4,5,5a,5b,6,9,9a,10,11,11a-dodecahydro-1,12-dioxatetraphene-4,6-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

2,5b,9,9,11a-pentamethyl-2,3,4,5,5a,5b,6,9,9a,10,11,11a-dodecahydro-1,12-dioxatetraphene-4,6-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

3a,8-dihydroxy-3,5a,9-trimethyl-2H,3H,3aH,4H,5H,5aH,6H,7H,8H,9bH-naphtho[1,2-b]furan-2-one is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

6-hydroxy-3,5a,9-trimethyl-2H,3H,3aH,4H,5H,5aH,6H,7H,9aH,9bH-naphtho[1,2-b]furan-2-one is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

9a-hydroxy-2,5b,9,9,11a-pentamethyl-2,3,4,5,5a,5b,6,9,9a,10,11,11a-dodecahydro-1,12-dioxatetraphene-4,6-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

9a-methyl-3,4'-dioxo-3,4,5,5a,7,8,9,9a-octahydro-1H-spiro[naphtho[1,2-c]furan-6,3'-oxetan]-5-yl acetate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

3a-hydroxy-3,5a,9-trimethyl-2H,3H,3aH,4H,5H,5aH,6H,7H,8H,9bH-naphtho[1,2-b]furan-2,8-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

9a-hydroxy-2,5b,9,9,11a-pentamethyl-4,5,5a,5b,6,9,9a,10,11,11a-decahydro-1,12-dioxatetraphene-4,6-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.

Abiraterone Metabolite 1, a 5β-reduced derivative of abiraterone, acts by inhibiting CYP17A1, thereby blocking androgen synthesis and extending survival in prostate cancer patients.

5α-Cholestan-3-one (Coprostanone) is an intermediate product in cholesterol metabolism, which is elevated in the case of cerebrotendinous xanthomatosis. Within the cell, It is primarily located in the membrane (predicted from logP).