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Anti-CD105 Antibody (2R972)
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Catalog No. TMAB-03815
Anti-CD105 Antibody (2R972) is a Mouse antibody targeting CD105. Anti-CD105 Antibody (2R972) can be used in IHC-P,IHC-Fr,IF.
Anti-CD105 Antibody (2R972)
Anti-CD105 Antibody (2R972)
Copy Product Info😃Good
Catalog No. TMAB-03815
Anti-CD105 Antibody (2R972) is a Mouse antibody targeting CD105. Anti-CD105 Antibody (2R972) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-CD105 Antibody (2R972) is a Mouse antibody targeting CD105. Anti-CD105 Antibody (2R972) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG1 |
| Clone | 2R972 |
| Reactivity | Human |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD105Monoclonal Antibody, Unconjugated (ascites of TMAB-03815) at 1:1500 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Human Ovarian Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD105Monoclonal Antibody, Unconjugated (ascites of TMAB-03815) at 1:1500 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD105Monoclonal Antibody, Unconjugated (ascites of TMAB-03815) at 1:1500 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD105Monoclonal Antibody, Unconjugated (ascites of TMAB-03815) at 1:1500 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Human Breast Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD105Monoclonal Antibody, Unconjugated (ascites of TMAB-03815) at 1:1500 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining. 6. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD105Monoclonal Antibody, Unconjugated (ascites of TMAB-03815) at 1:1500 overnight at 4°C, followed by conjugation to the AffiniPure Goat Anti-Mouse IgG H&L-HRP and DAB staining. 7. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CD105 Monoclonal Antibody, Unconjugated (TMAB-03815) at 1: 200 overnight at 4°C. Followed by conjugated Goat Anti-Mouse IgG antibody (green), DAPI (blue) was used to stain the cell nuclei. |
| Application | |
| Recommended Dose | IHC-P: 1:200-2000; IHC-Fr: 1:200-2000; IF: 1:200-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Endoglin is restricted to endothelial cells in all tissues except bone marrow. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013] |
| Immunogen | Recombinant Protein: human CD105 |
| Antigen Species | Human |
| Gene Name | ENG |
| Gene ID | |
| Protein Name | Endoglin |
| Uniprot ID | |
| Function | Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. |
| Molecular Weight | Theoretical: 70 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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