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Anti-UCHL1/PGP9.5 Antibody (2J681)
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Catalog No. TMAB-13964
Anti-UCHL1/PGP9.5 Antibody (2J681) is a Mouse antibody targeting UCHL1/PGP9.5. Anti-UCHL1/PGP9.5 Antibody (2J681) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-UCHL1/PGP9.5 Antibody (2J681)
Anti-UCHL1/PGP9.5 Antibody (2J681)
😃Good
Catalog No. TMAB-13964
Anti-UCHL1/PGP9.5 Antibody (2J681) is a Mouse antibody targeting UCHL1/PGP9.5. Anti-UCHL1/PGP9.5 Antibody (2J681) can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-UCHL1/PGP9.5 Antibody (2J681) is a Mouse antibody targeting UCHL1/PGP9.5. Anti-UCHL1/PGP9.5 Antibody (2J681) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG1 |
| Clone | 2J681 |
| Reactivity | Human (predicted:Mouse,Rat,Pig,Cow,Monkey,Xenopus) |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC-P: 1:20-50; IHC-Fr: 1:400-800; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm. Endoplasmic reticulum membrane. About 30% of total UCHL1 is associated with membranes in brain. |
| Tissue Specificity | Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | catalyzes the hydrolysis of ubiquitin carboxy-terminal thiolesters to form ubiquitin and a thiol; may play a role in neuropathic pain [RGD]. Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients. |
| Immunogen | KLH conjugated synthetic peptide: human UCHL1/PGP9.5 |
| Antigen Species | Human |
| Gene Name | UCHL1 |
| Gene ID | |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
| Uniprot ID | |
| Function | Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity. |
| Molecular Weight | Theoretical: 25 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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