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3β-Androstenol
(Synonyms: Androst-16-en-3-ol, 5α-androst-16-en-3β-ol) Copy Product Info
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Synonyms: Androst-16-en-3-ol, 5α-androst-16-en-3β-ol
Catalog No. TN13590 Copy Product Info
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3β-Androstenol is a natural steroidal compound found in biological samples such as boar testicles and human sweat. It is an important pheromone-related metabolite in research on pheromones, physiological metabolism, and neuropharmacology. As an endogenous neurosteroid, 3β-Androstenol acts as a positive allosteric modulator of GABAA receptors and has demonstrated anxiolytic, antidepressant, and anticonvulsant activity in animal studies.
Cas No. 7148-51-8
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 mg | $50 | Inquiry | Inquiry | |
| 10 mg | $70 | Inquiry | Inquiry | |
| 25 mg | $113 | Inquiry | Inquiry | |
| 50 mg | $163 | Inquiry | Inquiry | |
| 100 mg | $239 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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Custom-made molecule. TargetMol’s expert synthesis team delivers cost-effective solutions. Contact us for inquiries. Committed to serving you.However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 3β-Androstenol is a natural steroidal compound found in biological samples such as boar testicles and human sweat. It is an important pheromone-related metabolite in research on pheromones, physiological metabolism, and neuropharmacology. As an endogenous neurosteroid, 3β-Androstenol acts as a positive allosteric modulator of GABAA receptors and has demonstrated anxiolytic, antidepressant, and anticonvulsant activity in animal studies. |
| In vitro | Method: Mouse cerebellar granule cell cultures were treated with 3β-Androstenol (1000 nM and 3000 nM) co-applied with 0.25 μM GABA, and changes in GABA-activated currents were detected using whole-cell patch-clamp recording. Result: 3β-Androstenol at concentrations of 1000 nM and 3000 nM did not significantly enhance GABA-activated currents [1]. |
| In vivo | Method: In a PTZ (pentylenetetrazole) seizure model in mice, 3β-Androstenol (100 mg/kg) was administered intraperitoneally 15 min prior to PTZ injection, and protection against clonic seizures was observed over a 30-min period. Result: 3β-Androstenol at a dose of 100 mg/kg failed to protect any animals from PTZ-induced seizures [1]. |
| Synonyms | Androst-16-en-3-ol, 5α-androst-16-en-3β-ol |
| Molecular Weight | 274.44 |
| Formula | C19H30O |
| Cas No. | 7148-51-8 |
| Smiles | C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)C=CC4)[H])(CC[C@]1(C[C@@H](O)CC2)[H])[H])[H] |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: 3β-Androstenol chemical structure | 3β-Androstenol in vivo | 3β-Androstenol in vitro | 3β-Androstenol formula | 3β-Androstenol molecular weight
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