Shopping Cart

Your shopping cart is currently empty

HexylHIBO

Name: HexylHIBO
Brand: TargetMol
SKU: T22840
Price: 61 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. T22840Cas No. 334887-43-3

HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.

HexylHIBO

😃Good

Purity: 99.55%

Catalog No. T22840Cas No. 334887-43-3

HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$61	-	In Stock
5 mg	$147	-	In Stock
10 mg	$218	-	In Stock
25 mg	$513	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.55%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.
Targets&IC50	mGlu1a:140 μM(Kb), mGlu5a:110 μM(Kb)

Chemical Properties

Molecular Weight	256.3
Formula	C₁₂H₂₀N₂O₄
Cas No.	334887-43-3
Smiles	C(CCCCC)C1=C(CC(C(O)=O)N)ONC1=O
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

1eq. NaOH: 18 mg/mL (70.23 mM), Sonication is recommended.

Solution Preparation Table

1eq. NaOH

	1mg	5mg	10mg	50mg
1 mM	3.9017 mL	19.5084 mL	39.0168 mL	195.0839 mL
5 mM	0.7803 mL	3.9017 mL	7.8034 mL	39.0168 mL
10 mM	0.3902 mL	1.9508 mL	3.9017 mL	19.5084 mL
20 mM	0.1951 mL	0.9754 mL	1.9508 mL	9.7542 mL
50 mM	0.0780 mL	0.3902 mL	0.7803 mL	3.9017 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc