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Synonyms: STAT5, MGF
Anti-STAT5A Monoclonal Antibody
(6L933)

| Description | Anti-STAT5A Monoclonal Antibody (6L933) is a Mouse antibody targeting STAT5A. Anti-STAT5A Monoclonal Antibody (6L933) can be used in WB,IHC,IF,FCM. |
| Synonyms | STAT5, MGF |
| Ig Type | IgG1 |
| Clone | 6L933 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/50-1/200; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human STAT5A (AA: 583-794 ) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | STAT5A |
| Gene ID | |
| Protein Name | Signal transducer and activator of transcription 5A |
| Uniprot ID |
| Molecular Weight | Theoretical: 90.6 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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