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Anti-STAT5A Monoclonal Antibody (6L933)

(Synonyms: STAT5, MGF) Copy Product Info
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Synonyms: STAT5, MGF

Catalog No. TMAT-1026 Copy Product Info
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Anti-STAT5A Monoclonal Antibody (6L933) is a Mouse antibody targeting STAT5A. Anti-STAT5A Monoclonal Antibody (6L933) can be used in WB,IHC,IF,FCM.

Anti-STAT5A Monoclonal Antibody
(6L933)

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Product Introduction

Bioactivity
Description
Anti-STAT5A Monoclonal Antibody (6L933) is a Mouse antibody targeting STAT5A. Anti-STAT5A Monoclonal Antibody (6L933) can be used in WB,IHC,IF,FCM.
SynonymsSTAT5, MGF
Ig Type
IgG1
Clone
6L933
Reactivity
Human
Application
Recommended Dose
WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/50-1/200; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human STAT5A (AA: 583-794 ) expressed in E. Coli.
Antigen Species
Human
Gene Name
STAT5A
Gene ID
Protein Name
Signal transducer and activator of transcription 5A
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 90.6 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-STAT5A Monoclonal Antibody (6L933) molecular weight