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Anti-mouse CD25 Antibody (8I40)
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Catalog No. TMAB-08952
Anti-mouse CD25 Antibody (8I40) is a Rat antibody targeting mouse CD25. Anti-mouse CD25 Antibody (8I40) can be used in FCM.
Anti-mouse CD25 Antibody (8I40)
Anti-mouse CD25 Antibody (8I40)
Copy Product Info😃Good
Catalog No. TMAB-08952
Anti-mouse CD25 Antibody (8I40) is a Rat antibody targeting mouse CD25. Anti-mouse CD25 Antibody (8I40) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $352 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-mouse CD25 Antibody (8I40) is a Rat antibody targeting mouse CD25. Anti-mouse CD25 Antibody (8I40) can be used in FCM. |
| Ig Type | Rat IgG1, λ |
| Clone | 8I40 |
| Reactivity | Mouse |
| Verified Activity | Blank control: Ctll-2. Primary Antibody (green line): Rabbit Anti-mouse CD25 antibody (TMAB-08952) Dilution: 1 μg/Test; Secondary Antibody (white blue line) : Goat anti-rat IgG-FITC Dilution: 0.5 μg/Test. Isotype control (orange line): Normal Rat IgG Protocol The cells were incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed. |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Rat |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020] |
| Gene Name | IL2RA |
| Gene ID | |
| Protein Name | Interleukin-2 receptor subunit alpha |
| Function | Receptor for interleukin-2. |
| Molecular Weight | Theoretical: 28 kDa. Actual: 55 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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