autophagy — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9181	Autophagy-IN-A9		Others
	Autophagy-IN-A9 is a bioactive chemical.		Others
T38977	Autophagy-IN-C1	Autophagy-IN-C1
	Autophagy-IN-C1 is a cinchona alkaloid derivative containing urea. Autophagy-IN-C1 not only induces apoptosis but also blocks autophagy in hepatocellular carcinoma (HCC) cells.
T63744	Autophagy inducer 4
	Autophagy inducer 4 is a Mannich base derivative based on Magnolol and can be used as an anticancer agent. autophagy inducer 4 induces autophagy and thus inhibits cancer cells. autophagy inducer 4 is 76 times more toxic ...
T60749	Autophagy-IN-2
	Autophagy-IN-2 (Compound 7h) is an inhibitor of autophagic flux which induces cancer cell apoptosis and can be used for the research of triple-negative breast cancer [1].
T61580	Autophagy inducer 3
	Autophagy Inducer 3 is a chemical compound that exhibits autophagy-induced activity, specifically inducing robust autophagic cell death in various cancer cells while sparing normal cells. This compound induces lethal aut...
T62331	Autophagy-IN-1
	Autophagy-IN-1 is a potent inhibitor of autophagy/mitophagy, blocking autophagosomal-lysosomal fusion in cancer cells while selectively increasing autophagic flux. Autophagy-IN-1 significantly inhibits tumour growth in t...
T28001	MDK-6983	MDK-6983,Compound 6k,Autophagy inhibitor 6k,MDK6983	Autophagy
	MDK-6983 (MDK-6983) is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.		Autophagy
T26683	AUTEN-67	Autophagy enhancer 67,MTMR14 inhibitor,AUTEN67
	AUTEN-67 is a specific inhibitor of MTMR14 and autophagy enhancer with potent antiaging and neuroprotective effects. AUTEN-67 also delays the onset and decreases the severity of Huntington's disease.
T14346	Aumitin		Others , Autophagy
	Aumitin is a diaminopyrimidine-based autophagy inhibitor. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1], and it inhibits mitochondrial re...		Others , Autophagy
T5763	Sedanolide		Others , Autophagy
	Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery.		Others , Autophagy
T6468	D-glutamine		Mitophagy , Ferroptosis , Endogenous Metabolite , GluR , Autophagy
	D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
T11142	EACC		Autophagy
	EACC, a reversible autophagy inhibitor, selectively impedes Stx17, an autophagosome-specific SNARE, from translocating, hence obstructing the fusion between autophagosomes and lysosomes. This compound effectively halts a...		Autophagy
T5S1287	Ligustilide		Apoptosis , Autophagy
	3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.		Apoptosis , Autophagy
T5793	Britannin		Apoptosis , AMPK , Autophagy
	Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.		Apoptosis , AMPK , Autophagy
T1554	Iohexol		Mitophagy , Autophagy
	Iohexol is a contrast agent. The osmolality of iohexol ranges from 322 mOsm/kg-approximately 1.1 times that of blood plasma-to 844 mOsm/kg, almost three times that of blood.		Mitophagy , Autophagy
T5211	NSC 185058	NSC185058	Cysteine Protease , Autophagy
	NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.		Cysteine Protease , Autophagy
T5S1099	Liensinine		Apoptosis , Mitophagy , Others , Autophagy
	1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.		Apoptosis , Mitophagy , Others , Autophagy
T0595	Naringin	Naringoside	Mitophagy , P450 , Endogenous Metabolite , Autophagy
	Naringin (Naringoside), a flavanone glycoside, exerts various of pharmacological effects such as blood lipid lowering, antioxidant activity, anticancer activity, and inhibition of cytochrome P450 enzymes.		Mitophagy , P450 , Endogenous Metabolite , Autophagy
TN1140	Onjisaponin B		AMPK , mTOR , Autophagy
	Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parki...		AMPK , mTOR , Autophagy
T3400	Bakuchiol		p38 MAPK , DNA/RNA Synthesis , Autophagy
	Bakuchiol possesses anti-tumor,and anti-helmenthic properties. It has cytotoxic activity, mainly due to its DNA polymerase1 inhibiting activity. Bakuchiol has anti-bacterial activity against oral pathogens, has great pot...		p38 MAPK , DNA/RNA Synthesis , Autophagy