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Search Results for " autophagy "

20

Compounds

Cat No. Product Name Synonyms Targets
T9181 Autophagy-IN-A9 Others
Autophagy-IN-A9 is a bioactive chemical.
T38977 Autophagy-IN-C1 Autophagy-IN-C1
Autophagy-IN-C1 is a cinchona alkaloid derivative containing urea. Autophagy-IN-C1 not only induces apoptosis but also blocks autophagy in hepatocellular carcinoma (HCC) cells.
T63744 Autophagy inducer 4
Autophagy inducer 4 is a Mannich base derivative based on Magnolol and can be used as an anticancer agent. autophagy inducer 4 induces autophagy and thus inhibits cancer cells. autophagy inducer 4 is 76 times more toxic ...
T60749 Autophagy-IN-2
Autophagy-IN-2 (Compound 7h) is an inhibitor of autophagic flux which induces cancer cell apoptosis and can be used for the research of triple-negative breast cancer [1].
T61580 Autophagy inducer 3
Autophagy Inducer 3 is a chemical compound that exhibits autophagy-induced activity, specifically inducing robust autophagic cell death in various cancer cells while sparing normal cells. This compound induces lethal aut...
T62331 Autophagy-IN-1
Autophagy-IN-1 is a potent inhibitor of autophagy/mitophagy, blocking autophagosomal-lysosomal fusion in cancer cells while selectively increasing autophagic flux. Autophagy-IN-1 significantly inhibits tumour growth in t...
T28001 MDK-6983 MDK-6983,Compound 6k,Autophagy inhibitor 6k,MDK6983 Autophagy
MDK-6983 (MDK-6983) is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.
T26683 AUTEN-67 Autophagy enhancer 67,MTMR14 inhibitor,AUTEN67
AUTEN-67 is a specific inhibitor of MTMR14 and autophagy enhancer with potent antiaging and neuroprotective effects. AUTEN-67 also delays the onset and decreases the severity of Huntington's disease.
T14346 Aumitin Others , Autophagy
Aumitin is a diaminopyrimidine-based autophagy inhibitor. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1], and it inhibits mitochondrial re...
T5763 Sedanolide Others , Autophagy
Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery.
T6468 D-glutamine Mitophagy , Ferroptosis , Endogenous Metabolite , GluR , Autophagy
D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
T11142 EACC Autophagy
EACC, a reversible autophagy inhibitor, selectively impedes Stx17, an autophagosome-specific SNARE, from translocating, hence obstructing the fusion between autophagosomes and lysosomes. This compound effectively halts a...
T5S1287 Ligustilide Apoptosis , Autophagy
3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.
T5793 Britannin Apoptosis , AMPK , Autophagy
Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.
T5S1099 Liensinine Apoptosis , Mitophagy , Others , Autophagy
1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.
T5211 NSC 185058 NSC185058 Cysteine Protease , Autophagy
NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.
TN1140 Onjisaponin B AMPK , mTOR , Autophagy
Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parki...
T1554 Iohexol Mitophagy , Autophagy
Iohexol is a contrast agent. The osmolality of iohexol ranges from 322 mOsm/kg-approximately 1.1 times that of blood plasma-to 844 mOsm/kg, almost three times that of blood.
T2015 Fexaramine FXR , Autophagy
Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.
T15303 FMK 9a Cysteine Protease , Autophagy
FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.
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TargetMol