6-chloro-3-indolyl-b-d-glucuronide

6-Chloro-3-indolyl b-D-glucuronide sodium is a reagent used in biochemical reactions.

Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. bovisbiofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron.2It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively).3Nocardamine also induces morphological changes in BM-N4 insect cells.4 1.Lopez, J.A.V., Nogawa, T., Futamura, Y., et al.Nocardamin glucuronide, a new member of the ferrioxamine siderophores isolated from the ascamycin-producing strain Streptomyces sp. 80H647J. Antibiot. (Tokyo)72(12)991-995(2019) 2.Ishida, S., Arai, M., Niikawa, H., et al.Inhibitory effect of cyclic trihydroxamate siderophore, desferrioxamine E, on the biofilm formation of Mycobacterium speciesBiol. Pharm. Bull.34(6)917-920(2011) 3.Kalinovskaya, N.I., Romaneko, L.A., Irisawa, T., et al.Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activityMicrobiol. Res.166(8)654-661(2011) 4.Matsubara, K., Sakuda, S., Tanaka, M., et al.Morphological changes in insect BM-N4 cells induced by nocardamineBiosci. Biotechnol. Biochem.62(10)2049-2051(1998)

Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1 EDG-1, S1P2 EDG-5, S1P3 EDG-3, S1P4 EDG-6, and S1P5 EDG-8. W140 is an inactive enantiomer of W146, a selective S1P1 antagonist (Ki = 77 nM), that binds to the S1P1 receptor with a Ki of 4.6 μM (2a = W146; 2b = W140 in supplemental material). It exhibits no biological activity in vivo and can therefore serve as an effective control compound for experiments involving W146.

(2S,3R,4S,5R,6R)-3,4,5-Tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-ol is a useful organic compound for research related to life sciences. The catalog number is T67292 and the CAS number is 6564-72-3.

Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate known for activating the adenosine 5'-triphosphate-sensitive K+ channel, serving as a potential iron mobilizer by inhibiting the hepcidin-ferroportin interaction, and modulating the interleukin-6 (IL-6) stat-3 pathway. It is utilized in research on inflammation-related conditions, including anemia of inflammation (AI).

Methyl (3α,5α)-3-(acetyloxy)-6-oxocholan-24-oate is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

2',3'-O-Isopropylidene-6-mercaptopurine riboside is a compound with excellent metal complexation activity. It is utilized in the study of mechanisms involving metal complexation.

6-Chloro-3-indolyl α-D-galactopyranoside has potential applications in glycobiology research.

5-Bromo-6-chloro-3-indolyl-β-D-glucopyranoside has potential applications in glycobiology research.

5-Bromo-6-chloro-3-indolyl-N-acetyl-β-D-glucosaminide, 98%, is a chromogenic substrate utilized to assess β-galactosidase activity in foods, enzyme substrates, and culture media.

6-Chloro-1H-indol-3-yl β-D-glucopyranoside can be used as a chromogenic medium for detecting yeast with β-glucosidase activity.

5-Bromo-6-chloro-3-indolyl a-D-glucopyranoside is a biochemical reagent used in glycobiology research. Glycobiology focuses on the study of the structure, synthesis, biology, and evolution of sugars, encompassing carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan interactions, and the roles of glycans in biological systems. This field is closely linked to fundamental research, biomedicine, and biotechnology.

5-Bromo-6-chloro-1H-indol-3-yl α-D-galactopyranoside has potential applications in glycobiology research.

6-Chloro-3-indolyl 2-acetamido-2-deoxy-b-D-glucopyranoside has potential applications in glycobiology research.

4′-O-(β-D-2″,3″,4″,6″-Tetraacetyl-glucopyranosyl)-4-nitrophloretin is a biochemical reagent employed in glycoscience research. The study of glycoscience involves the examination of carbohydrate structures, synthesis, biological roles, and evolution. This field encompasses carbohydrate chemistry, the enzymology of glycan formation and degradation, protein-glycan interactions, and the functions of glycans in biological systems. It is intricately linked with fundamental research, biomedicine, and biotechnology.

Benzyl 2-acetamido-2-deoxy-3-O-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-α-D-galactopyranoside is a biochemical reagent used in glycoscience research, which examines the structure, synthesis, biology, and evolution of sugars. This field includes carbohydrate chemistry, the enzymology of glycan assembly and degradation, protein-glycan interactions, and the roles glycans play in biological systems. It is closely connected to fundamental research, biomedicine, and biotechnology.

Methyl 6-deoxy-2-O-methyl-3-O-benzyl-α-D-galactopyranoside is a biochemical reagent used in glycoscience research. Glycoscience explores the structure, synthesis, biology, and evolution of carbohydrates. The field involves carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems, closely linking with fundamental research, biomedicine, and biotechnology.

3-Acetyl-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose is a biochemical reagent used in glycobiology research. Glycobiology focuses on the study of the structure, synthesis, biology, and evolution of sugars. This field encompasses carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems, and it has close connections with fundamental research, biomedicine, and biotechnology.

4-Nitrophenyl 2-O-(6-deoxy-α-L-galactopyranosyl)-α-D-galactopyranoside is a reagent used in biochemical reactions.

3,6,2',3',4',6'-Hexa-O-acetyl-D-lactal is a reagent used in biochemical reactions.

6-Fluoro-3-indolyl-β-D-galactopyranoside is a chromogenic enzyme substrate commonly used in microbiology to detect the expression of β-galactosidase in bacterial colonies.

6-Chloro-1H-indol-3-yl palmitate is a reagent used in biochemical reactions.

6-Chloro-3-indoxyl butyrate is a reagent used in biochemical reactions.

6-Chloro-3-indoxyl-β-D-cellobioside is a reagent used in biochemical reactions.