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Search Results for " metabolism "

Targets

475

Compounds

196

Natural Products

172

Recombinant Proteins

23

Libraries

Cat No. Product Name Synonyms Targets
T9372 D-Histidine Mitochondrial Metabolism
D-Histidine is an enantiomer of L-histidine. L-Histidine is an inhibitor of mitochondrial glutamine transport and also an essential amino acid for infants.
T15373 Gboxin ATPase , Mitochondrial Metabolism
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.
T9777 THP104c Mitochondrial Metabolism
THP104c is an inhibitor of mitochondrial fission.
T12408 Perhexiline maleate Others , Mitochondrial Metabolism
Perhexiline maleate is an orally active inhibitor of CPT1 and CPT2 that reduces fatty acid metabolism. The IC50 values of perhexiline maleate against rat heart and liver CPT 1 were 77 and 148 μM, respectively.
T15241 ER-000444793 Others , Mitochondrial Metabolism
ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8 μM).
T14497 BAM 15 OXPHOS , Mitochondrial Metabolism
BAM 15 is an uncoupler of mitochondrial protonophore.
T19428 Mito-TEMPO Reactive Oxygen Species , Mitochondrial Metabolism
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO scavenges superoxide and alkyl radicals and prevents mitochondrial oxidation, necrosis and apoptosis.
T10706 CCI-006 Mitochondrial Metabolism
CCI-006, a selective inhibitor and chemosensitizer for MLL-rearranged leukemia cells, disrupts mitochondrial respiration. This action leads to irreversible mitochondrial depolarization and triggers a pro-apoptotic unfold...
T9169 MPP+ iodide Mitochondrial Metabolism , Autophagy
MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) ex...
T1768 7ACC2 Mitochondrial Metabolism , Monocarboxylate transporter
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.
T8734 Choline Others
Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins
T4639 Azemiglitazone MSDC 0602 Mitochondrial Metabolism , mTOR
Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.
T9031 MCU-i4 Others , Mitochondrial Metabolism
MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.
T3713 BAY-876 transporter
BAY-876 is an orally active and selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM). BAY-876 exhibits >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 also inhibits glycolytic metabol...
T2498 Adjudin AF-2364 Chloride channel , Mitochondrial Metabolism
Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.
T16342 KL1333 NQO1 activator 1 NADPH , Mitochondrial Metabolism
KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 ...
T4039 BIBB 515 Others
BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of...
T6816 DASA-58 PKM
DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.
T8732 CTPI-2 Others , Mitochondrial Metabolism
CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 μM). CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 ha...
T7093 Rafoxanide CDK , Parasite
Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.
T8500 VLX600 OXPHOS , Mitochondrial Metabolism , Autophagy
VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent. It acts by reducing mitochondrial oxidative phosphorylation in tumor cells.
T6834 FCCP Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone,Trifluoromethoxy carbonylcyanide phenylhydrazone ATPase , Mitochondrial Metabolism
FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. FCCP is often used as an apoptosis inducer.
T2367 SKF-86002 SKF86002 p38 MAPK , TNF
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).
T7837 SR8278 Others
SR8278 is an REV-ERBα antagonist(EC50 = 0.47 µM), blocking activation of the receptor by the synthetic agonist GSK 4112
T40514 ESP 15228 2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid Others
2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid is a ketone compound, compound example II-9. 2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid can be used for the research of cardiovascular diseases, dysproteinemias, dys...
T7835 CM10 CM 10 Dehydrogenase
CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.
T8308 NL-1 Mitochondrial Metabolism , Autophagy
NL-1 is a mitoNEET inhibitor with antileukemic effect.
T8366 Mitochonic acid 5 MA-5 Mitochondrial Metabolism
Mitochonic acid 5 (MA-5) is a derivative of the plant hormone indole-3-acetic acid. Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage.It has been shown to improve survival of f...
T9232 Mitochondrial fusion promoter M1 Mitochondrial Metabolism
Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in reducing brain and cardiac damage in rats suffering from cardia...
T4441 UK-5099 UK 5099,PF-1005023,UK5099 Others , Mitochondrial Metabolism
UK-5099 (PF-1005023) is a specific and potent inhibitor of MPC carrier activity [1]. It potently inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria (IC50: 50 nM) [1].
T8676 FOY 251 Others , Serine/threonin kinase , SARS-CoV
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
T6157 Devimistat CPI-613,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid Apoptosis , Dehydrogenase , Mitochondrial Metabolism
Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism. It has potent...
T5827 BI-6C9 Apoptosis , Others , Mitochondrial Metabolism
BI-6C9 is an inhibitor of tBid (Kd = 20 µM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.
T12148 N-Desmethyltamoxifen hydrochloride Estrogen Receptor/ERR , Endogenous Metabolite , PKC
N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.
T0412 Idebenone CV-2619 Apoptosis , Antioxidant , Mitochondrial Metabolism
Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).
T9211 Mito-LND Mito-Loidamine OXPHOS , Reactive Oxygen Species , Mitochondrial Metabolism , Autophagy
Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.
T7629 Olesoxime NSC 21311,TRO 19622 Mitochondrial Metabolism
Olesoxime (TRO 19622) (TRO19622), A Mitochondrial-Targeted Neuroprotective Compound,is an experimental neuroprotective drug.
T5363 Tempo 2,2,6,6-Tetramethylpiperidinooxy Free radical scavengers , Reactive Oxygen Species , DNA/RNA Synthesis , Mitochondrial Metabolism
Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy.
T3124 Carbendazim Bavistin,Carbendazole,Mercarzole Antifungal
Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspec...
T8766 GOT1 inhibitor-1 GOT1 inhibitor 2c Others
GOT1 inhibitor-1 (GOT1 inhibitor 2c) is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.
T5337 IACS-010759 IACS-10759,IACS 10759,IACS10759 Apoptosis , Others , Mitochondrial Metabolism
IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.
T0849 Pyrimethamine Pirimecidan,RP 4753,Pirimetamin DHFR , Antifolate , Parasite
Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.
T24656 PQ-10 A844337,PQ 10,A-844337,A 844337 PDE
PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.
T0239 Lonidamine AF1890,DICA,Diclondazolic Acid Apoptosis , Hexokinase , Mitochondrial Metabolism
Lonidamine (Diclondazolic Acid) is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK).
T2607 MSDC 0160 CAY10415,Mitoglitazone,MSDC0160,MSDC-0160 Others , IGF-1R , Mitochondrial Metabolism
MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.
T10814 Cinacalcet metabolite M4 Rarechem AL BW 1078 Calcium Channel
Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor.
T7487 Speract Others , Mitochondrial Metabolism
Speract, a peptide from sea urchin eggs, regulates sperm motility and stimulates sperm mitochondrial metabolism.
T35343 MTI-31 MTI-31,LXI-15029 mTOR
MTI-31 (LXI-15029) is a potent, orally active and highly selective inhibitor of mTORC1 and mTORC2. MTI-31 is selective for mTOR (Kd: 0.20 nM) versus PIK3CA, PIK3CB and PIK3G with >5,000 fold selectivity in mTOR binding a...
T1640 Ciprofloxacin Ciproxan,Ciprobay,Bay o 9867,Bay-09867 Topoisomerase , Antibacterial , Antibiotic
Ciprofloxacin (Bay-09867), a synthetic broad spectrum fluoroquinolone antibiotic, inhibits bacterial DNA gyrase. It is more active against Gram-negative bacteria than Gram-positive bacteria.
T9235 GW604714X 2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]- Mitochondrial Metabolism
GW604714X (2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-) were found to be potent inhibitors of mitochondrial respiration supported by pyruvate

Compounds

D-Histidine
T9372
Synonym:
Target: Mitochondrial Metabolism
Gboxin
T15373
Synonym:
Target: ATPase, Mitochondrial Metabolism
THP104c
T9777
Synonym:
Target: Mitochondrial Metabolism
Perhexiline maleate
T12408
Synonym:
Target: Others, Mitochondrial Metabolism
ER-000444793
T15241
Synonym:
Target: Others, Mitochondrial Metabolism
BAM 15
T14497
Synonym:
Target: OXPHOS, Mitochondrial Metabolism
Mito-TEMPO
T19428
Synonym:
Target: Reactive Oxygen Species, Mitochondrial Metabolism
CCI-006
T10706
Synonym:
Target: Mitochondrial Metabolism
MPP+ iodide
T9169
Synonym:
Target: Mitochondrial Metabolism, Autophagy
7ACC2
T1768
Synonym:
Target: Mitochondrial Metabolism, Monocarboxylate transporter
Choline
T8734
Synonym:
Target: Others
Azemiglitazone
T4639
Synonym: MSDC 0602
Target: Mitochondrial Metabolism, mTOR
MCU-i4
T9031
Synonym:
Target: Others, Mitochondrial Metabolism
BAY-876
T3713
Synonym:
Target: transporter
Adjudin
T2498
Synonym: AF-2364
Target: Chloride channel, Mitochondrial Metabolism
KL1333
T16342
Synonym: NQO1 activator 1
Target: NADPH, Mitochondrial Metabolism
BIBB 515
T4039
Synonym:
Target: Others
DASA-58
T6816
Synonym:
Target: PKM
CTPI-2
T8732
Synonym:
Target: Others, Mitochondrial Metabolism
Rafoxanide
T7093
Synonym:
Target: CDK, Parasite
VLX600
T8500
Synonym:
Target: OXPHOS, Mitochondrial Metabolism, Autophagy
FCCP
T6834
Synonym: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone,Trifluoromethoxy carbonylcyanide phenylhydrazone
Target: ATPase, Mitochondrial Metabolism
SKF-86002
T2367
Synonym: SKF86002
Target: p38 MAPK, TNF
SR8278
T7837
Synonym:
Target: Others
ESP 15228
T40514
Synonym: 2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid
Target: Others
CM10
T7835
Synonym: CM 10
Target: Dehydrogenase
NL-1
T8308
Synonym:
Target: Mitochondrial Metabolism, Autophagy
Mitochonic acid 5
T8366
Synonym: MA-5
Target: Mitochondrial Metabolism
Mitochondrial fusion promoter M1
T9232
Synonym:
Target: Mitochondrial Metabolism
UK-5099
T4441
Synonym: UK 5099,PF-1005023,UK5099
Target: Others, Mitochondrial Metabolism
FOY 251
T8676
Synonym:
Target: Others, Serine/threonin kinase, SARS-CoV
Devimistat
T6157
Synonym: CPI-613,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid
Target: Apoptosis, Dehydrogenase, Mitochondrial Metabolism
BI-6C9
T5827
Synonym:
Target: Apoptosis, Others, Mitochondrial Metabolism
N-Desmethyltamoxifen hydrochloride
T12148
Synonym:
Target: Estrogen Receptor/ERR, Endogenous Metabolite, PKC
Idebenone
T0412
Synonym: CV-2619
Target: Apoptosis, Antioxidant, Mitochondrial Metabolism
Mito-LND
T9211
Synonym: Mito-Loidamine
Target: OXPHOS, Reactive Oxygen Species, Mitochondrial Metabolism, Autophagy
Olesoxime
T7629
Synonym: NSC 21311,TRO 19622
Target: Mitochondrial Metabolism
Tempo
T5363
Synonym: 2,2,6,6-Tetramethylpiperidinooxy
Target: Free radical scavengers, Reactive Oxygen Species, DNA/RNA Synthesis, Mitochondrial Metabolism
Carbendazim
T3124
Synonym: Bavistin,Carbendazole,Mercarzole
Target: Antifungal
GOT1 inhibitor-1
T8766
Synonym: GOT1 inhibitor 2c
Target: Others
IACS-010759
T5337
Synonym: IACS-10759,IACS 10759,IACS10759
Target: Apoptosis, Others, Mitochondrial Metabolism
Pyrimethamine
T0849
Synonym: Pirimecidan,RP 4753,Pirimetamin
Target: DHFR, Antifolate, Parasite
PQ-10
T24656
Synonym: A844337,PQ 10,A-844337,A 844337
Target: PDE
Lonidamine
T0239
Synonym: AF1890,DICA,Diclondazolic Acid
Target: Apoptosis, Hexokinase, Mitochondrial Metabolism
MSDC 0160
T2607
Synonym: CAY10415,Mitoglitazone,MSDC0160,MSDC-0160
Target: Others, IGF-1R, Mitochondrial Metabolism
Cinacalcet metabolite M4
T10814
Synonym: Rarechem AL BW 1078
Target: Calcium Channel
Speract
T7487
Synonym:
Target: Others, Mitochondrial Metabolism
MTI-31
T35343
Synonym: MTI-31,LXI-15029
Target: mTOR
Ciprofloxacin
T1640
Synonym: Ciproxan,Ciprobay,Bay o 9867,Bay-09867
Target: Topoisomerase, Antibacterial, Antibiotic
GW604714X
T9235
Synonym: 2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-
Target: Mitochondrial Metabolism
1 2 3 4 5 6 7 8 9 10
Cat No. Product Name Synonyms Targets
TN1586 Dihydrorotenone Apoptosis , Mitochondrial Metabolism
Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.
T10857 Coenzyme A Endogenous Metabolite
Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.
T8433 HQNO Mitochondrial Metabolism
HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mitochondrial NDH-2 inhibitorin many species.
TN6772 Malabaricone C Others
Malabaricone C is a bioactive chemical.
T14140 Agaric acid Agaricinic Acid Mitochondrial Metabolism , AChR
Agaricic acid is an adenine nucleotide translocase antagonist.It is obtained from various plants of the fungous tribe, i.e. Polyporus officinalis and Polyporus igniarius. Agaric acid (Agaricinic Acid) induces mitochondri...
T8091 Trans-4-Hydroxycyclohexanecarboxylic Acid Others
trans-4-Hydroxycyclohexanecarboxylic Acid is an organic intermediate.
T7922 Kresoxim-Methyl Others , Mitochondrial Metabolism , Antifungal
Kresoxim-methyl is a strobilurin fungicide,inhibits conidial germination of V. inaequalis isolates from apple orchards .
T3804 Neomangiferin Mangiferin 7-glucoside Phosphatase
Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a biochemical mar...
T0938 Thiabendazole 2-(4-Thiazolyl)benzimidazole Microtubule Associated , Mitochondrial Metabolism , Parasite
Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.
T13795 Nicotinamide riboside Sirtuin
Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.
T4766 3-Methylglutaric acid Endogenous Metabolite
Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PMID 6181239 ). Methylglutaric acid is als...
T2970 Rotenone Rotenon,Paraderil,Barbasco,Rotocide,Dactinol Apoptosis , Dehydrogenase , Mitochondrial Metabolism , p53 , Autophagy
Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces...
TN1362 Afzelin Kaempferol-3-O-rhamnoside PTEN , p38 MAPK , TNF , Mitochondrial Metabolism , Antibacterial , Prostaglandin Receptor , Autophagy
Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protect human skin from UVB-induced d...
T0846 L-Carnitine L(-)-Carnitine,Levocarnitine Endogenous Metabolite , Fatty Acid Synthase
L-Carnitine (L(-)-Carnitine) is an amino acid derivative. L-Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering substrate for oxidation and subsequent energy production. Fatty acids are utiliz...
T5645 Nerol Cis-Geraniol,Neryl alcohol Apoptosis , Reactive Oxygen Species , Mitochondrial Metabolism , Endogenous Metabolite , Antifungal
Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian heart.
T2899 Liquiritin Liquiritigenin-4'-O-glucoside,Liquiritoside Reactive Oxygen Species
Liquiritin (Liquiritigenin-4'-O-glucoside) (LIQ) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.
T20089 ATP Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate Endogenous Metabolite
ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis. ATP can act as an extracellular signaling molecule through interactions with specifi...
T3898 Schaftoside APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE,Shaftoside Dynamin , Antioxidant , TLR , MyD88 , Mitochondrial Metabolism , Autophagy
Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.
T0437 Inosine INO 495,NSC 20262 ROS , Endogenous Metabolite , Adenosine Receptor
Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesic properties.
T6220 Nicotinamide riboside chloride Sirtuin , Endogenous Metabolite
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.
T9352 Hydrocotarnine Others
hydrocotarnine is an inhibitor of Cbl.
T2A2532 L-Histidine Glyoxaline-5-alanine,L-(-)-Histidine,histidine,L-Hisidine Mitochondrial Metabolism , Endogenous Metabolite
L-Histidine (L-(-)-Histidine) is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, L-Histidine is important for maintenance of myelin sheaths that protect ne...
T2901 Daidzin NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside Dehydrogenase , Reverse Transcriptase , Mitochondrial Metabolism
Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
TN1353 N-Benzyllinoleamide (9Z,12Z)-N-Benzyloctadeca-9,12-dienamide Others
N-Benzyllinoleamide ((9Z,12Z)-N-Benzyloctadeca-9,12-dienamide) is a natural product isolated from Lepidium meyenii Walp, has pharmaceutical property against exercise-induced fatigue.
T0700 Ursodeoxycholic acid UDCA,Ursodiol Potassium Channel , Endogenous Metabolite
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.
T1153 Trimethoprim NIH 204,BW 56-72,NSC-106568 DHFR , DNA/RNA Synthesis , Antifolate , Antibacterial , Antibiotic
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Tra...
T2812 ATP disodium salt hydrate ATP disodium,ATP disodium salt,Adenosine disodium triphosphate Others , Endogenous Metabolite
ATP disodium salt hydrate (Adenosine disodium triphosphate) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.
T9368 3,4-(Methylenedioxy)cinnamic acid 3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid Others
3,4-(Methylenedioxy)cinnamic acid (3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid) is a plant-derived compound first extracted from roots of Asparagus officinalis and further characterized as an allelochemical.
T5564 Tricarballylic acid β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,Carballylic acid,Propane-1,2,3-tricarboxylic acid aconitase , Mitochondrial Metabolism
Tricarballylic acid (Carballylic acid) is an inhibitor of aconitase.
T22235 Lipoic acid R-(+)-Thioctic acid,(R)-(+)-1,2-Dithiolane-3-pentanoic acid,(R)-(+)-α-Lipoic acid Reactive Oxygen Species , Mitochondrial Metabolism , Endogenous Metabolite
Lipoic acid (R-(+)-Thioctic acid) is an organosulfur compound derived from octanoic acid. It is made in animals normally, and is essential for aerobic metabolism.
T1352 ATP disodium salt Adenosine 5'-triphosphate disodium salt,ATP,ATP disodium,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate P2X Receptor , Endogenous Metabolite
ATP disodium salt (Adenosine-Triphosphate) is a P2 purinoceptor agonist.
T0200 α-Lipoic Acid Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid Apoptosis , NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite
α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme ...
T29078 Ursodeoxycholic acid sodium UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium FXR , Endogenous Metabolite , GPCR19
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it...
T5213 Acetyl phosphate(lithium potassium) Lithium potassium acetyl phosphate,Acetylphosphoric acid Others , Endogenous Metabolite
Acetyl phosphate lithium potassium (Lithium potassium acetyl phosphate) is a compound involved in taurine and hypotaurine metabolism as well as pyruvate metabolism. Acetyl phosphate lithium potassiu is generated from sul...
T4942 Galactose 1-phosphate Potassium salt α-D-Galactose-1-phosphate Dipotassium Pentahydrate Others , Endogenous Metabolite
Galactose 1-phosphate Potassium salt (α-D-Galactose-1-phosphate Dipotassium Pentahydrate) is an intermediate in the galactose metabolism and nucleotide sugars metabolism pathways.
TN6752 Dimethyl sulfone Endogenous Metabolite
Dimethyl sulfone exists in all living organisms, ranging from bacteria to humans. It derives from dietary sources, from intestinal bacterial metabolism and from human endogenous methanethiol metabolism. Dimethyl sulfone ...
T5078 Orotic acid monohydrate 2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate,Orotic Acid Monohydrate,2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate Others , Endogenous Metabolite
Orotic acid monohydrate is an intermediate product in pyrimidine metabolism.
T5251 Phenylpyruvic acid 2-Oxo-3-phenylpropanoic acid,3-Phenylpyruvic acid Others , Endogenous Metabolite
Phenylpyruvic acid (3-Phenylpyruvic acid) is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor. Levels of phenylpyruvate are normally very low in bloo...
T1040 Vitamin B12 Cyanocobalamin,Cobalamin Endogenous Metabolite
Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intes...
TN7132 4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone Others
4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone is a microbial metabolism of yangonin, a major styryl lactone from Piper methysticum.
T4829 3-Hydroxyphenylacetic acid Others , Endogenous Metabolite
3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxyphenylacetate 3-monooxygenase [EC 1.14.13.3] in the pathway tyro...
T10147 4-Hydroxymephenytoin (+/-)-4'-Hydroxymephenytoin Others , Drug Metabolite
4-Hydroxymephenytoin ((+/-)-4'-Hydroxymephenytoin) is the metabolism of an antiepileptic drug mephenytoin. Mephenytoin is used as a CYP2C19 substrate.
T10943 D-(-)-Lactic acid (R)-2-Hydroxypropionic acid Others , Endogenous Metabolite
D-(-)-Lactic acid is a normal intermediate in sugar fermentation (oxidation, metabolism). It is identified as a competitive inhibitor of ProDH (proline dehydrogenase) in plants.
T21367 Tetrahydrofolic acid 5,6,7,8-tetrahydrofolic acid,folate-H4,Tetrahydropteroylglutamic acid,th-folate Endogenous Metabolite
Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a vitamin B9 derivative that is a common one-carbon donor in organisms and is involved in growth and metabolism.
T14840 Butyrylcarnitine Endogenous Metabolite
Butyrylcarnitine is a plasma metabolite that is an indicator of abnormal metabolism due to disease and is used in the diagnosis of heart failure and pancreatic cysts.
T0894 Thiamine hydrochloride Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride Apoptosis , HBV , Endogenous Metabolite
Thiamine hydrochloride (Vitamin B1) is the hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, Thiami...
T19115 3,4-Dimethylbenzoic acid 1-Carboxy-3,4-dimethylbenzene Others
3,4-Dimethylbenzoic acid (1-Carboxy-3,4-dimethylbenzene) is a product of dimethylbenzoate metabolism by Rhodococcus rhodochrous N75.
T8714 1-Stearoyl-sn-glycero-3-phosphocholine 1-stearoyl-lysophosphatidylcholine,L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY Others
1-Stearoyl-sn-glycero-3-phosphocholine (L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY) is a chemical used in lipid metabolism studies
T0800 Danthron Dantron,1,8-Dihydroxyanthraquinone,Chrysazin,Antrapurol Virus Protease , Antibacterial , AMPK , Autophagy
Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.
T64980 ATP disodium trihydrate Adenosine-5'-triphosphate disodium trihydrate Endogenous Metabolite
ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) is an important substance for energy storage and metabolism in the body. It is an important endogenous signaling molecule in immunity and inflammati...
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Natural Products

Dihydrorotenone
TN1586
Synonym:
Target: Apoptosis, Mitochondrial Metabolism
Coenzyme A
T10857
Synonym:
Target: Endogenous Metabolite
HQNO
T8433
Synonym:
Target: Mitochondrial Metabolism
Malabaricone C
TN6772
Synonym:
Target: Others
Agaric acid
T14140
Synonym: Agaricinic Acid
Target: Mitochondrial Metabolism, AChR
trans-4-Hydroxycyclohexanecarboxylic Acid
T8091
Synonym:
Target: Others
Kresoxim-Methyl
T7922
Synonym:
Target: Others, Mitochondrial Metabolism, Antifungal
Neomangiferin
T3804
Synonym: Mangiferin 7-glucoside
Target: Phosphatase
Thiabendazole
T0938
Synonym: 2-(4-Thiazolyl)benzimidazole
Target: Microtubule Associated, Mitochondrial Metabolism, Parasite
Nicotinamide riboside
T13795
Synonym:
Target: Sirtuin
3-Methylglutaric acid
T4766
Synonym:
Target: Endogenous Metabolite
Rotenone
T2970
Synonym: Rotenon,Paraderil,Barbasco,Rotocide,Dactinol
Target: Apoptosis, Dehydrogenase, Mitochondrial Metabolism, p53, Autophagy
Afzelin
TN1362
Synonym: Kaempferol-3-O-rhamnoside
Target: PTEN, p38 MAPK, TNF, Mitochondrial Metabolism, Antibacterial, Prostaglandin Receptor, Autophagy
L-Carnitine
T0846
Synonym: L(-)-Carnitine,Levocarnitine
Target: Endogenous Metabolite, Fatty Acid Synthase
Nerol
T5645
Synonym: Cis-Geraniol,Neryl alcohol
Target: Apoptosis, Reactive Oxygen Species, Mitochondrial Metabolism, Endogenous Metabolite, Antifungal
Liquiritin
T2899
Synonym: Liquiritigenin-4'-O-glucoside,Liquiritoside
Target: Reactive Oxygen Species
ATP
T20089
Synonym: Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate
Target: Endogenous Metabolite
Schaftoside
T3898
Synonym: APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE,Shaftoside
Target: Dynamin, Antioxidant, TLR, MyD88, Mitochondrial Metabolism, Autophagy
Inosine
T0437
Synonym: INO 495,NSC 20262
Target: ROS, Endogenous Metabolite, Adenosine Receptor
Nicotinamide riboside chloride
T6220
Synonym:
Target: Sirtuin, Endogenous Metabolite
hydrocotarnine
T9352
Synonym:
Target: Others
L-Histidine
T2A2532
Synonym: Glyoxaline-5-alanine,L-(-)-Histidine,histidine,L-Hisidine
Target: Mitochondrial Metabolism, Endogenous Metabolite
Daidzin
T2901
Synonym: NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside
Target: Dehydrogenase, Reverse Transcriptase, Mitochondrial Metabolism
N-Benzyllinoleamide
TN1353
Synonym: (9Z,12Z)-N-Benzyloctadeca-9,12-dienamide
Target: Others
Ursodeoxycholic acid
T0700
Synonym: UDCA,Ursodiol
Target: Potassium Channel, Endogenous Metabolite
Trimethoprim
T1153
Synonym: NIH 204,BW 56-72,NSC-106568
Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic
ATP disodium salt hydrate
T2812
Synonym: ATP disodium,ATP disodium salt,Adenosine disodium triphosphate
Target: Others, Endogenous Metabolite
3,4-(Methylenedioxy)cinnamic acid
T9368
Synonym: 3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid
Target: Others
Tricarballylic acid
T5564
Synonym: β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,Carballylic acid,Propane-1,2,3-tricarboxylic acid
Target: aconitase, Mitochondrial Metabolism
Lipoic acid
T22235
Synonym: R-(+)-Thioctic acid,(R)-(+)-1,2-Dithiolane-3-pentanoic acid,(R)-(+)-α-Lipoic acid
Target: Reactive Oxygen Species, Mitochondrial Metabolism, Endogenous Metabolite
ATP disodium salt
T1352
Synonym: Adenosine 5'-triphosphate disodium salt,ATP,ATP disodium,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate
Target: P2X Receptor, Endogenous Metabolite
α-Lipoic Acid
T0200
Synonym: Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid
Target: Apoptosis, NF-κB, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite
Ursodeoxycholic acid sodium
T29078
Synonym: UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium
Target: FXR, Endogenous Metabolite, GPCR19
Acetyl phosphate(lithium potassium)
T5213
Synonym: Lithium potassium acetyl phosphate,Acetylphosphoric acid
Target: Others, Endogenous Metabolite
Galactose 1-phosphate Potassium salt
T4942
Synonym: α-D-Galactose-1-phosphate Dipotassium Pentahydrate
Target: Others, Endogenous Metabolite
Dimethyl sulfone
TN6752
Synonym:
Target: Endogenous Metabolite
Orotic acid monohydrate
T5078
Synonym: 2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate,Orotic Acid Monohydrate,2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate
Target: Others, Endogenous Metabolite
Phenylpyruvic acid
T5251
Synonym: 2-Oxo-3-phenylpropanoic acid,3-Phenylpyruvic acid
Target: Others, Endogenous Metabolite
Vitamin B12
T1040
Synonym: Cyanocobalamin,Cobalamin
Target: Endogenous Metabolite
4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone
TN7132
Synonym:
Target: Others
3-Hydroxyphenylacetic acid
T4829
Synonym:
Target: Others, Endogenous Metabolite
4-Hydroxymephenytoin
T10147
Synonym: (+/-)-4'-Hydroxymephenytoin
Target: Others, Drug Metabolite
D-(-)-Lactic acid
T10943
Synonym: (R)-2-Hydroxypropionic acid
Target: Others, Endogenous Metabolite
Tetrahydrofolic acid
T21367
Synonym: 5,6,7,8-tetrahydrofolic acid,folate-H4,Tetrahydropteroylglutamic acid,th-folate
Target: Endogenous Metabolite
Butyrylcarnitine
T14840
Synonym:
Target: Endogenous Metabolite
Thiamine hydrochloride
T0894
Synonym: Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride
Target: Apoptosis, HBV, Endogenous Metabolite
3,4-Dimethylbenzoic acid
T19115
Synonym: 1-Carboxy-3,4-dimethylbenzene
Target: Others
1-Stearoyl-sn-glycero-3-phosphocholine
T8714
Synonym: 1-stearoyl-lysophosphatidylcholine,L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY
Target: Others
Danthron
T0800
Synonym: Dantron,1,8-Dihydroxyanthraquinone,Chrysazin,Antrapurol
Target: Virus Protease, Antibacterial, AMPK, Autophagy
ATP disodium trihydrate
T64980
Synonym: Adenosine-5'-triphosphate disodium trihydrate
Target: Endogenous Metabolite

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00322 DEC-205 Protein, Human, Recombinant (His) Human HEK293 Cells
LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp...
TMPY-00395 Insulin Protein, Human, Recombinant Human P. pastoris (Yeast)
INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsul...
TMPY-02707 PAH Protein, Human, Recombinant (415 Asn/Asp, His) Human Baculovirus Insect Cells
PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding si...
TMPY-02062 SULT1A1 Protein, Human, Recombinant (His) Human E. coli
Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroid...
TMPY-04552 AKT1 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ...
TMPY-02219 Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) H1N1 E. coli
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N...
TMPY-00481 AKR1C4 Protein, Human, Recombinant (His) Human E. coli
Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation ...
TMPJ-01072 GALK2 Protein, Human, Recombinant (His) Human HEK293 Cells
GALK2 acts as a galactokinase when galactose is present at high concentrations. GALK2 may be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates. GALK2...
TMPH-01563 IAPP Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
TMPK-00516 BST1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
BST1 overexpression conferred resistance to sphingosine in yeast. BST1 deletion produced sensitivity to exogenous D-erythro-sphingosine and phytosphingosine and intracellular accumulation of sphingosine 1-phosphate upon ...
TMPH-01670 Metallothionein-4/MT4 Protein, Human, Recombinant (His & SUMO) Human E. coli
Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia.
TMPJ-00158 Apolipoprotein A-I/APOA1 Protein, Human, Recombinant Human E. coli
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various...
TMPH-00608 Dihydrofolate reductase Protein, E. coli, Recombinant (His) E. coli E. coli
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
TMPH-02561 CES1C Protein, Mouse, Recombinant (GST) Mouse E. coli
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant.
TMPH-02562 CES1C Protein, Mouse, Recombinant (His & Myc) Mouse HEK293 Cells
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant.
TMPY-02622 Aldolase B Protein, Human, Recombinant (GST) Human E. coli
The aldolase family members involved in metabolism and glycolysis are present in three isoforms: ALDOA, ALDOB, and ALDOC. Aldolases are differentially expressed in human tissues, and aberrant expression has been observed...
TMPJ-01296 SULT4A1 Protein, Human, Recombinant Human E. coli
Sulfotransferase 4A1 (ST4A1) is a member of the Sulfotransferase 1 family. ST4A1 is highly expressed in the cerebral cortex and frontal lobe, but no expression is detected in the pancreas. ST4A1 is a brain-specific sulfo...
TMPH-02618 CYP2E1 Protein, Mouse, Recombinant (His) Mouse E. coli
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electr...
TMPH-01360 GALT Protein, Human, Recombinant (His & SUMO) Human E. coli
Plays an important role in galactose metabolism. GALT Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 59.4 kDa and the accession...
TMPK-01087 Apolipoprotein A-V/APOA5 Protein, Mouse, Recombinant (His) Mouse E. coli
APOA5 is probably the gene with the strongest effect on triglyceride (TG) metabolism. APOA5 is almost exclusively expressed in the liver, and its product apoAV has a very low circulating concentration. New physiological ...
TMPH-03387 TSHB Protein, Rat, Recombinant (His & Myc) Rat P. pastoris (Yeast)
Indispensable for the control of thyroid structure and metabolism. TSHB Protein, Rat, Recombinant (His & Myc) is expressed in yeast with N-6xHis and C-Myc tag. The predicted molecular weight is 16.4 kDa and the accession...
TMPH-02526 Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synth...
TMPH-02685 GPHB5 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid ce...
TMPK-00101 IL-6 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 recep...
TMPH-00615 RecF Protein, E. coli, Recombinant (His & SUMO) E. coli E. coli
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.
TMPH-03386 TSHB Protein, Rat, Recombinant (E. coli, His & Myc) Rat E. coli
Indispensable for the control of thyroid structure and metabolism. TSHB Protein, Rat, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight...
TMPH-01562 IAPP Protein, Human, Recombinant (GST) Human E. coli
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP Protein, Human, Recombinant (GST) is expressed in E. coli expression s...
TMPY-04771 CARKL Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
CARKL, also known as SHPK, is a nonprotein kinase of glucose metabolism. CARKL has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibi...
TMPH-00198 Bet v 3 Protein, Betula pendula, Recombinant (His & Myc & SUMO) Betula pendula E. coli
Could be involved in calcium metabolism in pollen. Binds 3 calcium ions. Bet v 3 Protein, Betula pendula, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The pre...
TMPH-02563 CES1C Protein, Mouse, Recombinant Mouse E. coli
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant. CES1C Protein, Mouse, Recombinant is expressed in E. coli expr...
TMPH-01224 Dihydrofolate reductase Protein, Human, Recombinant (His) Human E. coli
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds...
TMPY-02288 Glyoxalase II/HAGH Protein, Human, Recombinant (His) Human E. coli
HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase an...
TMPH-03535 Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) Staphylococcus aureus E. coli
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) is expressed...
TMPH-03021 PstP Protein, Mycobacterium tuberculosis, Recombinant (His) Mycobacterium tuberculosis E. coli
Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth an...
TMPH-03293 FGF-23 Protein, Rat, Recombinant (E. coli, His) Rat E. coli
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Ac...
TMPK-00050 Leptin Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Leptin has key roles in the regulation of energy balance, body weight, metabolism, and endocrine function. Leptin levels are undetectable or very low in patients with lipodystrophy, hypothalamic amenorrhea, and congenita...
TMPH-03581 Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) Staphylococcus epidermidis E. coli
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) is expressed ...
TMPH-01859 PISD Protein, Human, Recombinant (His & SUMO) Human E. coli
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. PISD Protein, Hu...
TMPH-00911 GPT Protein, Human, Recombinant (His) Human E. coli
Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transport...
TMPH-02684 GPHB5 Protein, Mouse, Recombinant (His) Mouse P. pastoris (Yeast)
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid ce...
TMPH-01087 CSH2 Protein, Human, Recombinant (GST & His) Human E. coli
Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. CSH2 Protein, Human, Recombinant...
TMPH-01094 CELA2A Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
TMPH-02582 CELA2A Protein, Mouse, Recombinant (His) Mouse E. coli
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
TMPY-01217 ANGPTL5 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
The angiopoietins are protein growth factors that promote angiogenesis, the formation of blood vessels from pre-existing blood vessels. There are now four identified angiopoietins: Ang1, Ang2, Ang3, Ang4. In addition, th...
TMPY-05099 GBA/glucocerebrosidase Protein, Human, Recombinant (His) Human HEK293 Cells
Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramida...
TMPH-03503 Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO) Shigella flexneri E. coli
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase Protein, Shigella flexn...
TMPJ-01302 ACAT2 Protein, Human, Recombinant (His) Human E. coli
ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family. ACAT2 takes part in lipid metabolism, lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. It is responsible for the synthesi...
TMPH-01298 EPHX1 Protein, Human, Recombinant (His) Human E. coli
Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Plays a role in the metabolism of endogenous lip...
TMPJ-01248 Cytoglobin/CYGB Protein, Human, Recombinant (His) Human E. coli
Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be...
TMPH-01093 CELA2A Protein, Human, Recombinant (E. coli, His) Human E. coli
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
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DEC-205 Protein, Human, Recombinant (His)
TMPY-00322
Species: Human
Expression System: HEK293 Cells
Insulin Protein, Human, Recombinant
TMPY-00395
Species: Human
Expression System: P. pastoris (Yeast)
PAH Protein, Human, Recombinant (415 Asn/Asp, His)
TMPY-02707
Species: Human
Expression System: Baculovirus Insect Cells
SULT1A1 Protein, Human, Recombinant (His)
TMPY-02062
Species: Human
Expression System: E. coli
AKT1 Protein, Human, Recombinant (His)
TMPY-04552
Species: Human
Expression System: Baculovirus Insect Cells
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)
TMPY-02219
Species: H1N1
Expression System: E. coli
AKR1C4 Protein, Human, Recombinant (His)
TMPY-00481
Species: Human
Expression System: E. coli
GALK2 Protein, Human, Recombinant (His)
TMPJ-01072
Species: Human
Expression System: HEK293 Cells
IAPP Protein, Human, Recombinant (His)
TMPH-01563
Species: Human
Expression System: P. pastoris (Yeast)
BST1 Protein, Cynomolgus, Recombinant (His)
TMPK-00516
Species: Cynomolgus
Expression System: HEK293 Cells
Metallothionein-4/MT4 Protein, Human, Recombinant (His & SUMO)
TMPH-01670
Species: Human
Expression System: E. coli
Apolipoprotein A-I/APOA1 Protein, Human, Recombinant
TMPJ-00158
Species: Human
Expression System: E. coli
Dihydrofolate reductase Protein, E. coli, Recombinant (His)
TMPH-00608
Species: E. coli
Expression System: E. coli
CES1C Protein, Mouse, Recombinant (GST)
TMPH-02561
Species: Mouse
Expression System: E. coli
CES1C Protein, Mouse, Recombinant (His & Myc)
TMPH-02562
Species: Mouse
Expression System: HEK293 Cells
Aldolase B Protein, Human, Recombinant (GST)
TMPY-02622
Species: Human
Expression System: E. coli
SULT4A1 Protein, Human, Recombinant
TMPJ-01296
Species: Human
Expression System: E. coli
CYP2E1 Protein, Mouse, Recombinant (His)
TMPH-02618
Species: Mouse
Expression System: E. coli
GALT Protein, Human, Recombinant (His & SUMO)
TMPH-01360
Species: Human
Expression System: E. coli
Apolipoprotein A-V/APOA5 Protein, Mouse, Recombinant (His)
TMPK-01087
Species: Mouse
Expression System: E. coli
TSHB Protein, Rat, Recombinant (His & Myc)
TMPH-03387
Species: Rat
Expression System: P. pastoris (Yeast)
Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02526
Species: Mouse
Expression System: E. coli
GPHB5 Protein, Mouse, Recombinant (His & Myc)
TMPH-02685
Species: Mouse
Expression System: E. coli
IL-6 Protein, Cynomolgus, Recombinant (His)
TMPK-00101
Species: Cynomolgus
Expression System: HEK293 Cells
RecF Protein, E. coli, Recombinant (His & SUMO)
TMPH-00615
Species: E. coli
Expression System: E. coli
TSHB Protein, Rat, Recombinant (E. coli, His & Myc)
TMPH-03386
Species: Rat
Expression System: E. coli
IAPP Protein, Human, Recombinant (GST)
TMPH-01562
Species: Human
Expression System: E. coli
CARKL Protein, Human, Recombinant (His & GST)
TMPY-04771
Species: Human
Expression System: Baculovirus Insect Cells
Bet v 3 Protein, Betula pendula, Recombinant (His & Myc & SUMO)
TMPH-00198
Species: Betula pendula
Expression System: E. coli
CES1C Protein, Mouse, Recombinant
TMPH-02563
Species: Mouse
Expression System: E. coli
Dihydrofolate reductase Protein, Human, Recombinant (His)
TMPH-01224
Species: Human
Expression System: E. coli
Glyoxalase II/HAGH Protein, Human, Recombinant (His)
TMPY-02288
Species: Human
Expression System: E. coli
Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)
TMPH-03535
Species: Staphylococcus aureus
Expression System: E. coli
PstP Protein, Mycobacterium tuberculosis, Recombinant (His)
TMPH-03021
Species: Mycobacterium tuberculosis
Expression System: E. coli
FGF-23 Protein, Rat, Recombinant (E. coli, His)
TMPH-03293
Species: Rat
Expression System: E. coli
Leptin Protein, Mouse, Recombinant (hFc)
TMPK-00050
Species: Mouse
Expression System: HEK293 Cells
Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)
TMPH-03581
Species: Staphylococcus epidermidis
Expression System: E. coli
PISD Protein, Human, Recombinant (His & SUMO)
TMPH-01859
Species: Human
Expression System: E. coli
GPT Protein, Human, Recombinant (His)
TMPH-00911
Species: Human
Expression System: E. coli
GPHB5 Protein, Mouse, Recombinant (His)
TMPH-02684
Species: Mouse
Expression System: P. pastoris (Yeast)
CSH2 Protein, Human, Recombinant (GST & His)
TMPH-01087
Species: Human
Expression System: E. coli
CELA2A Protein, Human, Recombinant (His)
TMPH-01094
Species: Human
Expression System: P. pastoris (Yeast)
CELA2A Protein, Mouse, Recombinant (His)
TMPH-02582
Species: Mouse
Expression System: E. coli
ANGPTL5 Protein, Human, Recombinant (GST)
TMPY-01217
Species: Human
Expression System: Baculovirus Insect Cells
GBA/glucocerebrosidase Protein, Human, Recombinant (His)
TMPY-05099
Species: Human
Expression System: HEK293 Cells
Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO)
TMPH-03503
Species: Shigella flexneri
Expression System: E. coli
ACAT2 Protein, Human, Recombinant (His)
TMPJ-01302
Species: Human
Expression System: E. coli
EPHX1 Protein, Human, Recombinant (His)
TMPH-01298
Species: Human
Expression System: E. coli
Cytoglobin/CYGB Protein, Human, Recombinant (His)
TMPJ-01248
Species: Human
Expression System: E. coli
CELA2A Protein, Human, Recombinant (E. coli, His)
TMPH-01093
Species: Human
Expression System: E. coli
Cat No. Product Name
L2510 Lipid Metabolism Compound Library

492 compounds
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
L2550 Glutamine Metabolism Compound Library

565 compounds
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ...
L2130 Anti-Cancer Metabolism Compound Library

1268 compounds
A unique collection of 1268 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS);
L5200 Anti-Metabolism Disease Compound Library

1544 compounds
A unique collection of 1544 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
L2560 Metabolism Compound Library

2320 compounds
A unique collection of 2320 metabolic pathway-related bioactive small molecule compounds for high-throughput, high-content screening.
L2520 Glycometabolism Compound Library

702 compounds
702 glycometabolism-related comounds, can be used for HTS and HCT;
L2501 Human Endogenous Metabolite Compound Library Plus

1283 compounds
A unique collection of 1283 endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening.
L2100 Anti-Cancer Compound Library

7234 compounds
A unique collection of 7234 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L1510 Nuclear Receptor Compound Library

531 compounds
A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;
L2540 Gut Microbial Metabolite Library

614 compounds
A unique collection of 614 gut microbial metabolites which can be used for HTS and HCS;
L2400 Endocrinology-Hormone Compound Library

784 compounds
A unique collection of 784 compounds targeting endocrine system for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L2160 Anti-Cancer Active Compound Library

3188 compounds
A unique collection of 3188 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L6130 Terpene Natural Product Library

516 compounds
A unique collection of 516 natural terpenes and terpenoids can be used for high throughput and high content screening;
L1610 FDA-Approved Kinase Inhibitor Library

263 compounds
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L2150 Anti-Cancer Drug Library

3080 compounds
A unique collection of 3080 anticancer drugs for high throughput screening (HTS) and high content screening (HCS);
L2120 Anti-Cancer Clinical Compound Library

2545 compounds
A unique collection of 2545 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
L1120 AMPK-Targeted Compound Library

80 compounds
80 well-chosen unique AMPK-targeted small molecules;
L2110 Anti-Cancer Approved Drug Library

1779 compounds
A unique collection of 1779 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS);
L2180 Anti-Cancer Compound Library Plus

1468 compounds
Well-chosen 1468 anti-tumor compounds with unique structures;
L5300 Mitochondria-Targeted Compound Library

812 compounds
A unique collection of 812 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;
L6120 Flavonoid Natural Product Library

514 compounds
A unique collection of 514 flavonoids can be used for high throughput and high content screening;
L7100 Anti-Obesity Compound Library

2247 compounds
A unique collection of 2247 anti-obesity compounds for high throughput and high content screening;
L8500 HIF-1 Signaling Pathway Compound Library

1336 compounds
A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;
TargetMol