s-3

LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM.

Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist that binds to DREADD receptor subtypes [hM3Dq] and [hM4Di] with Ki values of 6.3 nM and 4.2 nM, respectively.

F8-S43-S3 is a SARS-CoV-2 main protease inhibitor (IC 50 = 9.69 μM) [1].

S3 Fragment is a biologically active peptide featuring the amino-terminal phosphorylation site unique to Xenopus ADF/cofilin, which is the target of LIM kinase (LIMK) phosphorylation. LIMK1, a pivotal regulator of the actin cytoskeleton, phosphorylates ADF/cofilin at serine-3, leading to its inactivation. As a segment of the S3 peptide harboring the serine-3 sequence, this fragment serves as a widely recognized competitive inhibitor of LIMK1.

Dermaseptin-S3 is an antimicrobial peptide derived from frog skin, exhibiting activity against filamentous fungi [1].

AS-35 is an orally effective, potent, and selective antagonist of leukotrienes, antagonizing LTC4-, LTD4-, and LTE4-induced ileum contractions with IC50 values of 8 nM, 4 nM, and 3 nM, respectively. It exhibits antiallergic activities.

BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of <1.7 nM.

BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.

BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.

Cis-3-Hexenyl Formate is an ester compound widely used in biochemical experiments and drug synthesis research.

cis-3-Hexenyl benzoate is a mild and long-lasting herbal fragrance component primarily used in chypre and woody perfumes.

cis-3-Hexen-1-ol ((Z)-3-Hexen-1-ol) is an aroma compound described as green grassy or the smell of cut grass. It is found in many fresh fruits and vegetables and is widely used as a flavor additive in processed food and perfumes. cis-3-Hexen-1-ol also attracts various insects[1][2].

trans-3-Indoleacrylic acid is one of the endogenous metabolites that inhibits RSL3-induced ferroptosis and can be used to study colorectal cancer.

TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) is an agonist of TRPM8( EC50 : 3.7 μM).

Cis-3-Hexenyl Butyrate ((Z)-3-hexen-1-yl butyrate) is an attractant for oviposition of grapholitha molesta.

cis-3-Hexenyl acetate is an unsaturated ester compound widely used in biochemical experiments and drug synthesis research.

cis-3-Hexenyl hexanoate is an active compound. cis-3-Hexenyl hexanoate ester can be isolated from yellow-flowered delphinium and is also present in some fruits, where it has a strong fruity flavor.

OS-3-106 is a novel arylamide phenylpiperazines, as partial agonists at the D3R in the adenylyl cyclase inhibition assay.

FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for MAT2A binding.

(VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH), also known as (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, is a conjugate compound comprising a ligand-linker that targets E3 ligase and features a VHL ligand on one end. It is employed in PROTAC technology applications.

(Z)-S-3-dodecenoate-CoA ((Z)-S-3-dodecenoate-Coenzyme A) is a derivative of coenzyme A.

Compound PS - 3771 is mainly used as an intermediate for dyes, an intermediate for pharmaceuticals, and a sensitizer for color motion picture films.

Glucagon receptor antagonist -3 is a highly effective glucagon receptor antagonist.

MRS-3777 hemioxalate, a selective adenosine A3 receptor antagonist, reverses the anti-injury perception effects of its corresponding agonist and serves as a valuable tool for studying inflammatory pain.