s-3

LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM.

Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist that binds to DREADD receptor subtypes [hM3Dq] and [hM4Di] with Ki values of 6.3 nM and 4.2 nM, respectively.

F8-S43-S3 is a highly effective entry inhibitor targeting enveloped viruses. It exhibits significant in vitro neutralizing activity against various influenza strains by binding to specific viral surface glycoproteins and interfering with the membrane fusion process.

S3 Fragment is a biologically active peptide featuring the amino-terminal phosphorylation site unique to Xenopus ADF/cofilin, which is the target of LIM kinase (LIMK) phosphorylation. LIMK1, a pivotal regulator of the actin cytoskeleton, phosphorylates ADF/cofilin at serine-3, leading to its inactivation. As a segment of the S3 peptide harboring the serine-3 sequence, this fragment serves as a widely recognized competitive inhibitor of LIMK1.

Dermaseptin-S3 is an antimicrobial peptide derived from frog skin, exhibiting activity against filamentous fungi [1].

AS-35 is an orally effective, potent, and selective antagonist of leukotrienes, antagonizing LTC4-, LTD4-, and LTE4-induced ileum contractions with IC50 values of 8 nM, 4 nM, and 3 nM, respectively. It exhibits antiallergic activities.

BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of <1.7 nM.

BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.

BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.

Tert-butyl cis-3-hydroxymethylcyclobutylcarbamate ,with CAS No. 142733-64-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Tert-butyl cis-3-hydroxymethylcyclobutylcarbamate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Cis-3-Hexenyl Formate is an ester compound widely used in biochemical experiments and drug synthesis research.

cis-3-Hexenyl benzoate is a mild and long-lasting herbal fragrance component primarily used in chypre and woody perfumes.

cis-3-Hexen-1-ol ((Z)-3-Hexen-1-ol) is an aroma compound described as green grassy or the smell of cut grass. It is found in many fresh fruits and vegetables and is widely used as a flavor additive in processed food and perfumes. cis-3-Hexen-1-ol also attracts various insects[1][2].

trans-3-Indoleacrylic acid is one of the endogenous metabolites that inhibits RSL3-induced ferroptosis and can be used to study colorectal cancer.

TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) is an agonist of TRPM8( EC50 : 3.7 μM).

Cis-3-Hexenyl Butyrate ((Z)-3-hexen-1-yl butyrate) is an attractant for oviposition of grapholitha molesta.

cis-3-Hexenyl acetate is an unsaturated ester compound widely used in biochemical experiments and drug synthesis research.

cis-3-Hexenyl hexanoate is an active compound. cis-3-Hexenyl hexanoate ester can be isolated from yellow-flowered delphinium and is also present in some fruits, where it has a strong fruity flavor.

OS-3-106 is a novel arylamide phenylpiperazines, as partial agonists at the D3R in the adenylyl cyclase inhibition assay.

FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for MAT2A binding.

(VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH), also known as (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, is a conjugate compound comprising a ligand-linker that targets E3 ligase and features a VHL ligand on one end. It is employed in PROTAC technology applications.

(Z)-S-3-dodecenoate-CoA ((Z)-S-3-dodecenoate-Coenzyme A) is a derivative of coenzyme A.

Glucagon receptor antagonist -3 is a highly effective glucagon receptor antagonist.

MRS-3777 hemioxalate, a selective adenosine A3 receptor antagonist, reverses the anti-injury perception effects of its corresponding agonist and serves as a valuable tool for studying inflammatory pain.