analog

NSC 601980 analog, an analog of NSC601980, demonstrates antitumor activity in yeast screening experiments.

DO34 analog is a triazole-based inhibitor of DAGL(α).

RR-11a analog (aza-peptide Michael acceptor, 7a) is an inhibitor of asparaginyl endopeptidase with IC50s of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively.

AR-13324 analog mesylate, an inhibitor of Rho-kinase and the norepinephrine transporter, reduces intraocular pressure in normotensive monkey eyes.

Ecteinascidins are a family of tetrahydroisoquinoline alkaloids known for their antitumor and antimicrobial activities. [Ecteinascidin-Analog-1] is a valuable intermediate for the synthesis of Ecteinascidin analogues.

OT antagonist 3 analog is an analogue of OT antagonist 3.

Resveratrol analog 2 is an analog of Resveratrol, a natural polyphenolic phytoalexin with anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties.

WEHI-345 analog is an Src inhibitor.

LY88074 analog 1, a benzothiophene compound with nitrogen-containing non-basic side chains, can be utilized either independently or alongside estrogen or progestin. This agent is effective for mitigating post-menopausal symptoms, including osteoporosis, cardiovascular-related pathological conditions, and estrogen-dependent cancer.

DB04760 analog 1 is an analogue of DB04760.

Duocarmycin Analog is used as an DNA alkylator and ADC cytotoxin. Duocarmycin Analog is an analog of Duocarmycin.

Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication.

Nucleoside-Analog-2 is a 4'-Azidocytidine analogue used against Hepatitis C virus (HCV) replication.

Pimelic Diphenylamide 106 analog is an Pimelic Diphenylamide 106 analog .

Thiamine diphosphate analog 1, an analog of Thiamine diphosphate (the active form of vitamin B1 and a universal cofactor in key cellular pathways), mirrors the structure and potentially the function of its prototype.

MK-8245 analog is an analog of MK-8245 which is a liver-targeted Inhibitor of Stearoyl-CoA Desaturase (SCD). It is useful for the Treatment of Dyslipidemia and Diabetes.

α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 µg per animal dose, indicating a Th2 response.

Desmethyl-WEHI-345 analog, a protein kinase inhibitor, holds potential for colon cancer research.

Hoechst 33342 analog trihydrochloride, an analog of Hoechst 33342, serves as a fluorochrome by binding to the minor groove of DNA, facilitating the visualization of cellular DNA.

CE3F4 analog 1 is an analogue of CE3F4. It is a chemical compound utilized in various [scientific applications] due to its unique properties, notably in (radical scavenging) and (oxidation-reduction) processes. It plays a significant role in advanced (catalysis), (pharmaceutical) research, and (material science) due to its stability and reactivity.

MRTX849 analog 24, an alkyne-containing click probe analogue of the MRTX849 inhibitor for KRAS G12C, is designed for studying MRTX849 functionality.

PP2 Analog is an analog of PP2. It also acts as a protein trafficking modulator.

MGCD-265 analog (Glesatinib) is an orally bioavailable multitargeted tyrosine kinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively.

Laropiprant analog is an antagonist of the prostaglandin PGD2 receptor DP1.