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  • Inhibitors & Agonists
    641
    TargetMol | Inhibitors_Agonists
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Tabernanthalog
TBG
T602212483829-58-7
Tabernanthalog (TBG) is a 5-HT2A agonist. In rodents,Tabernanthalog has been found to promote structural neuroplasticity, reduce alcohol-seeking and heroin-seeking behavior, and produce antidepressant effects.
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Astragaloside IV
AST-IV, AS-IV
T297384687-43-4
Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1 2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.1 It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 μM; LC50 = 865 μM).It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. In particular, it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts.
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Zalospirone
T68172114298-18-9In house
Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.
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Galocitabine
RO-09-1390, RO-091390, RO091390, RO 091390, Neofrutulon
T27399124012-42-6In house
Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.
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6-8 weeks
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Lasalocid A ammonium
Lasalocid A ammonium(25999-31-9 Free base)
T15717L33855-11-7In house
Lasalocid A ammonium is an amine-selective ion carrier and feed additive with antimicrobial activity and antibiotic, growth-promoting properties, inhibits the protozoa of falciparum malaria, and can be used in the study of microbial infections.
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RR-11a analog
aza-peptide Michael acceptor, 7a
T12770685543-66-2In house
RR-11a analog (aza-peptide Michael acceptor, 7a) is an inhibitor of asparaginyl endopeptidase with IC50s of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively.
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6-8 weeks
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Halopemide
T1546159831-65-1In house
Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2). Halopemid is an antagonist of dopamine receptors. Halopemid can be used in psychotropic research.
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6-8 weeks
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Ticalopride
T69984202590-69-0In house
Ticalopride is a 5-HT3 receptor agonist used in the treatment of digestive disorders, orofacial disorders, otorhinolaryngologic disorders, and may be used in the study of bulimia nervosa, gastroesophageal reflux, and irritable bowel syndrome.
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6-8 weeks
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ALOX15-IN-2
T626062764818-23-5In house
ALOX15-IN-2 is a potent inhibitor of ALOX15 linoleate oxygenase activity, inhibiting the oxidation of linoleic acid (LA) and arachidonic acid (AA), the immediate homologs of ALOX15, with IC50s of 1.55 and 2.79 μM, respectively.
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10-14 weeks
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Brefonalol HCl
Brefonalol HCl(103880-26-8 Free base)
T30586L In house
Brefonalol HCl is an ADRA antagonist used in the treatment of neurological disorders and cardiovascular diseases and can be used in the study of angina pectoris, arrhythmias and hypertension.
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DO34 analog
T110702098969-71-0In house
DO34 analog is a triazole-based inhibitor of DAGL(α).
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6-8 weeks
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Talotrexin ammonium
T64295648420-92-2In house
Talotrexin ammonium is a non-polyglutamic acid antifolate. Talotrexin ammonium inhibits tumor growth by targeting dihydrofolate reductase (DHFR), thereby improving anti-tumor activity in a wide range of cancer models, helping to inhibit tumor growth.
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6-8weeks
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Aloisine B
AloisineB
T69188496864-14-3In house
Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively. Aloisine B has antiviral activity and can be used to study Alzheimer's, diabetes, HIV and Parkinson's.
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6-8 weeks
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Filgotinib analogue
GLPG0634 analogue, GLPG 0634 analogue
T200418 In house
Filgotinib analogue isa a structurally analogue of Filgotinib and can be used in life science related research.
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TargetMol
Valomaciclovir stearate
RP-606, RP606, A-174606.0, MIV-606, EPB-348, ABT-606
T29093195156-77-5In house
Valomaciclovir stearate (A-174606. 0) is a nucleoside analog with antiviral activity against varicella-zoster virus (VZV), and has been used in the study of VZV infections.
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8-10 weeks
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Clozapine Analogues
T84365124380-97-8In house
Clozapine Analogues can be used to study neurological disorders.
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Edasalonexent
CAT-1004
T151981204317-86-1In house
Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor designed to improve Duchenne muscular dystrophy.
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6-8 weeks
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Phenothiazine Analogues
T85313423749-25-1In house
3-Amino-1-(2-chloro-10H-phenothiazin-10-yl)-1-propanone is involved in the synthesis of phenothiazine series compounds.
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Geranyl linalool
T842201113-21-9
Geranyl linalool is a fragrance ingredient extracted from Brunfelsia uniflora with potential insecticide, antibacterial, antioxidant and anticancer activities.
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Cephalonium
Cefalonium
T01415575-21-3
Cephalonium (Cefalonium) is a first-generation cephalosporin antibiotic.
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Dimethyl malonate
T5695108-59-8
Dimethyl Malonate is a Succinate Dehydrogenase inhibitor.
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7-Methoxy-1-tetralone
Fr122756836-19-7
7-Methoxy-1-tetralone may have insecticidal activity.
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Aloe emodin
Rhabarberone, NSC 38628, Aloe-emodin, 3-Hydroxymethylchrysazine
T2843481-72-1
Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV (IC50=1 μg mL) and EV71(IC50=0.33 μg mL ).
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Dimethylmalonic acid
2,2-Dimethylmalonic acid
T19284595-46-0
Dimethylmalonic acid(2,2-Dimethylmalonic acid) is a short-chain dicarboxylic acid found in human serum that can be used to prevent or retard denaturation of fish actinomyosin in freezing buffer solution (pH 7).
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7-10 days
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