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Poly(styrenyl acetal trehalose)
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Catalog No. TCL-01236
Alias pSAT
Poly(styrenyl acetal trehalose) (pSAT) is synthesized by linking trehalose side chains to a polystyrene backbone through acetal bonds. This compound stabilizes various proteins and enzymes against temperature fluctuations without triggering an innate immune response. Additionally, Poly(styrenyl acetal trehalose) can be utilized in synthesizing protein-polymer conjugates, thereby reducing the renal clearance of active molecules.
Poly(styrenyl acetal trehalose)
Poly(styrenyl acetal trehalose)
😃Good
Catalog No. TCL-01236Alias pSAT
Poly(styrenyl acetal trehalose) (pSAT) is synthesized by linking trehalose side chains to a polystyrene backbone through acetal bonds. This compound stabilizes various proteins and enzymes against temperature fluctuations without triggering an innate immune response. Additionally, Poly(styrenyl acetal trehalose) can be utilized in synthesizing protein-polymer conjugates, thereby reducing the renal clearance of active molecules.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | Poly(styrenyl acetal trehalose) (pSAT) is synthesized by linking trehalose side chains to a polystyrene backbone through acetal bonds. This compound stabilizes various proteins and enzymes against temperature fluctuations without triggering an innate immune response. Additionally, Poly(styrenyl acetal trehalose) can be utilized in synthesizing protein-polymer conjugates, thereby reducing the renal clearance of active molecules. |
| In vivo | When administered to mice, poly(styrenyl acetal trehalose) at a dose of 10 mg/kg intravenously as a single dosage does not cause liver or kidney damage and is considered safe regarding acute toxicity. Additionally, at a dosage of 1 mg/kg delivered intraperitoneally twice (on day 0 and day 14), it does not lead to increased levels of pro-inflammatory cytokines and IgG. |
| Synonyms | pSAT |
| Formula | C23H34O11 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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