gic

Trimebutine CTB salt (GIC-1001) is an opioid receptor agonist used in the study of pain.

α-Conotoxin GIC is a selective and potent antagonist of the α3β2 nicotinic acetylcholine receptor, exhibiting an inhibition constant (IC50) of 1.1 nM [1].

GIC-20, a dual inducer of apoptosis and ferroptosis, exhibits antitumor efficacy against fibrosarcoma [1].

GW280264X (Carbamic acid) is an inhibitor of ADAM17 .

Ellagic acid (Gallogen), a thickened tetracyclic natural product, is a potent CK2 inhibitor (IC50=40 nM; Ki=20 nM) with ATP-competitive properties. Ellagic acid is an antioxidant and also possesses antiproliferative activity.

Syringic acid (3,5-dimethoxy-4-hydroxy Benzoic Acid) (SYRA) is a potential antioxidant used in traditional Chinese medicine and is an emerging nutraceutical. It has potential anti-angiogenic, anti-glycating, anti-hyperglycaemic, neuroprotective, and memory-enhancing properties.

Ellagic Acid Dihydrate inhibit the CYP1A1-dependent activation of benzo[a]pyrene.

Temgicoluril (mebikar) acts on GABA Receptor.

30-Hydroxygambogic acid is a useful organic compound for research related to life sciences and the catalog number is T124009.

3,4'-Di-O-methylellagic acid is a useful organic compound for research related to life sciences and the catalog number is T124627.

3-Methyl ellagic acid is a useful organic compound for research related to life sciences and the catalog number is T124735.

Isocalolongic acid is a useful organic compound for research related to life sciences. The catalog number is T124889 and the CAS number is 40737-92-6.

3-O-Methylellagic acid 3'-O-alpha-rhamnopyranoside is a useful organic compound for research related to life sciences and the catalog number is T124973.

4,4'-Di-O-methylellagic acid [CAS 3374-77-4, catalog number T125016] is a valuable organic compound for life sciences research.

Cimicifugic acid F is a useful organic compound for research related to life sciences and the catalog number is T125319.

Gambogic acid A is a useful organic compound for research related to life sciences and the catalog number is T125707.

9R-10alpha-Hydroxyepigambogic acid is a useful organic compound for research related to life sciences and the catalog number is T126415.

Longicaulenone is a useful organic compound for research related to life sciences and the catalog number is T130680.

CDK9 autophagic degrader 1 (Compound 28) is an ATTEC degrader used to target and degrade CDK9, also impacting the levels of its associated Cyclin T1. At a concentration of 100 nM, it exhibits over 80% inhibition of CDK9.

PCSK9 autophagic degrader 2 (W6) is an autophagosome-targeting agent for PCSK9, with a DC50 value of 20.6 nM. It exhibits effects comparable to anti-atherosclerotic treatments and has a binding constant (KD) with LC3B of 2.5 μM.

PDEδ autophagic degrader 1 (compound 12c) is an autophagosome-tethering compound (ATTEC) and a potent autophagic degrader of PDEδ. This compound effectively reduces PDEδ protein levels through lysosome-mediated autophagy without affecting PDEδ mRNA expression. Additionally, PDEδ autophagic degrader 1 inhibits the growth of KRAS mutant pancreatic cancer cells.

Longicautadine is an alkaloid isolated from stembark of Strychnos chrysophylla.

Longicin is a cytotoxic agent isolated from Asimina longifolia.

Longicoricin is a monotetrahydrofuran Annonaceous acetogenin from Asimina longifolia.