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Levobunolol hydrochloride

Name: Levobunolol hydrochloride
Brand: TargetMol
SKU: T15742
Rating: 4.5 (1 reviews)

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Catalog No. T15742Cas No. 27912-14-7

Alias l-Bunolol hydrochloride

Levobunolol hydrochloride is a non-selective blocker of β-adrenergic receptor and can be used in studies about managing glaucoma and superior oblique myokymia.

Levobunolol hydrochloride

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Purity: 98.49%

Catalog No. T15742Alias l-Bunolol hydrochlorideCas No. 27912-14-7

Levobunolol hydrochloride is a non-selective blocker of β-adrenergic receptor and can be used in studies about managing glaucoma and superior oblique myokymia.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$59	4-6 weeks	4-6 weeks
25 mg	$88	4-6 weeks	4-6 weeks
1 mL x 10 mM (in DMSO)	$64	4-6 weeks	4-6 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.49%

Appearance:Solid

Color:White

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Levobunolol hydrochloride is a non-selective blocker of β-adrenergic receptor and can be used in studies about managing glaucoma and superior oblique myokymia.
Synonyms	l-Bunolol hydrochloride

Chemical Properties

Molecular Weight	327.85
Formula	C₁₇H₂₆ClNO₃
Cas No.	27912-14-7
Smiles	Cl.CC(C)(C)NC[C@H](O)COc1cccc2C(=O)CCCc12
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 50 mg/mL (152.51 mM), Sonication is recommended.

DMSO: 56.3 mg/mL (171.72 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2.5 mg/mL (7.63 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0502 mL	15.2509 mL	30.5018 mL	152.5088 mL
5 mM	0.6100 mL	3.0502 mL	6.1004 mL	30.5018 mL
10 mM	0.3050 mL	1.5251 mL	3.0502 mL	15.2509 mL
20 mM	0.1525 mL	0.7625 mL	1.5251 mL	7.6254 mL
50 mM	0.0610 mL	0.3050 mL	0.6100 mL	3.0502 mL
100 mM	0.0305 mL	0.1525 mL	0.3050 mL	1.5251 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc