azo

Benzoic acid, m-((p-methylaminophenyl)azo)- is a bioactive chemical.

Benzyl alcohol, m-((p-aminophenyl)azo)- is a bioactive chemical.

Azo-Resveratrol is an analog of Resveratrol used as a potent tyrosinase inhibitor.

2-Methyl-5-(p-tolyldiazenyl)aniline is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Carmoisine (Azo Rubine) is a food dye Azorubine and is used for the purposes where food is heat-treated after fermentation.

2-Methyl-5-(p-tolyldiazenyl)aniline-d6 (o-Toluene-azo-o-toluidine-d6) is the deuterium-labeled form of 2-Methyl-5-(p-tolyldiazenyl)aniline. This compound serves as a biochemical reagent and can be utilized as a biomaterial or organic compound in life sciences research.

7,7-Azo-3-α,12-α-dihydroxycholanic acid is a light-unstable (photo-crosslinking) derivative of cholic acid with reduced affinity for high-density lipoprotein (HDL).

Azo-PROTAC-4C-cis is a BCR-ABL PROTAC degrader, exhibiting a lower efficiency in degrading BCR-ABL compared to its trans isomer, Azo-PROTAC-4C-trans. The cis isomer forms as a result of a configurational change of Azo-PROTAC-4C-trans when exposed to ultraviolet light (UV). Under visible light, Azo-PROTAC-4C-cis can be converted back to the highly active Azo-PROTAC-4C-trans, initiating protein degradation. This compound is useful for studying myeloid leukemia.

Azo-PROTAC-4C-trans is a BCR-ABL PROTAC degrader that efficiently targets BCR-ABL fusion proteins and ABL proteins. It exhibits strong, selective antiproliferative activity against K562 cells. The activity of Azo-PROTAC-4C-trans can be precisely and reversibly controlled through UV (for inactivation)/visible light (for activation) irradiation. This compound is applicable for myeloid leukemia research.

18:0-azo PC is an analog of phosphatidylcholine (PC). Upon exposure to light, it can be photoactivated or deactivated, causing the azobenzene segment within the molecule to undergo cis/trans isomerization, thereby initiating or terminating cell signaling pathways.

Azo Coenzyme A ammonium is a derivative of coenzyme A.

m-((3-Amino-4-hydroxyphenyl)azo)benzenesulphonic acid is a bioactive chemical.

m-((4-((4-(Bis(2-hydroxyethyl)amino)phenyl)azo)-1-naphthyl)azo)benzenesulphonic acid is a bioactive chemical.

m-((4-((4-Hydroxy-m-tolyl)azo)-3-methoxyphenyl)azo)benzenesulphonic acid is a bioactive chemical.

Pioglitazone (U 72107) is a PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively, and has selective and oral activity. Pioglitazone can be used in diabetes research.

Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidinedione insulin sensitizer.

Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.

Oxazolone is a haptenating agent that can induce models of acute or chronic colitis and atopic dermatitis. It activates Th1/Th2 responses, leading to weight loss and diarrhea, and the resulting inflammation can be alleviated by anti-IL-4 antibodies, anti-TNF-α antibodies, or IL-13R2α-Fc fusion proteins. It is also suitable for studying gene expression related to inflammatory bowel disease in zebrafish.

Imidazole ketone erastin (IKE) is an ferroptosis inducer with inhibitory effects on system Xc-cystine/glutamate transporter proteins. Imidazole ketone erastin has antitumor activity and induces glutathione depletion and lipid peroxidation.

Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).

Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist that triggers STING signaling pathway activation and type I interferon activation. Dazostinag disodium (TAK-676) is also a highly effective immune system modulator with complete resolution and lasting memory of T cell immunity and the ability to promote lasting interferon-dependent anti-tumor immune responses.

Azoxymethane (AOM) is a colon-specific carcinogen that induces DNA damage and forms DNA adducts, and is commonly used to establish mouse models of colorectal cancer.

6-Diazo-5-oxo-L-nor-Leucine (DON) is a glutamine antagonist, an irreversible glutaminolysis inhibitor (Ki=6 μM) with antitumor (particularly pancreatic cancer), antibacterial, and antiviral activities.

Dextrorotation nimorazole phosphate ester TFA is an anti-anaerobic and anti-parasitic agent.