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Hydroxy Itraconazole D8

Name: Hydroxy Itraconazole D8
Brand: TargetMol
SKU: T11585
Price: 392 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T11585 Copy Product Info

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Hydroxy Itraconazole D8 is a deuterated compound of itraconazole, commonly used for isotope labeling, primarily in pharmacokinetic studies, isotope-labeled analysis, and metabolic studies. Hydroxy Itraconazole is an active metabolite of itraconazole (ITZ).

Hydroxy Itraconazole D8

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Catalog No. T11585

Pack Size	Price	USA Stock	Global Stock
1 mg	$392	-	In Stock
5 mg	$1,200	7-10 days	7-10 days
10 mg	$1,960	7-10 days	7-10 days
25 mg	$3,700	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	729.68
Formula	C₃₅H₃₀D₈Cl₂N₈O₅
Smiles	O=C1N(C(C(C([2H])([2H])[2H])([2H])O)([2H])C([2H])([2H])[2H])N=CN1C2=CC=C(N3CCN(CC3)C4=CC=C(C=C4)OCC5OC(C6=CC=C(C=C6Cl)Cl)(CN7N=CN=C7)OC5)C=C2
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 66.66 mg/mL (91.36 mM), Sonication is recommended.

H2O: < 1?mg/mL?(insoluble), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3705 mL	6.8523 mL	13.7046 mL	68.5232 mL
5 mM	0.2741 mL	1.3705 mL	2.7409 mL	13.7046 mL
10 mM	0.1370 mL	0.6852 mL	1.3705 mL	6.8523 mL
20 mM	0.0685 mL	0.3426 mL	0.6852 mL	3.4262 mL
50 mM	0.0274 mL	0.1370 mL	0.2741 mL	1.3705 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Citations

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc