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Results for "

ros

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    1913
    TargetMol | Inhibitors_Agonists
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    8
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    57
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    TargetMol | Natural_Products
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    TargetMol | Inhibitors_Agonists
ROS inducer 1
T775742921602-31-3
ROS inducer 1 is a small molecule compound with bactericidal activity that inhibits the production of ROS in Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo) and Pseudomonas syringae pv. actinidiae (Psa). ROS inducer 1 induces ROS production in Xanthomonas cells and can be used to study bacterial infections in crops.
  • $195
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Ferrostatin-1
Ferrostatin-1 (Fer-1), Ferrostatin 1
T6500347174-05-4
Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death. Ferrostatin-1 potently inhibits Erastin-induced iron death in HT-1080 cells with an EC50 of 60 nM. Ferrostatin-1 also exhibits antioxidant and antifungal activities.
  • $59
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Acetylcysteine
N-Acetyl-L-cysteine, N-Acetylcysteine, N-Acetyl Cysteine, NAC, LNAC
T0875616-91-1
Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis, can be used to reduce mucus thickness, and has anti-influenza viral activity.
  • $33
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sfi003
T720682361332-90-1In house
SFI003 is a novel SRSF3 inhibitor that exerts anticancer activity against colorectal cancer by modulating the SRSF3 DHCR24 ROS axis and driving apoptosis in CRC cells through the SRSF3 DHCR24 reactive oxygen species (ROS) axis.
  • $84
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Tenivastatin
Simvastatin hydroxy acid, Simvastatin acid, L-654969, L654969, L 654969
T24865121009-77-6In house
Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor that inhibits the production of reactive oxygen species (ROS) and can be used in the study of primary hyperlipidemia.
  • $350 TargetMol
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BRD56491
BRD-56491, BRD 56491
T3058214756-26-4In house
BRD56491 is a small molecule ROS enhancer and a bioprobe for the detection of cancer.
  • $293 TargetMol
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Sonlicromanol hydrochloride
KH 176 hydrochloride
T380132162149-24-6In house
Sonlicromanol hydrochloride (KH176 hydrochloride) is a ROS-redox modulator that crosses the blood-brain barrier, has potential anticancer activity, improves m.3243A>G heterogeneity in iPSC-derived neurons associated with It has potential anticancer activity, ameliorates neuronal network dysfunction and transcriptomic changes associated with m.3243A>G heterogeneity in iPSC-derived neurons, and can be used for the treatment of mitochondrial diseases.
  • $158 TargetMol
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S1R agonist 2
T72059150085-21-5In house
S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
  • $34
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BChE/HDAC6-IN-2
T776582925457-33-4In house
BChE HDAC6-IN-2 is a selective and potent dual inhibitor of BChE and HDAC6 with neuroprotective and reactive oxygen species (ROS) scavenging activity. BChE HDAC6-IN-2 is a metal ion co-agonist that inhibits tau phosphorylation and can be used in the study of immune and neurological diseases.
  • $195
4-6 weeks
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Gallic acid
Gallate, 3,4,5-Trihydroxybenzoic acid
T0877149-91-7
Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.
  • $38
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Crizotinib
PF-02341066
T1661877399-52-5
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinase inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptors.
  • $46
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Compound T2841(SC)
Plumbagone, Plumbagine, Plumbaein, 2-Methyljuglone
T2841481-42-5
Plumbagin (Plumbaein) is a yellow dye, formally derived from naphthoquinone. It is named after the plant genus Plumbago, from which it was originally isolated. It is also commonly found in the carnivorous plant genera Drosera and Nepenthes. It is also a component of the black walnut drupe.
  • $34
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Lycopene
ψ,ψ-Carotene
T2864502-65-8
Lycopene (ψ,ψ-Carotene) is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. As a class, carotenoids are pigment compounds found in photosynthetic organisms (plants, algae, and some types of fungus), and are chemically characterized by a large polyene chain containing 35-40 carbon atoms; some carotenoid polyene chains are terminated by two 6-carbon rings. In animals, carotenoids such as lycopene may possess antioxidant properties which may retard aging and many degenerative diseases. As an essential nutrient, lycopene is required in the animal diet.
  • $50
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Tempone
4-Oxo-tempo
T365062896-70-0
Tempone is an aminooxyalkane that acts as a free radical scavenger and reacts with reactive oxygen species (ROS). Intravenous Tempone reduces mean arterial pressure in spontaneously hypertensive rats.
  • $35
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Entrectinib
RXDX-101, NMS-E628
T36781108743-60-7
Entrectinib (RXDX-101) is a Trk, ROS1, and ALK inhibitor that inhibits TrkA, TrkB, TrkC, ROS1, and ALK (IC50=1 3 5 12 7 nM) with oral activity and blood-brain-barrier penetration. Entrectinib exhibits both antitumor and CNS activity.
  • $35
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N-acetylcysteine amide
T551838520-57-9
N-Acetylcysteine amide is a thiol antioxidant and a neuroprotective agent with cell permeability and blood-brain barrier permeability. N-Acetylcysteine amide reduces ROS production.
  • $39
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(E/Z)-Squalene
(E Z)-Super Squalene, (E Z)-AddaVax
T756367683-64-9
(E Z)-Squalene ((E Z)-AddaVax) regulates intracellular reactive oxidant species (ROS) production, induces apoptosis and necrosis in a concentration- and time-dependent manner, accumulates in the liver, and lowers hepatic cholesterol and triglycerides.
  • $50
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(±)-Catechin
T82557295-85-4
(±)-Catechin ((±)-Catechin hydrate) hydrate is a natural product,has antioxidant activity and is effective in reducing oxidative stress.
  • $30
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(-)-Perillaldehyde
T911218031-40-8
(-)-Perillaldehyde shows antibacterial activity.
  • $30
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Ethyl cinnamate
TN1624103-36-6
Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl cinnamate can inhibit the tonic contractions induced by high K+ and phenylephrine (PE) in a concentration-dependent manner, with respective IC50 values of 0.30 mM and 0.38 mM.
  • $29
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Merestinib
LY2801653
T34551206799-15-6
Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. Merestinib electively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing the constitutively activated c-Met protein.
  • $45
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Cannabigerol
TN146525654-31-3
Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressure, which may be of benefit in the treatment of glaucoma.
  • $148
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chbo4
T7757898991-32-3
CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the Ki value was 0.010 ± 0.005 μM.CHBO4 reduces cellular damage by scavenging intracellular reactive oxygen species (ROS), and can be used to study Parkinson's disease (PD).
  • $31
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T-2 Toxin
T-2 Mycotoxin
T1305321259-20-1
T-2 Toxin (T-2 Mycotoxin) is a fungal secondary metabolite produced by various Fusarium species in feed and grains, which is highly toxic to reproduction and induces a variety of cardiovascular toxicities.T-2 Toxin is an inhibitor of peptidyl transferase (60s ribosomal subunit) binding and protein synthesis. T-2 Toxin is an inhibitor of peptidyl transferase (60s ribosomal subunit) binding and protein synthesis, induces TM4 cell dysfunction via ROS-induced apoptosis, inhibits DNA and RNA synthesis, and increases hepatic lipid peroxidation levels.
  • $253
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