cd3

Anti-Mouse CD3 Antibody (17A2) is a murine IgG2b class antibody targeting CD3, which can be used to study TCR signaling, T cell activation and antigen recognition.

Cibisatamab is a T-cell bispecific antibody that acts as a T-cell splicer.Cibisatamab targets carcinoembryonic antigen (CEA) on cancer cells and CD3 on T-cells, and triggers T-cell killing when the CEA on the surface of the cancer cells ranges from intermediate to high levels.Cibisatamab may be used to study solid cancers such as colorectal cancer.

Mosunetuzumab (BCT-4465A) is a humanized antibody based on immunoglobulin G1 that targets CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used to study relapsed or refractory (R R) B-cell non-Hodgkin lymphoma (B-NHL) and refractory follicular lymphoma.

Teplizumab (MGA-031) is a humanized monoclonal antibody targeting CD3 that slows the loss of beta cell function and is used to treat type 1 diabetes.

Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T-cell binding domain (CD3) with antitumor activity for the study of gastric neurosecretory tumors.

Epcoritamab (GEN3013) is a novel subcutaneous CD3xCD20 bispecific T-cell binding antibody that activates T-cells and directs them to kill malignant CD20(+) B-cells for the study of relapsed or refractory large B-cell lymphoma.

Anti-Mouse CD32 CD16 Antibody is a rat-derived IgG2b inhibitor targeting the mouse CD32 CD16 antigens.

Anti-CD34 Antibody is a CHO-expressed humanized monoclonal antibody targeting CD34, which can be used for the study of neurological and cardiovascular diseases.

Epcoritamab-CD3E Specific Antibody is an inhibitory antibody that can be used in life science related research.

The Anti-NKG2D CD314 Antibody (1D11) is a chimeric mouse IgG1, κ targeting NKG2D CD314 (human origin). Its isotype control is the MouseIgG1kappa, Isotype Control.

The Anti-CD32 FcγRIIA Antibody (IV.3) is a chimeric mouse IgG2b antibody designed to target human CD32 FcγRIIA. The recommended isotype control for this antibody is Mouse IgG2b kappa, Isotype Control.

Anti-Mouse CD3ε Antibody (145-2C11) consists of an Armenian hamster IgG1 subclass, specifically targeting CD3ε in mice. The recommended isotype control for this antibody is Armenian Hamster IgG, Isotype Control.

Anti-CD326 EpCAM Antibody (Ber-EP4) is a mouse IgG1, κ chimeric antibody designed to target human CD326 EpCAM. The recommended isotype control for this antibody is Mouse IgG1 kappa, Isotype Control.

The Anti-Mouse TIM-1 CD365 Antibody (3D10) is a rat-derived IgG1 kappa monoclonal antibody that targets mouse TIM-1 CD365. Its isotype control is Rat IgG1 kappa, Isotype Control.

The Anti-TIM-1 KIM-1 CD365 Antibody (2.70.2) is a type of antibody targeting TIM KIM-1 CD365.

The Anti-Mouse NKG2D CD314 Antibody (HMG2D) is an antibody of mouse origin, specifically an IgG derived from American hamster, targeting NKG2D CD314. The isotype control for Anti-Mouse NKG2D CD314 Antibody (HMG2D) is Armenian hamster IgG, Isotype Control.

Anti-Mouse CD3E Antibody (1E11.D) is an IgG1 antibody inhibitor targeting the mouse CD3E molecule.

Anti-Mouse CD38 Antibody (NIMR5) is an IgG2a, κ inhibitor antibody derived from rats, designed to target and inhibit mouse CD38.

The Anti-Mouse NKG2D CD314 Antibody (CX5) is a rat-derived IgG1, κ antibody known for its inhibitory function against mouse NKG2D CD314.

Anti-Mouse CD3ε Antibody (KT3) is an IgG2a inhibitor derived from rats, specifically targeting mouse CD3ε.

Anti-Human-CD38 Antibody (Daratumumab hexabody) is an antibody. Its expression system is HEK293 cells, and the isotype control is IgG1, Kappa.

ABP-102 (CT P72) is a tetravalent IgG1-[L]-scFv bispecific t-cell adduct (BiTE) that acts as a CD3 modulator and selective HER2 modulator for the selective targeting of HER2 overexpressing tumors. ABP-102 showed cytotoxicity in HER2-overexpressing models of breast and gastric cancers, while significantly decreasing activity against HER2 low level cells, twice as effective as rununmotamab.

Odronextamab, a fully human, hinge-stabilized IgG4-based bispecific antibody, targets CD3 receptors on T cells and CD20 receptors on B cells [1].

Muromonab (OKT3) is a murine monoclonal antibody targeting CD3 receptors, blocking all cytotoxic T-cell functions. It reverses acute organ transplant rejection and is used in studies of acute graft rejection.