il-1α

IL-1 alpha IL-1A Protein, Rat, Recombinant (CHO) is expressed in CHO Cells. The accession number is P16598-1.

Expression system: HEK293 Cells
Length: 113-271, Full Length of Mature Protein
Activity: Not Tested

IL-1 beta IL-1F2 Protein, Mouse, Recombinant (CHO) is expressed in CHO Cells. The accession number is P10749.

Expression system: E. coli
Length: 113-271, Full Length of Mature Protein
Activity: Cell Activity

Expression system: HEK293 Cells
Length: 113-271, Full Length of Mature Protein
Activity: Cell Activity

Expression system: E. coli
Length: 1-269 (mutation), Full Length
Activity: ELISA

IL-1 beta IL-1F2 Protein, Human, Recombinant (CHO) is expressed in CHO Cells. The accession number is P01584.

Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 expression is induced by type1 and type2 interferons, including IFN-λ and also by interleukin-1β (IL-1β), IL-1α, and tumor necrosis factor-α (TNF-α). GBP-1 is key to the protective immunity against microbial and viral pathogens. GBP-1 was only secreted from endothelial cells. Secretion occurred without the presence of a leader peptide. Secretion procession is a nonclassical, likely ABC transporter-dependent, pathway and independent of GBP-1 GTPase activity and isoprenylation, and did not require additional interferon-λ-induced factors. Clinically most important was the detection of significantly increased GBP-1 concentrations in the cerebrospinal fluid of patients with bacterial meningitis as compared to control patients.

Expression system: HEK293 Cells
Length: 21-367, Extracellular Domain
Activity: Not Tested