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Anti-CD121B Monoclonal Antibody (4O931)

(Synonyms: IL-1RT-2, IL-1RT2, IL1RB, IL1R2c, IL-1R-2, IL1R2, CDw121b) Copy Product Info
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Synonyms: IL-1RT-2, IL-1RT2, IL1RB, IL1R2c, IL-1R-2, IL1R2, CDw121b

Catalog No. TMAT-0258 Copy Product Info
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Anti-CD121B Monoclonal Antibody (4O931) is a Mouse antibody targeting CD121B. Anti-CD121B Monoclonal Antibody (4O931) can be used in IF,FCM.

Anti-CD121B Monoclonal Antibody
(4O931)

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Product Introduction

Bioactivity
Description
Anti-CD121B Monoclonal Antibody (4O931) is a Mouse antibody targeting CD121B. Anti-CD121B Monoclonal Antibody (4O931) can be used in IF,FCM.
SynonymsIL-1RT-2, IL-1RT2, IL1RB, IL1R2c, IL-1R-2, IL1R2, CDw121b
Ig Type
IgG1
Clone
4O931
Reactivity
Human
Application
Recommended Dose
IF: 1/50-1/200; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThe protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human CD121B (AA: extra 14-343) expressed in HEK293-6e cells supernatant.
Antigen Species
Human
Gene Name
IL1R2
Gene ID
Protein Name
Interleukin-1 receptor type 2
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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