Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Apoptosis
    (39)
  • Autophagy
    (29)
  • COX
    (385)
  • IL Receptor
    (24)
  • Lipoxygenase
    (29)
  • NF-κB
    (61)
  • NOS
    (35)
  • Prostaglandin Receptor
    (33)
  • TNF
    (35)
  • Others
    (178)
Filter
Search Result
Results for "

cox

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    655
    TargetMol | Activity
  • Compound Libraries
    1
    TargetMol | inventory
  • Peptide Products
    2
    TargetMol | natural
  • Inhibitory Antibodies
    4
    TargetMol | composition
  • Dye Reagents
    3
    TargetMol | Activity
  • Natural Products
    220
    TargetMol | inventory
  • Recombinant Protein
    13
    TargetMol | natural
  • Isotope Products
    29
    TargetMol | composition
Lumiracoxib
T6574220991-20-8
Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.
  • $31
In Stock
Size
QTY
TargetMol | Inhibitor Sale
TargetMol | Citations Cited
FK 3311
T7207116686-15-8
FK 3311 (COX-2 Inhibitor V) is an orally available, cell-permeable sulfonanilide that functions as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (NSAID).
  • $38
In Stock
Size
QTY
TargetMol | Inhibitor Sale
COX-2-IN-34
T776182788578-71-0
COX-2-IN-34 is a selective, orally potent COX-2 inhibitor that shows anti-inflammatory activity without gastric ulcer toxicity during experiments in mice.
  • $195
In Stock
Size
QTY
COX-2-IN-2
T10032134729-13-8In house
COX-2-IN-2, a selective inducible COX2 inhibitor, exhibits potent inhibition with an IC50 of 0.24 μM. Meanwhile, COX-2-IN-1 functions as an anti-inflammatory agent, demonstrating both anti-inflammatory and analgesic activities.
  • $497
In Stock
Size
QTY
TargetMol | Inhibitor Sale
COX-2-IN-1
T10033787623-48-7In house
COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).
  • $117
In Stock
Size
QTY
TargetMol | Inhibitor Sale
COX-2-IN-6
T620612756347-91-6In house
COX-2-IN-6 is a potent, selective, and orally available cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 0.84 μM and a Ki of 69 nM.COX-2-IN-6 inhibits COX-2-driven PGE2 synthesis with an IC50 of 0.60 μM.COX-2-IN-6 is used to prevent colorectal cancer. COX-2-IN-6 can be used to prevent colorectal cancer.
  • $67
In Stock
Size
QTY
COX-2-IN-31
T78706
COX-2-IN-31 (compound 7b) is an orally active dual inhibitor targeting COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 μM), and also inhibits transmembrane hCA IX (Ki=48.9 nM) and hCA XII (Ki=5.8 nM), demonstrating anti-inflammatory and analgesic activity [1].
  • Inquiry Price
Size
QTY
COX-1/2-IN-4
T79592
COX-1 2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2, and demonstrates moderate anticancer activity with IC50 values of 30.79 μM against COLO205 cancer cell lines and 74.15 μM against B16F1 cancer cell lines [1].
  • Inquiry Price
Size
QTY
COX-2-IN-35
T79760
COX-2-IN-35 (compound 7) is a selective COX-2 inhibitor with anti-inflammatory activity, exhibiting an inhibitory concentration (IC 50) of 4.37 nM [1].
  • Inquiry Price
Size
QTY
COX-2-IN-30
T787051160498-08-7
COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 = 10.4 μM), as well as 5-lipoxygenase (5-LOX; IC50 = 2.4 μM). Additionally, it inhibits the transmembrane isoforms of human carbonic anhydrase IX and XII with nanomolar class Ki values. Demonstrating analgesic and anti-inflammatory properties, COX-2-IN-30 is devoid of acute gastric effects, avoiding ulcerogenic activity [1].
  • Inquiry Price
8-10 weeks
Size
QTY
COX-2-IN-33
T78754
COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 of 45.5 nM, demonstrating potential as an anti-inflammatory agent by effectively suppressing pro-inflammatory cytokine production in vivo while maintaining gastric safety [1].
  • Inquiry Price
Size
QTY
COX-1/2-IN-5
T79594
COX-1 2-IN-5 (compound 2a) is a dual inhibitor of COX1 2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and exhibits anticancer activity against liver cancer HepG2 cells with an IC50 of 60.75 μM [1].
  • Inquiry Price
Size
QTY
COX/5-LO-IN-1
T13263154355-75-6
COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.
  • $1,520
6-8 weeks
Size
QTY
Valdecoxib
T0219181695-72-7
Valdecoxib (SC 65872) is a prescription drug used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is classified as a nonsteroidal anti-inflammatory drug, or NSAID, and should not be taken by anyone allergic to these types of medications.
  • $59
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Rofecoxib
T1185162011-90-7
Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with anti-inflammatory, antipyretic and analgesic properties and potential antineoplastic properties. COX-related metabolic pathways may represent key regulators of cell proliferation and neo-angiogenesis. Some epithelial tumor cell types overexpress pro-angiogenic COX-2.
  • $38
In Stock
Size
QTY
Etoricoxib
T1574202409-33-4
Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.
  • $34
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Parecoxib
T1780198470-84-7
Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.
  • $30
In Stock
Size
QTY
Deracoxib
T0484169590-41-4
Deracoxib (SC 46) is a non-steroidal, non-narcotic anti-inflammatory drug. It is also a selective cyclooxygenase-2 inhibitor, and IC50 Value: 70 to 150 μM(inhibition of 3 osteosarcoma cell lines).
  • $34
In Stock
Size
QTY
TargetMol | Inhibitor Sale
TargetMol | Citations Cited
Celecoxib
T0466169590-42-5
Celecoxib (SC 58635) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of celecoxib is as a Cyclooxygenase Inhibitor.
  • $30
In Stock
Size
QTY
TargetMol | Citations Cited
S-2474
T16817158089-95-3In house
S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities and inhibits Abeta (25 - 35) and Abeta (1 - 40) induced cell death.
  • $293 TargetMol
In Stock
Size
QTY
Eltenac
T2725472895-88-6In house
Eltenac (B78820) is a non-steroidal anti-inflammatory, COX inhibitor with analgesic activity.Eltenac inhibits COX-1 and COX-2 and is used in the study of Acute Respiratory Distress Syndrome (ARDS).
  • $383 TargetMol
In Stock
Size
QTY
Tenidap
T17036120210-48-2In house
Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.
  • $30 TargetMol
In Stock
Size
QTY
BN-82451 2HCl
T26878663172-95-0In house
BN-82451 2HCl is a dual inhibitor of COX-1 and COX-2 and can be used to study Huntington's chorea and Parkinson's disease.
  • $293 TargetMol
In Stock
Size
QTY
Floctafenine
T2733523779-99-9In house
Floctafenine (R-4318) is an orally available nonsteroidal anti-inflammatory compound that is a COX-I and COX-2 inhibitor and interferes with the antiplatelet effects of aspirin.Floctafenine has analgesic activity and is used in the study of pain.
  • $293 TargetMol
In Stock
Size
QTY
Ampyrone
T005083-07-8
Ampyrone (4-Aminoantipyrine) is a reagent for glucose determination in the presence of peroxidase and phenol.
  • $35
In Stock
Size
QTY
TargetMol | Inhibitor Sale
2,5-Di-tert-butylhydroquinone
T754088-58-4
2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.
  • $29
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Etodolac
T100241340-25-4
Etodolac (AY-24236) inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. Etodolac is a pyranocarboxylic acid and non-steroidal anti-inflammatory drug (NSAID) with antipyretic and analgesic activities. It also inhibits platelet aggregation by blocking platelet cyclooxygenase and the subsequent formation of thromboxane A2.
  • $34
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Sodium salicylate
T033554-21-7
Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.
  • $45
In Stock
Size
QTY
Ketoprofen
T083922071-15-4
Ketoprofen (RP-19583) is a propionic acid derivative and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. It inhibits cyclo-oxygenase I and II, decreasing the formation of prostaglandin and thromboxane precursors. This reduction in prostaglandin synthesis, mediated by prostaglandin synthase, is responsible for its therapeutic effects. Additionally, Ketoprofen decreases thromboxane A2 formation via thromboxane synthase, inhibiting platelet aggregation.
  • $45
In Stock
Size
QTY
Triflusal
T0705322-79-2
Triflusal (UR1501) is a 2-acetoxy-4-trifluoromethylbenzoic acid and it is an aspirin chemically-related molecule but not a derivative.
  • $39
In Stock
Size
QTY
Flunixin meglumine
T120942461-84-7
Flunixin meglumine (Banamine) is an effective inhibitor of the enzyme cyclooxygenase with anti-inflammatory and antipyretic activity.
  • $42
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Flurbiprofen
T02915104-49-4
Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.
  • $50
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Diclofenac Potassium
T647015307-81-0
Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
  • $33
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Acetaminophen
T0065103-90-2
Acetaminophen (APAP) is a COX inhibitor that inhibits COX-1 and COX-2 (IC50=113.7 25.8 μM). Acetaminophen has antipyretic and analgesic activity as well as weak anti-inflammatory activity.
  • $41
In Stock
Size
QTY
TargetMol | Citations Cited
Catechin
T0822154-23-4
Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant.
  • $30
In Stock
Size
QTY
TargetMol | Citations Cited
Xanthohumol
T33426754-58-1
Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated chalcones. It inhibits COX-1 and COX-2 activity and shows chemopreventive effects.
  • $61
In Stock
Size
QTY
Salicylic acid
T064969-72-7
Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.
  • $33
In Stock
Size
QTY
3-Carene
T1010913466-78-9
3-Carene(Delta-3-Carene) is a bicyclic monoterpene extracted from western larch and Douglas-fir that acts as a phytofungicide.3-Carene inhibits inflammatory infiltrates and COX-2 overexpression induced by nociceptive stimuli.3-Carene has anti-injury properties and promotes the activity and expression of alkaline phosphatase, an early marker of osteoblast differentiation.
  • $30
In Stock
Size
QTY
Flufenamic acid
T0858530-78-9
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically.
  • $33
In Stock
Size
QTY
Resveratrol
T1558501-36-0
Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targets including COX, SIRT, LOC, etc. Resveratrol induces autophagy and apoptosis.
  • $36
In Stock
Size
QTY
TargetMol | Citations Cited
Ketorolac
T2141274103-06-3
Ketorolac (Acuvail) is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives. It acts by inhibiting the bodily synthesis of prostaglandins.
  • $42
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Propyphenazone
T5010479-92-5
Propyphenazone (4-Isopropylantipyrine), a pyrazolone derivative, exhibits anti-inflammatory, analgesic, and antipyretic properties and acts as a precursor for prodrugs and selective cyclooxygenase-2 inhibitors.
  • $40
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Bromfenac Sodium
T642491714-93-1
Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.
  • $47
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Firocoxib
T7596189954-96-9
Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cyclooxygenase-2 (COX-2) with an IC50 of 0.13 μM, used for its anti-inflammatory properties in dogs and horses.
  • $41
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Veratric acid
T374493-07-2
Veratric acid (3,4-Dimethoxybenzoic acid) is a benzoic acid derivative from plants and fruits, possessing antioxidant, anti-inflammatory, and blood pressure-lowering properties.
  • $31
In Stock
Size
QTY
Mefenamic acid
T089061-68-7
Mefenamic acid (CN-35355) is a non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
  • $31
In Stock
Size
QTY
TargetMol | Inhibitor Sale
TargetMol | Citations Cited
Oxaprozin
T070821256-18-8
Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor. The chemical classification of oxaprozin is Nonsteroidal Anti-inflammatory Compounds.
  • $45
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Pranoprofen
T015952549-17-4
Pranoprofen (Pyranoprofen) (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.
  • $35
In Stock
Size
QTY
TargetMol | Inhibitor Sale