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Synonyms: PDCD8, MGC111425, COXPD6, AIFM1, AIF
Anti-AIF Monoclonal Antibody
(8L267)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
| Description | Anti-AIF Monoclonal Antibody (8L267) is a Mouse antibody targeting AIF. Anti-AIF Monoclonal Antibody (8L267) can be used in WB,IHC,IF,FCM. |
| Synonyms | PDCD8, MGC111425, COXPD6, AIFM1, AIF |
| Ig Type | IgG2b |
| Clone | 8L267 |
| Reactivity | Human,Mouse,Rat,,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10 |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human AIF expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | AIFM1 |
| Gene ID | |
| Protein Name | Apoptosis-inducing factor 1, mitochondrial |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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