3-azido-3-deoxy-4-hydroxy-methyl-1,2-o-isopropylidene-α-d-ribofuranose

3-Azido-3-deoxy-4-hydroxy-methyl-1,2-O-isopropylidene-α-D-ribofuranose is a biochemical reagent utilized in glycobiology research. This field examines the structure, synthesis, biology, and evolution of sugars. It encompasses carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the roles of glycans in biological systems. Glycobiology is closely linked with fundamental research, biomedicine, and biotechnology.

Pseudopelletierine is the main alkaloid derived from the root-bark of Punica granatum, along with at least three other alkaloids: isopelletierine, methylpelleteirine (C9H17ON) and pelletierine, which yield 1.8, 0.01, 0.20 and 0.52 grams per kilogram of ra

Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. bovisbiofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron.2It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively).3Nocardamine also induces morphological changes in BM-N4 insect cells.4 1.Lopez, J.A.V., Nogawa, T., Futamura, Y., et al.Nocardamin glucuronide, a new member of the ferrioxamine siderophores isolated from the ascamycin-producing strain Streptomyces sp. 80H647J. Antibiot. (Tokyo)72(12)991-995(2019) 2.Ishida, S., Arai, M., Niikawa, H., et al.Inhibitory effect of cyclic trihydroxamate siderophore, desferrioxamine E, on the biofilm formation of Mycobacterium speciesBiol. Pharm. Bull.34(6)917-920(2011) 3.Kalinovskaya, N.I., Romaneko, L.A., Irisawa, T., et al.Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activityMicrobiol. Res.166(8)654-661(2011) 4.Matsubara, K., Sakuda, S., Tanaka, M., et al.Morphological changes in insect BM-N4 cells induced by nocardamineBiosci. Biotechnol. Biochem.62(10)2049-2051(1998)

Acetyl-coenzyme A (Acetyl-CoA) lithium, a membrane-impermeant central metabolic intermediate, is integral to the TCA cycle and oxidative phosphorylation, regulates cellular mechanisms by serving as the sole donor of acetyl groups for post-translational acetylation of proteins, and is a critical precursor in lipid synthesis [1] [2] [3] [4].

18:0-20:4 PI(3,4,5)P3 is a reagent used in biochemical reactions.